Reviewed, UniProtKB/Swiss-Prot Q8DCX0 (SYK3_VIBVU)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	VV1_1270

Organism

Vibrio vulnificus [Complete proteome] [HAMAP]

Taxonomic identifier

672 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 323	323	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_0000152732

Sequences

	Sequence		Length	Mass (Da)
	Q8DCX0-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: ABD9CC984E9F7E5C	FASTA	323	36,147
	10 20 30 40 50 60 MQADWKPTAS IEQLRQRAVL IANIRQFFAQ RGVLEVDTPA MSHATVTDIH LHTFQTEFVG 70 80 90 100 110 120 PGYAQGRHLH LMTSPEFHMK RLLAAGSGCI YQMAKAFRNE ENGRHHNPEF TMLEWYRVGF 130 140 150 160 170 180 DHHQLMDEMD DLLQLILKCG TAERMTYQQA FLTVLGVCPL EGSMAELKSV AARLGLSDIA 190 200 210 220 230 240 EPEEDRDTLL QLLFSIGVEA KIGQQVPAFV YDFPASQAAL AKINPNDPRV ADRFEVYFKG 250 260 270 280 290 300 IELANGFHEL DNPQEQLTRF EQDNAKRIDM GLTPQPIDYH LIAALESGLP ACAGVALGVD 310 320 RLIMLSLGCT HIDEITAFPF PIA

References

[1]	"Complete genome sequence of Vibrio vulnificus CMCP6." Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E. Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CMCP6.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016795 Genomic DNA. Translation: AAO09726.1.
RefSeq	NP_760199.1.
3D structure databases
HSSP	HSSP built from PDB template 1E1O based on UniProtKB P14825.
ModBase	Search...
Genome annotation databases
GeneID	1178189.
GenomeReviews	Gene locus VV1_1270 in contig AE016795_GR.
KEGG	vvu:VV1_1270.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8DCX0.
OMA	VFRNEEA.
Enzyme and pathway databases
BioCyc	VVUL216895:VV1_1270-MON.
BRENDA	6.1.1.6. 277169.
Family and domain databases
HAMAP	MF_00174. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_VIBVU

Accession

Primary (citable) accession number: Q8DCX0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2003
Last sequence update:	March 1, 2003
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)