SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8CY39

- MURG_BRUSU

UniProt

Q8CY39 - MURG_BRUSU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene
murG, BR1431, BS1330_I1425
Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity.UniRule annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Source: UniProtKB-EC
  3. undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. lipid glycosylation Source: UniProtKB-HAMAP
  4. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
  5. regulation of cell shape Source: UniProtKB-KW
  6. UDP-N-acetylgalactosamine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC:2.4.1.227)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene namesi
Name:murG
Ordered Locus Names:BR1431, BS1330_I1425
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000824: Chromosome I, UP000007104: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 379379UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationPRO_0000109152Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204722.BR1431.

Structurei

3D structure databases

ProteinModelPortaliQ8CY39.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0707.
HOGENOMiHOG000218321.
KOiK02563.
OMAiPFIKDMA.
OrthoDBiEOG61VZFD.

Family and domain databases

HAMAPiMF_00033. MurG.
InterProiIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
PfamiPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01133. murG. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CY39-1 [UniParc]FASTAAdd to Basket

« Hide

MDNLANQGVI VLAAGGTGGH LFPAEALAHE LRARGWDVHL ATDARAQRFV    50
GAFAQDHVHV IRSATIAGRN PVALLKTFWS LWQGNLDSRK LFRRLKPKLV 100
VGFGGYPTLP PLYAASNMGI PTLIHEQNAV MGRANKGLAG RVKAIAGGFL 150
PENSGAYAAK TVITGNPVRP PVLVAAATPY TPAGKDDRFR LLVFGGSQGA 200
QFFSQAIPAA VALLPEHERA RLLITQQARK EDEASARQAY EKLGVPADVA 250
PFFNDMPARM ADAHFVIARS GASTVSEITV IGRPAMLVPF PHALDHDQAA 300
NAAALAAAGG AEVVRQADLS PQRLAEMLQS AMNEPERLEQ QAKAAKSVGK 350
PDAARLLADL AEAIVSGKTV QEFKEGNRP 379
Length:379
Mass (Da):40,236
Last modified:March 1, 2003 - v1
Checksum:i705EE98D96F30177
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN30344.1.
CP002997 Genomic DNA. Translation: AEM18760.1.
RefSeqiNP_698429.1. NC_004310.3.
YP_005616252.1. NC_017251.1.

Genome annotation databases

EnsemblBacteriaiAAN30344; AAN30344; BR1431.
AEM18760; AEM18760; BS1330_I1425.
GeneIDi1167113.
12138464.
KEGGibms:BR1431.
bsi:BS1330_I1425.
PATRICi17791221. VBIBruSui107850_1457.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014291 Genomic DNA. Translation: AAN30344.1 .
CP002997 Genomic DNA. Translation: AEM18760.1 .
RefSeqi NP_698429.1. NC_004310.3.
YP_005616252.1. NC_017251.1.

3D structure databases

ProteinModelPortali Q8CY39.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204722.BR1431.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN30344 ; AAN30344 ; BR1431 .
AEM18760 ; AEM18760 ; BS1330_I1425 .
GeneIDi 1167113.
12138464.
KEGGi bms:BR1431.
bsi:BS1330_I1425.
PATRICi 17791221. VBIBruSui107850_1457.

Phylogenomic databases

eggNOGi COG0707.
HOGENOMi HOG000218321.
KOi K02563.
OMAi PFIKDMA.
OrthoDBi EOG61VZFD.

Enzyme and pathway databases

UniPathwayi UPA00219 .

Family and domain databases

HAMAPi MF_00033. MurG.
InterProi IPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view ]
Pfami PF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01133. murG. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiMURG_BRUSU
AccessioniPrimary (citable) accession number: Q8CY39
Secondary accession number(s): G0KBJ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi