ID   Q8D1M2_YERPE            Unreviewed;       438 AA.
AC   Q8D1M2; Q74Y66;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 116.
DE   SubName: Full=Secretion permease {ECO:0000313|EMBL:AAM83879.1};
GN   Name=acrA1 {ECO:0000313|EMBL:AAS60380.1};
GN   OrderedLocusNames=y0287 {ECO:0000313|EMBL:AAM83879.1}, YP_0101
GN   {ECO:0000313|EMBL:AAS60380.1};
OS   Yersinia pestis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632 {ECO:0000313|EMBL:AAM83879.1, ECO:0000313|Proteomes:UP000002490};
RN   [1] {ECO:0000313|EMBL:AAM83879.1, ECO:0000313|Proteomes:UP000002490}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM {ECO:0000313|EMBL:AAM83879.1}, and KIM10+ / Biovar
RC   Mediaevalis {ECO:0000313|Proteomes:UP000002490};
RX   PubMed=12142430; DOI=10.1128/JB.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G.III., Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plana G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [2] {ECO:0000313|EMBL:AAS60380.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=91001 {ECO:0000313|EMBL:AAS60380.1};
RA   Song Y., Tong Z., Wang L., Han Y., Zhang J., Pei D., Wang J., Zhou D.,
RA   Han Y., Pang X., Zhai J., Chen F., Qin H., Wang J., Li S., Guo Z., Ye C.,
RA   Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.;
RL   Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Proteomes:UP000001019}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis {ECO:0000313|Proteomes:UP000001019};
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
RN   [4] {ECO:0000313|EMBL:AAS60380.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=91001 {ECO:0000313|EMBL:AAS60380.1};
RA   Yiqing M.;
RT   "Reannotation of Yersinia pestis strain 91001 based on omics data.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; AE009952; AAM83879.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS60380.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8D1M2; -.
DR   IntAct; Q8D1M2; 3.
DR   DNASU; 1145234; -.
DR   EnsemblBacteria; AAS60380; AAS60380; YP_0101.
DR   KEGG; ypk:y0287; -.
DR   KEGG; ypm:YP_0101; -.
DR   HOGENOM; CLU_023976_4_0_6; -.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 2.40.50.100; -; 1.
DR   InterPro; IPR006144; Secretion_HlyD_CS.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR30386:SF27; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   Pfam; PF13437; HlyD_3; 1.
DR   PRINTS; PR01490; RTXTOXIND.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
DR   PROSITE; PS00543; HLYD_FAMILY; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          125..170
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   438 AA;  49703 MW;  B268F0C2ADEE85AA CRC64;
     MMGITERGMS SNQIFRRDAV EYIRTKWLGK ALLTSGYSTT FIAALCAIFL VLLITLIIYG
     TYTRRINVNG EVISQPHPIN IFSPQQGFIT KKWVEVGDIV RKGQHLYQID VSRTTFSGNV
     SLNSLEAINN QLSQIDSIIN NTQKNKELTL LNLRQQLAQY QKAHKKSQEL VDNAGKGMDD
     MRRTMASYGT YQRQGLITKD QLTNQRSLFY QQQNAFQSLN TQLIQESLQI AKLESEISTR
     ASDFDNDISQ YLFQKGDLKR QLAEVDASGM LLINSPSDGK IENMSVTQGQ MVNVNDSLVQ
     LTPSDNPYYC LVLWVPNNSV PYINTGDKVN IRYDAFPFEK FGQFPGRIIS ISNVPVSQQE
     IASYNIAPRL PNGGLIEPYY KVIVALDDIH FRYQSKPLML SNGLKANVTL FLEKRPLYQW
     MLSPFYDIKK SVTGPVNE
//