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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciVVUL216895:G1GJ4-2849-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:VV1_2774
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003499781 – 364Ribosomal RNA large subunit methyltransferase FAdd BLAST364

Proteomic databases

PRIDEiQ8D935

Structurei

3D structure databases

ProteinModelPortaliQ8D935
SMRiQ8D935
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA Bacteria
COG3129 LUCA
HOGENOMiHOG000218605
KOiK06970
OMAiTEFHQGH
OrthoDBiPOG091H05H4

Family and domain databases

HAMAPiMF_01848 23SrRNA_methyltr_F, 1 hit
InterProiView protein in InterPro
IPR016909 rRNA_lsu_MeTfrase_F
IPR010286 rRNA_lsu_MeTfrase_F-like
IPR029063 SAM-dependent_MTases
PANTHERiPTHR13393 PTHR13393, 1 hit
PfamiView protein in Pfam
PF05971 Methyltransf_10, 1 hit
PIRSFiPIRSF029038 Mtase_YbiN_prd, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit

Sequencei

Sequence statusi: Complete.

Q8D935-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNKRKSAKP LEPAKRAPKP RTKKSRDLSA SESNCDFVKV TRAGLHSRNK
60 70 80 90 100
HQGRYDFAKL TQALPSLAPF VIKNPKGEAS ISFSDSTAVK MLNKALLSAY
110 120 130 140 150
YQVANWDIPA GYLCPPIPGR ADYIHRLAEL LEGEVKGKFP HEKVQALDIG
160 170 180 190 200
VGANAIYPII AICDYRWRYT GSDVDPKSIE SAQRIADSNP VLQGQLELKL
210 220 230 240 250
QDQSQHIFQG IIGPTDYFHV TTCNPPFHAS AQEAAFGTQR KLDNLAANRL
260 270 280 290 300
KKGVTAKAGS QKISKNKPIL NFGGQNSELW CQGGESSFLK RMANESERFA
310 320 330 340 350
HQVLWFSTLV SKKDNVRPLR KQLEKLGVRS IRVVEMSQGQ KVSRFVAWSF
360
MDKQQRGEWI KLRG
Length:364
Mass (Da):40,722
Last modified:March 1, 2003 - v1
Checksum:i75B257B095EFA6C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA Translation: AAO11116.1
RefSeqiWP_011080610.1, NC_004459.3

Genome annotation databases

EnsemblBacteriaiAAO11116; AAO11116; VV1_2774
KEGGivvu:VV1_2774

Similar proteinsi

Entry informationi

Entry nameiRLMF_VIBVU
AccessioniPrimary (citable) accession number: Q8D935
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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