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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:VV1_1819
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003665361 – 376Ribosomal RNA large subunit methyltransferase GAdd BLAST376

Structurei

3D structure databases

ProteinModelPortaliQ8DBJ8
SMRiQ8DBJ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J Bacteria
COG2813 LUCA
HOGENOMiHOG000246323
KOiK11391
OMAiNLQAWDA
OrthoDBiPOG091H05RK

Family and domain databases

HAMAPiMF_01859 23SrRNA_methyltr_G, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR013675 Mtase_sm_N
IPR017237 rRNA_m2G-MeTrfase_RsmD
IPR029063 SAM-dependent_MTases
IPR007848 Small_mtfrase_dom
PANTHERiPTHR18895:SF6 PTHR18895:SF6, 1 hit
PfamiView protein in Pfam
PF05175 MTS, 1 hit
PF08468 MTS_N, 1 hit
PIRSFiPIRSF037565 RRNA_m2G_Mtase_RsmD_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

Q8DBJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTELNLFDR QLTLFRYPNN ANETLQAWDA GDEYLINYVE ELALDTPQNI
60 70 80 90 100
LILNDHFGAL SCWFSAQHQV TMMSDSFISQ QGAKENLQRN QCREVKLLTT
110 120 130 140 150
LDAIPTETSL VLFQLPKNNR HLTWQLTQLR KTLSPDVPVV AVNKAKEIHT
160 170 180 190 200
STLKLFEKYL GTTKTSLAWK KHRLVFCQAD CAQMNDISPV TRWNVEEHKM
210 220 230 240 250
TLNNLPNVYS GESLDLGARF MLEHIPQDDN LKHIIDLGCG NGVLSVKAAQ
260 270 280 290 300
LNPKAKFTLV DESYMAIESA RLNLQENVTA SVDAEYIANN CLDGFAGEIA
310 320 330 340 350
DLILCNPPFH QQQAITDHIA WQMFCDAKRV LKRGGKLQVI GNRHLGYDGK
360 370
LKRLYGDKNV KLVASNSKFV ILQATK
Length:376
Mass (Da):42,546
Last modified:March 1, 2003 - v1
Checksum:i9A9063ED3745B1EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA Translation: AAO10225.1
RefSeqiWP_011079725.1, NC_004459.3

Genome annotation databases

EnsemblBacteriaiAAO10225; AAO10225; VV1_1819
GeneIDi2625400
KEGGivvu:VV1_1819

Similar proteinsi

Entry informationi

Entry nameiRLMG_VIBVU
AccessioniPrimary (citable) accession number: Q8DBJ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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