Reviewed, UniProtKB/Swiss-Prot Q8D7K4 (ACKA2_VIBVU)

Names and origin

Protein names

Recommended name:
    Acetate kinase 2
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 2

Gene names

Name:	ackA2
Ordered Locus Names:	VV2_0148

Organism

Vibrio vulnificus [Complete proteome] [HAMAP]

Taxonomic identifier

672 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase 2 HAMAP MF_00020		PRO_0000107642

Sequences

	Sequence		Length	Mass (Da)
	Q8D7K4-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 338D8558CC8AF001	FASTA	397	42,595
	10 20 30 40 50 60 MSNSFVLVIN SGSSSLKFAV INSVTGEAVL SGLGECFGLE DARMGWKYSG EKTEIAIEGE 70 80 90 100 110 120 DNHHKIAIGK LVGLTEELGL TKDIVAVGHR IVHGGEKFTS TVRINEEVTA EIEKLADLAP 130 140 150 160 170 180 LHNPAGAIGI RAAMEAFPAL PQFAVFDTAF HQTMPKRAFT GAIANELYTD FGIRRYGFHG 190 200 210 220 230 240 TSHYFVSREA AKMLNKPIEE SSFISVHLGN GASVCAINNG ESVDTSMGFT PLSGLMMGTR 250 260 270 280 290 300 CGDLDPGIIE YLLKKGWSQE KVFNSLNKAS GFLGVSGLTS DARGILEAME QGHEGATLAF 310 320 330 340 350 360 QVFTYRVAKY IASYLAALDS FDGIIFTGGI GENSLPIRRE ILKNLKLLGF VEDEKGNEDA 370 380 390 RFGNAGVIAT SALLNAVAMV IPTNEEFVIA QQSVELL

References

[1]	"Complete genome sequence of Vibrio vulnificus CMCP6." Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E. Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CMCP6.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016796 Genomic DNA. Translation: AAO07121.1.
RefSeq	NP_762131.1.
3D structure databases
HSSP	HSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBase	Search...
Genome annotation databases
GeneID	1180172.
GenomeReviews	Gene locus VV2_0148 in contig AE016796_GR.
KEGG	vvu:VV2_0148.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8D7K4.
OMA	Q8D7K4. HESVLID.
Enzyme and pathway databases
BioCyc	VVUL216895:VV2_0148-MON.
BRENDA	2.7.2.1. 277169.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate_kin. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA2_VIBVU

Accession

Primary (citable) accession number: Q8D7K4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 23, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)