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Protein

Molybdenum import ATP-binding protein ModC

Gene

modC

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.UniRule annotation

Catalytic activityi

ATP + H2O + molybdate(Out) = ADP + phosphate + molybdate(In).UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi33 – 408ATPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Molybdenum, Nucleotide-binding

Enzyme and pathway databases

BioCyciVVUL216895:GIYM-3191-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Molybdenum import ATP-binding protein ModCUniRule annotation (EC:3.6.3.29UniRule annotation)
Gene namesi
Name:modCUniRule annotation
Ordered Locus Names:VV2_0327
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002275 Componenti: Chromosome 2

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 368368Molybdenum import ATP-binding protein ModCPRO_0000092561Add
BLAST

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).UniRule annotation

Protein-protein interaction databases

STRINGi216895.VV2_0327.

Structurei

3D structure databases

ProteinModelPortaliQ8D740.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 231231ABC transporterUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. [View classification]UniRule annotation
Contains 1 ABC transporter domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG4148.
KOiK02017.
OMAiKDELWAN.
OrthoDBiEOG664CG0.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015852. ABC_transpr_ModC.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR011868. ModC_ABC_ATP-bd.
IPR027417. P-loop_NTPase.
IPR005116. Transp-assoc_OB_typ1.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF03459. TOBE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02142. modC_ABC. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51241. MODC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8D740-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGLQVAFKQ TLGHVVFDIE LQLPSKGVSA IFGRSGAGKT SIINVISGLT
60 70 80 90 100
QPEQGRIALN SDVLFDSVLG INVPVHQRNI GYVFQDSRLF PHYHVEGNLK
110 120 130 140 150
YGVKQYDAEM FDKVVTLLAL QPLLKRYPAS LSGGEKQRVA IGRALLSSPK
160 170 180 190 200
ILLMDEPLAS LDMPRKKEVL PFLEKLSESF EIPIVYVTHS LQEILRLADH
210 220 230 240 250
LTVLDRGQIV ASGLLSEVWS SQAMRPWQSF SEQSTLFNAN IAEQHPQYAL
260 270 280 290 300
TRVMLSSTAS LWVQKIDAPL GSDIRLQVRA NDVSITLVQP QKTSIRNIIE
310 320 330 340 350
AKVERVEKRH PAEDKESIAV KLALTQDCFL WATITPWALA DLNLKQGDRV
360
FAQIKGVSVT QRDIALTH
Length:368
Mass (Da):40,963
Last modified:March 1, 2003 - v1
Checksum:i34630224037E0AE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016796 Genomic DNA. Translation: AAO07287.1.
RefSeqiNP_762297.1. NC_004460.2.
WP_011081288.1. NC_004460.2.

Genome annotation databases

EnsemblBacteriaiAAO07287; AAO07287; VV2_0327.
KEGGivvu:VV2_0327.
PATRICi20164054. VBIVibVul94426_3489.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016796 Genomic DNA. Translation: AAO07287.1.
RefSeqiNP_762297.1. NC_004460.2.
WP_011081288.1. NC_004460.2.

3D structure databases

ProteinModelPortaliQ8D740.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216895.VV2_0327.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO07287; AAO07287; VV2_0327.
KEGGivvu:VV2_0327.
PATRICi20164054. VBIVibVul94426_3489.

Phylogenomic databases

eggNOGiCOG4148.
KOiK02017.
OMAiKDELWAN.
OrthoDBiEOG664CG0.

Enzyme and pathway databases

BioCyciVVUL216895:GIYM-3191-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015852. ABC_transpr_ModC.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR011868. ModC_ABC_ATP-bd.
IPR027417. P-loop_NTPase.
IPR005116. Transp-assoc_OB_typ1.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF03459. TOBE. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02142. modC_ABC. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51241. MODC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Vibrio vulnificus CMCP6."
    Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CMCP6.

Entry informationi

Entry nameiMODC_VIBVU
AccessioniPrimary (citable) accession number: Q8D740
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: March 1, 2003
Last modified: May 27, 2015
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.