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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei81NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciVVUL216895:G1GJ4-1520-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:VV1_1584
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001525281 – 347tRNA pseudouridine synthase DAdd BLAST347

Structurei

3D structure databases

ProteinModelPortaliQ8DC58
SMRiQ8DC58
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 304TRUDUniRule annotationAdd BLAST147

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiGNRFFMR
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

Q8DC58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDTLASLAY LAGKPTAQAK IKAKPEHFQV REDLGFEFTG SGEHLMVRIR
60 70 80 90 100
KTGENTSFVA NELAKACGVK SKDVSWAGLK DRHAVTEQWL SVHLPKAETP
110 120 130 140 150
DFSAFLAQYP SIEILTTARH NKKLRPGDLV GNDFVVTLSE VSDVDDVLKR
160 170 180 190 200
LETVAKLGVP NYFGNQRFGN NGNNLQEAKR WGRDNVRSRN QNQRSLYLSA
210 220 230 240 250
ARSWIFNLIV SARLEQSLFD KVLLGDILFK GDEQLLVSAE NHADLQSQYD
260 270 280 290 300
AGDLVISGAL AGDNALPTQD DALALEQVFL DAEPDLMALI RGNRMRHDRR
310 320 330 340
AIALKPANLS WQVDGNNIIL TFSLDAGSFA TSIIRELVQE IAFEREF
Length:347
Mass (Da):38,554
Last modified:March 1, 2003 - v1
Checksum:i5B5B3ED1F99C1D59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA Translation: AAO10007.1
RefSeqiWP_011079517.1, NC_004459.3

Genome annotation databases

EnsemblBacteriaiAAO10007; AAO10007; VV1_1584
KEGGivvu:VV1_1584

Similar proteinsi

Entry informationi

Entry nameiTRUD_VIBVU
AccessioniPrimary (citable) accession number: Q8DC58
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: March 1, 2003
Last modified: February 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program