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Protein

Uronate isomerase

Gene

uxaC

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:VV2_1070
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001727921 – 470Uronate isomeraseAdd BLAST470

Proteomic databases

PRIDEiQ8D556.

Interactioni

Protein-protein interaction databases

STRINGi216895.VV2_1070.

Structurei

3D structure databases

ProteinModelPortaliQ8D556.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8D556-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNFLCEDFL LSNETARRLY HEHACHQPIY DYHCHLNPAE VAQNRQFDNL
60 70 80 90 100
GQIWLEGDHY KWRGMRSAGI EERLITGDAS DYDKYMAWAK TVPQTLGNPL
110 120 130 140 150
YHWTHLELRR PFGITNTLFS PDTADQIWHQ CNELLATPEF TARGIMQQMN
160 170 180 190 200
VVMAGTTDDP IDSLKHHKTI AEDDTFNVKV LPSWRPDKAF KIELDLFADY
210 220 230 240 250
MHKLGEVADI EIRRFDDLLS ALDKRLAHFD AHGCRAADHG IEIVRYAPIP
260 270 280 290 300
SEADLDVLLA RRLNGEVLSE LECAQFSTAV QVWLGKRYAQ LGWVMQLHIG
310 320 330 340 350
AQRNNSTRMF QLLGADAGFD SIGDRPFAFE LAHLLDEMDQ TNELPRTILY
360 370 380 390 400
CLNPRDNEMM ATMIGNFQGG GIAGKVQFGS GWWFNDQKDG MQRQMEQLSQ
410 420 430 440 450
LGLLSQFVGM LTDSRSFLSY TRHEYFRRIL CDMVGRWAEN GEVPNDLSLL
460 470
GPMVEDICFG NAKRYFEERV
Length:470
Mass (Da):54,023
Last modified:March 1, 2003 - v1
Checksum:iB32E80E3D98BD5BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016796 Genomic DNA. Translation: AAO07977.1.
RefSeqiWP_011081971.1. NC_004460.2.

Genome annotation databases

EnsemblBacteriaiAAO07977; AAO07977; VV2_1070.
KEGGivvu:VV2_1070.
PATRICi20165528. VBIVibVul94426_4221.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016796 Genomic DNA. Translation: AAO07977.1.
RefSeqiWP_011081971.1. NC_004460.2.

3D structure databases

ProteinModelPortaliQ8D556.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216895.VV2_1070.

Proteomic databases

PRIDEiQ8D556.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO07977; AAO07977; VV2_1070.
KEGGivvu:VV2_1070.
PATRICi20165528. VBIVibVul94426_4221.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_VIBVU
AccessioniPrimary (citable) accession number: Q8D556
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.