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Q8D4P0

- GLGB_VIBVU

UniProt

Q8D4P0 - GLGB_VIBVU

Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

    Catalytic activityi

    Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei396 – 3961NucleophileUniRule annotation
    Active sitei449 – 4491Proton donorUniRule annotation

    GO - Molecular functioni

    1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
    2. cation binding Source: InterPro
    3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

    Enzyme and pathway databases

    BioCyciVVUL216895:GIYM-4047-MONOMER.
    UniPathwayiUPA00164.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
    Alternative name(s):
    1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
    Alpha-(1->4)-glucan branching enzymeUniRule annotation
    Glycogen branching enzymeUniRule annotation
    Short name:
    BEUniRule annotation
    Gene namesi
    Name:glgBUniRule annotation
    Ordered Locus Names:VV2_1252
    OrganismiVibrio vulnificus (strain CMCP6)
    Taxonomic identifieri216895 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
    ProteomesiUP000002275: Chromosome 2

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7157151,4-alpha-glucan branching enzyme GlgBPRO_0000188762Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi216895.VV2_1252.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8D4P0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0296.
    HOGENOMiHOG000283037.
    KOiK00700.
    OMAiPIGVAYK.
    OrthoDBiEOG6JX7GT.

    Family and domain databases

    Gene3Di2.60.40.10. 2 hits.
    2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    HAMAPiMF_00685. GlgB.
    InterProiIPR006048. A-amylase_b_C.
    IPR006407. GlgB.
    IPR015902. Glyco_hydro_13.
    IPR013780. Glyco_hydro_13_b.
    IPR006047. Glyco_hydro_13_cat_dom.
    IPR004193. Glyco_hydro_13_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    [Graphical view]
    PANTHERiPTHR10357. PTHR10357. 1 hit.
    PfamiPF00128. Alpha-amylase. 1 hit.
    PF02806. Alpha-amylase_C. 1 hit.
    PF02922. CBM_48. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000463. GlgB. 1 hit.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF81296. SSF81296. 2 hits.
    TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8D4P0-1 [UniParc]FASTAAdd to Basket

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    MFEKLSQAAC SEPFAFLGPF IDPTQGALRV WMPGATGVAL VLEGQPRIAL    50
    EREKESAFIL KADLNLHLTH YQLAIDWNGV EQLVDDPYQY HGIYAEYDDL 100
    HTPKTMYQHM GSQFMTLERD GKSISGIRFL VYAPHATAVS LVGSFNDWDG 150
    RRHPMQRLDY GIWGLFIPDL AEGVSYKFEM KGPKGEGLPH KADPWGFYAE 200
    QYPSFASVTY DHARYQWQDA QWQTRPVTEK RKEALSFYEL HAGSWKRNEQ 250
    GEFLNYRELA AELVPYLVDM GYTHVELMPV SEHPFYGSWG YQPVGLFAPT 300
    SRYGSPDDFK FFVDACHQAG IGVVLDWVPA HFPSDDHGLA NFDGTPLFHD 350
    PDPRRGWHQD WNSFIYDLGR EQVRRFLVSN ALYWFEQFHI DGIRVDAVAS 400
    MLYLDYSRSH GQWIPNMDGG NENYDAIATL KWMNEEVYKY FPNAMTIAEE 450
    STAFPGVSAP TFMGGLGFGF KWNMGWMHDS LSYIKEEPVH RKYHHNTLTF 500
    PLVYAHSENY VLSLSHDEVV YGKGSIHNKM PGDEWQQTAN LRAYFGYMYG 550
    QPGKKLNFMG AEIGQTAEWN HDDQLQWFLL DFPRHQGVQA LTRDLNHLYR 600
    NQAALHDQDC IPAGFEWRLQ DAAEQSIIAH ERISEAGERI LVVSNFTPVP 650
    RDEFRLGVPN KGRYQLLLNT DDSKYAGSGY EVVVDAKSEA VVSEDLAQSI 700
    VLRLPPLSTL FYKLV 715
    Length:715
    Mass (Da):81,927
    Last modified:March 1, 2003 - v1
    Checksum:i304C61BECF5A5F43
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016796 Genomic DNA. Translation: AAO08146.1.
    RefSeqiNP_763156.1. NC_004460.2.

    Genome annotation databases

    EnsemblBacteriaiAAO08146; AAO08146; VV2_1252.
    GeneIDi1181202.
    KEGGivvu:VV2_1252.
    PATRICi20165886. VBIVibVul94426_4400.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016796 Genomic DNA. Translation: AAO08146.1 .
    RefSeqi NP_763156.1. NC_004460.2.

    3D structure databases

    ProteinModelPortali Q8D4P0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 216895.VV2_1252.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO08146 ; AAO08146 ; VV2_1252 .
    GeneIDi 1181202.
    KEGGi vvu:VV2_1252.
    PATRICi 20165886. VBIVibVul94426_4400.

    Phylogenomic databases

    eggNOGi COG0296.
    HOGENOMi HOG000283037.
    KOi K00700.
    OMAi PIGVAYK.
    OrthoDBi EOG6JX7GT.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci VVUL216895:GIYM-4047-MONOMER.

    Family and domain databases

    Gene3Di 2.60.40.10. 2 hits.
    2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    HAMAPi MF_00685. GlgB.
    InterProi IPR006048. A-amylase_b_C.
    IPR006407. GlgB.
    IPR015902. Glyco_hydro_13.
    IPR013780. Glyco_hydro_13_b.
    IPR006047. Glyco_hydro_13_cat_dom.
    IPR004193. Glyco_hydro_13_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    [Graphical view ]
    PANTHERi PTHR10357. PTHR10357. 1 hit.
    Pfami PF00128. Alpha-amylase. 1 hit.
    PF02806. Alpha-amylase_C. 1 hit.
    PF02922. CBM_48. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000463. GlgB. 1 hit.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF81296. SSF81296. 2 hits.
    TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Vibrio vulnificus CMCP6."
      Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.
      Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CMCP6.

    Entry informationi

    Entry nameiGLGB_VIBVU
    AccessioniPrimary (citable) accession number: Q8D4P0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 15, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3