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Q8DAH8 (ACKA1_VIBVU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase 1
EC=2.7.2.1
Alternative name(s):
Acetokinase 1
Gene names
Name:ackA1
Ordered Locus Names:VV1_2221
OrganismVibrio vulnificus [Complete proteome] [HAMAP]
Taxonomic identifier672 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Acetate kinase 1 HAMAP MF_00020
PRO_0000107641

Sequences

Sequence LengthMass (Da)Tools
Q8DAH8 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 5295DC83097BBF86

FASTA39842,881
        10         20         30         40         50         60 
MSKLVLVLNC GSSSLKFAVV DAENGAEHLS GLAECLHLPE ARIKWKLDGK HEAQLGNGAA 

        70         80         90        100        110        120 
HEEALAFMVE TILASKPELS ENLAAIGHRV VHGGEQFTQS ALITDEVLKG IEDCATLAPL 

       130        140        150        160        170        180 
HNPAHIIGIK AAQKSFPALK NVAVFDTAFH QTMPEEAYLY ALPYNLYKEH GIRRYGMHGT 

       190        200        210        220        230        240 
SHLFITREVA SLLNKPVEEV NIINCHLGNG ASVCAVKNGQ SVDTSMGLTP LEGLVMGTRC 

       250        260        270        280        290        300 
GDIDPAIIFH LHDTLGYSVE KINTMLTKES GLAGLTEVTS DCRFVEDNYG QKEEATRAMD 

       310        320        330        340        350        360 
VFCHRLAKYV AGYTATLEGR LDAITFTGGI GENSAPIREM VLNRLGIFGI EVDSEANLKA 

       370        380        390 
RFGGEGVITT ANSRIPAMVI STNEELVIAE DTARLAGL

« Hide

References

[1]"Complete genome sequence of Vibrio vulnificus CMCP6."
Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.
Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CMCP6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016795 Genomic DNA. Translation: AAO10602.1.
RefSeqNP_761075.1. NC_004459.3.

3D structure databases

ProteinModelPortalQ8DAH8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1179103.
GenomeReviewsGene locus VV1_2221 in contig AE016795_GR.
KEGGvvu:VV1_2221.
PATRIC20161215. VBIVibVul94426_2086.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMAYLPEARI.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycVVUL216895:VV1_2221-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA1_VIBVU
AccessionPrimary (citable) accession number: Q8DAH8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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