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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Wigglesworthia glossinidia brevipalpis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:WIGBR6040
OrganismiWigglesworthia glossinidia brevipalpis
Taxonomic identifieri36870 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeWigglesworthia
Proteomesi
  • UP000000562 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001287581 – 510Probable malate:quinone oxidoreductaseAdd BLAST510

Interactioni

Protein-protein interaction databases

STRINGi36870.WGLp604.

Structurei

3D structure databases

ProteinModelPortaliQ8D1V2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
KOiK00116.
OMAiEPIAATK.
OrthoDBiPOG091H0B7C.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR006231. MQO.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8D1V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKKNHEDSN SFKKYSAIKE NDSVDVVLIG SGIMSATLGI YLKLLEPNWI
60 70 80 90 100
IHSYERLNKV GQESSNAWNN AGTGHSAFCE LNYTSINKDG SINISKAIKV
110 120 130 140 150
NESFEISKQL WAYLIKEKIL VNSSSFINTV PHMSFVWGEN NINFLKKRFF
160 170 180 190 200
YLKQNALFKD MLYSENYDII KKWAPLIMEG RSINEKVAAT RMEIGTDVNF
210 220 230 240 250
GEITKQIFYY LKNKSNFFLY LNHDVIDIIR NKDKTWCLKV VDNILKKTIK
260 270 280 290 300
INSKYVFIGS GGGALKLLQK SKIEQSIGYA GFPVGGQFLV TKNKKLTNNH
310 320 330 340 350
QAKVYGKSPI GAPPMSVPHI DTRIINGEKV LLFGPFATFS SKFLKNGSYF
360 370 380 390 400
DLFSSLTKEN IIPILQVGIN NFNLVKYLIN QLLKSKRGKF NDLCKYLPTA
410 420 430 440 450
KMKDWSLITA GQRVQIIKKD IEKGGILEFG TEIINSKDCT LSALLGASPG
460 470 480 490 500
ASTSASTMLD LLKIMFYDKI NKSEWKSKLN KIFISYNKKI HESYEYTLEI
510
RNYTSKILSL
Length:510
Mass (Da):57,926
Last modified:March 1, 2003 - v1
Checksum:i47B5D88EFFD4BAAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000021 Genomic DNA. Translation: BAC24750.1.
RefSeqiWP_011070408.1. NC_004344.2.

Genome annotation databases

EnsemblBacteriaiBAC24750; BAC24750; BAC24750.
KEGGiwbr:yojH.

Similar proteinsi

Entry informationi

Entry nameiMQO_WIGBR
AccessioniPrimary (citable) accession number: Q8D1V2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families