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Q8D1V8

- G6PI_WIGBR

UniProt

Q8D1V8 - G6PI_WIGBR

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Wigglesworthia glossinidia brevipalpis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei355 – 3551Proton donorUniRule annotation
    Active sitei386 – 3861UniRule annotation
    Active sitei511 – 5111UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:WIGBR5980
    OrganismiWigglesworthia glossinidia brevipalpis
    Taxonomic identifieri36870 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeWigglesworthia
    ProteomesiUP000000562: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 548548Glucose-6-phosphate isomerasePRO_0000180767Add
    BLAST

    Proteomic databases

    PRIDEiQ8D1V8.

    Interactioni

    Protein-protein interaction databases

    STRINGi36870.WGLp598.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8D1V8.
    SMRiQ8D1V8. Positions 6-548.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8D1V8-1 [UniParc]FASTAAdd to Basket

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    MKNINPTKTK SWNLLKKHFN NMKKVNIKDL FEKDKNRFSS FSICFDDIIL    50
    IDYSKNIITK ETIKKLIQLA KECDLNNAIL SMFCGKKINY TENRAVLHTA 100
    LRNHKNISIE IDGINIIPKI KKVLNKMKNF CSDLIDGNWK GFTGERITHI 150
    VNIGIGGSDL GPYMVTEALK FYKNHLNVYF VSNIDGTHIT EILKYLSPKN 200
    TLFLIASKTF TTQETITNAY SAKDWFLKYA KDKKYLSRHF IALSSNIDEV 250
    KKFGINTENI FELWNWVGGR YSLWSCMGLS IALSIGFNNF EKLLRGAYAM 300
    DQHFLKQPFE KNIPIILGLI SIWYNNFFNF ETESILVYDQ YMHLFSSYFQ 350
    QVNMESNGKS IDRNGNLVNY QTGSILWGGY GTNSQHAFYQ LMHQGTKIVP 400
    CDFIVPIISH NPVSDHHQKL LANFFAQTKA LAFGKKSENN HIKLYKYDSN 450
    KIKILPFKIL PGNRPTNSIL IKEINPYNLG SLIAMYEHKI FTQGVVLNIN 500
    SFDQWGVELG KQLSKKLFSI LRKEKILNTS SYDSSTNGLI NFYKLWKK 548
    Length:548
    Mass (Da):63,293
    Last modified:March 1, 2003 - v1
    Checksum:iF41DC895019E1F09
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000021 Genomic DNA. Translation: BAC24744.1.
    RefSeqiNP_871601.1. NC_004344.2.

    Genome annotation databases

    EnsemblBacteriaiBAC24744; BAC24744; BAC24744.
    GeneIDi1257419.
    KEGGiwbr:WGLp598.
    PATRICi24025452. VBIWigGlo15804_0642.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000021 Genomic DNA. Translation: BAC24744.1 .
    RefSeqi NP_871601.1. NC_004344.2.

    3D structure databases

    ProteinModelPortali Q8D1V8.
    SMRi Q8D1V8. Positions 6-548.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 36870.WGLp598.

    Proteomic databases

    PRIDEi Q8D1V8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC24744 ; BAC24744 ; BAC24744 .
    GeneIDi 1257419.
    KEGGi wbr:WGLp598.
    PATRICi 24025452. VBIWigGlo15804_0642.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the endocellular obligate symbiont of tsetse flies, Wigglesworthia glossinidia."
      Akman L., Yamashita A., Watanabe H., Oshima K., Shiba T., Hattori M., Aksoy S.
      Nat. Genet. 32:402-407(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiG6PI_WIGBR
    AccessioniPrimary (citable) accession number: Q8D1V8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 23, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3