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Q8D1V8

- G6PI_WIGBR

UniProt

Q8D1V8 - G6PI_WIGBR

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Wigglesworthia glossinidia brevipalpis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donorUniRule annotation
Active sitei386 – 3861UniRule annotation
Active sitei511 – 5111UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:WIGBR5980
OrganismiWigglesworthia glossinidia brevipalpis
Taxonomic identifieri36870 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeWigglesworthia
ProteomesiUP000000562: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 548548Glucose-6-phosphate isomerasePRO_0000180767Add
BLAST

Proteomic databases

PRIDEiQ8D1V8.

Interactioni

Protein-protein interaction databases

STRINGi36870.WGLp598.

Structurei

3D structure databases

ProteinModelPortaliQ8D1V8.
SMRiQ8D1V8. Positions 6-548.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8D1V8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNINPTKTK SWNLLKKHFN NMKKVNIKDL FEKDKNRFSS FSICFDDIIL
60 70 80 90 100
IDYSKNIITK ETIKKLIQLA KECDLNNAIL SMFCGKKINY TENRAVLHTA
110 120 130 140 150
LRNHKNISIE IDGINIIPKI KKVLNKMKNF CSDLIDGNWK GFTGERITHI
160 170 180 190 200
VNIGIGGSDL GPYMVTEALK FYKNHLNVYF VSNIDGTHIT EILKYLSPKN
210 220 230 240 250
TLFLIASKTF TTQETITNAY SAKDWFLKYA KDKKYLSRHF IALSSNIDEV
260 270 280 290 300
KKFGINTENI FELWNWVGGR YSLWSCMGLS IALSIGFNNF EKLLRGAYAM
310 320 330 340 350
DQHFLKQPFE KNIPIILGLI SIWYNNFFNF ETESILVYDQ YMHLFSSYFQ
360 370 380 390 400
QVNMESNGKS IDRNGNLVNY QTGSILWGGY GTNSQHAFYQ LMHQGTKIVP
410 420 430 440 450
CDFIVPIISH NPVSDHHQKL LANFFAQTKA LAFGKKSENN HIKLYKYDSN
460 470 480 490 500
KIKILPFKIL PGNRPTNSIL IKEINPYNLG SLIAMYEHKI FTQGVVLNIN
510 520 530 540
SFDQWGVELG KQLSKKLFSI LRKEKILNTS SYDSSTNGLI NFYKLWKK
Length:548
Mass (Da):63,293
Last modified:March 1, 2003 - v1
Checksum:iF41DC895019E1F09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000021 Genomic DNA. Translation: BAC24744.1.
RefSeqiNP_871601.1. NC_004344.2.

Genome annotation databases

EnsemblBacteriaiBAC24744; BAC24744; BAC24744.
GeneIDi1257419.
KEGGiwbr:WGLp598.
PATRICi24025452. VBIWigGlo15804_0642.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000021 Genomic DNA. Translation: BAC24744.1 .
RefSeqi NP_871601.1. NC_004344.2.

3D structure databases

ProteinModelPortali Q8D1V8.
SMRi Q8D1V8. Positions 6-548.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 36870.WGLp598.

Proteomic databases

PRIDEi Q8D1V8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC24744 ; BAC24744 ; BAC24744 .
GeneIDi 1257419.
KEGGi wbr:WGLp598.
PATRICi 24025452. VBIWigGlo15804_0642.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular obligate symbiont of tsetse flies, Wigglesworthia glossinidia."
    Akman L., Yamashita A., Watanabe H., Oshima K., Shiba T., Hattori M., Aksoy S.
    Nat. Genet. 32:402-407(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiG6PI_WIGBR
AccessioniPrimary (citable) accession number: Q8D1V8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3