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Q8DA38 (PNCB_VIBVU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:VV1_2372
OrganismVibrio vulnificus (strain CMCP6) [Complete proteome] [HAMAP]
Taxonomic identifier216895 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 437437Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205849

Sequences

Sequence LengthMass (Da)Tools
Q8DA38 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 6E1DB458931754A7

FASTA43750,001
        10         20         30         40         50         60 
MCAPLFQPAI IQSVLDLDVY KINMMQAAYR FYPQTQVRYE LIVRSDDNLS DLVEEVREEI 

        70         80         90        100        110        120 
NRLAELRFDA AQLAYLAEKA PYLTAEFLSY LETFRFHPQQ QVSVGIFRTA QGDCQLRVTI 

       130        140        150        160        170        180 
NGIWHETILY ETLVMSIISE LRNRRYWAQI PQSQLHKVLE DKLDFLDSEL KRRNITNFRF 

       190        200        210        220        230        240 
SEMGTRRRFS FAAQKTMLDV LRARVPELLL GTSNYHLAQE FNLTPIGTVA HEWTMAHQAL 

       250        260        270        280        290        300 
VAIQHSQRVA LDKWLEAFNG SLGIALTDTI GIDAFLSDFD LDKATAYAGV RHDSGSPFVW 

       310        320        330        340        350        360 
GDKIIAHYES LGIDPTTKTL IFTDGLDFAR ALDICEYFAG RAQISFGIGT FLANDMGNWT 

       370        380        390        400        410        420 
NDKGTRYQPI SMVVKMAECN GSPVAKISDE PEKAMCEDIF FLMNLKQRFG LEVDLDKAIE 

       430 
TLKQMKRQQK KRIQSVA 

« Hide

References

[1]"Complete genome sequence of Vibrio vulnificus CMCP6."
Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.
Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CMCP6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016795 Genomic DNA. Translation: AAO10746.1.
RefSeqNP_761219.1. NC_004459.3.

3D structure databases

ProteinModelPortalQ8DA38.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216895.VV1_2372.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO10746; AAO10746; VV1_2372.
GeneID1179247.
KEGGvvu:VV1_2372.
PATRIC20161519. VBIVibVul94426_2238.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycVVUL216895:GIYM-2123-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_VIBVU
AccessionPrimary (citable) accession number: Q8DA38
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways