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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi16Divalent metal cationUniRule annotation1
Metal bindingi17Divalent metal cationUniRule annotation1
Metal bindingi47Divalent metal cationUniRule annotation1
Metal bindingi100Divalent metal cationUniRule annotation1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:VV1_1585
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001118511 – 2555'-nucleotidase SurEAdd BLAST255

Interactioni

Protein-protein interaction databases

STRINGi216895.VV1_1585.

Structurei

3D structure databases

ProteinModelPortaliQ8DC57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiNLNIPPC.
OrthoDBiPOG091H01CP.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DC57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDKQAKPLR ILLSNDDGVF AEGIRTLASE LRTLAEVIIV APDRNRSGAS
60 70 80 90 100
NSLTLEQPLR VTCVEENVYS VQGTPTDCVH FALNELLKND LPDLVLSGIN
110 120 130 140 150
HGANLGDDVL YSGTVAAAME GHFLGVQSIA FSLVGKTHFK TAATIAKRIV
160 170 180 190 200
EQHLAKPIPT NRLLNINIPD LPLEQLEEIR VTRLGARHHA ENMIKQLDPR
210 220 230 240 250
GHEIYWLGPP GKEQDAGEGT DFHAIEQGYV SITPLQVDLT AHESLRAMDT

WLKEK
Length:255
Mass (Da):28,061
Last modified:March 1, 2003 - v1
Checksum:i9954791F2595430B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA. Translation: AAO10008.1.
RefSeqiWP_011079518.1. NC_004459.3.

Genome annotation databases

EnsemblBacteriaiAAO10008; AAO10008; VV1_1585.
KEGGivvu:VV1_1585.
PATRICi20159951. VBIVibVul94426_1469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA. Translation: AAO10008.1.
RefSeqiWP_011079518.1. NC_004459.3.

3D structure databases

ProteinModelPortaliQ8DC57.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216895.VV1_1585.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO10008; AAO10008; VV1_1585.
KEGGivvu:VV1_1585.
PATRICi20159951. VBIVibVul94426_1469.

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiNLNIPPC.
OrthoDBiPOG091H01CP.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSURE_VIBVU
AccessioniPrimary (citable) accession number: Q8DC57
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.