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Protein

Glutamate racemase

Gene

murI

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathway:ipeptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei77 – 771Proton donor/acceptorUniRule annotation
Active sitei185 – 1851Proton donor/acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciVVUL216895:GIYM-1065-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:VV1_1175
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 263263Glutamate racemasePRO_0000095532Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi216895.VV1_1175.

Structurei

3D structure databases

ProteinModelPortaliQ8DD39.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni13 – 142Substrate bindingUniRule annotation
Regioni45 – 462Substrate bindingUniRule annotation
Regioni78 – 792Substrate bindingUniRule annotation
Regioni186 – 1872Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0796.
HOGENOMiHOG000262397.
KOiK01776.
OMAiPKESIYY.
OrthoDBiEOG6B6296.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8DD39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESSNQPNVL IFDSGVGGLS VFQEINKRLP EVNYYYLFDN QAYPYGELSQ
60 70 80 90 100
ETLLARVEAL VVKMTQQFAI DLVVIACNTA STIVLPTLRA KLPIPVVGVV
110 120 130 140 150
PAIKPASLLA NRAVGLIATP ATVTRQYTHD LIRDFAHEKE VELLGSTRLV
160 170 180 190 200
DIAEEKLRGR QVDQQELAMI LKPMKHKVDV AVLGCTHFPL LKEEIQQVLG
210 220 230 240 250
DEIILVDSGE AIARRVQSLL HQLSPQSTKT PWRIFSTAQP WDEAALNGSL
260
KTMGFNAIEL YPL
Length:263
Mass (Da):29,156
Last modified:March 1, 2003 - v1
Checksum:iE1D81F486EB764B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA. Translation: AAO09646.1.
RefSeqiWP_011079185.1. NC_004459.3.

Genome annotation databases

EnsemblBacteriaiAAO09646; AAO09646; VV1_1175.
KEGGivvu:VV1_1175.
PATRICi20159157. VBIVibVul94426_1117.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA. Translation: AAO09646.1.
RefSeqiWP_011079185.1. NC_004459.3.

3D structure databases

ProteinModelPortaliQ8DD39.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216895.VV1_1175.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO09646; AAO09646; VV1_1175.
KEGGivvu:VV1_1175.
PATRICi20159157. VBIVibVul94426_1117.

Phylogenomic databases

eggNOGiCOG0796.
HOGENOMiHOG000262397.
KOiK01776.
OMAiPKESIYY.
OrthoDBiEOG6B6296.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciVVUL216895:GIYM-1065-MONOMER.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
TIGRFAMsiTIGR00067. glut_race. 1 hit.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Vibrio vulnificus CMCP6."
    Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CMCP6.

Entry informationi

Entry nameiMURI_VIBVU
AccessioniPrimary (citable) accession number: Q8DD39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2003
Last modified: July 22, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.