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Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1
Alternative name(s):
GroEL protein 1
Protein Cpn60 1
Gene namesi
Name:groL1
Synonyms:groEL1
Ordered Locus Names:CE0602
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000001409 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000633491 – 53760 kDa chaperonin 1Add BLAST537

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.

Protein-protein interaction databases

STRINGi196164.HMPREF0290_1129.

Structurei

3D structure databases

ProteinModelPortaliQ8CY27.
SMRiQ8CY27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiYWIASNA.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CY27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLIAFDQD AREGILRGVD ALANTVKVTL GPRGRNVVLD KAFGGPLVTN
60 70 80 90 100
DGVTIARDID VEDPFENLGA QLVKSVAVKT NDIAGDGTTT ATLLAQALIA
110 120 130 140 150
EGLRNVAAGA NPIELNKGIE AATQKTLDEL RARATPISAP QEVASVATVS
160 170 180 190 200
SRDEVVGKIV AEAMEKVGKD GVVTVEESQS LETTLDITEG ISFDKGYLSP
210 220 230 240 250
YFINDTDTQT AVLENPAILL VRNKISSLPD FLPLLEKIVE SNRPVLIIAE
260 270 280 290 300
DIEGEPLQTL VVNSIRKTIK AVAVKSPYFG DRRKAFMDDL AVVTNATVVD
310 320 330 340 350
PEVGINLSEA GVEVLGTARR VTVSKDETIL VDGAGDAEAV EARRQQIRRE
360 370 380 390 400
IETTDSTWDR EKAEERLAKL SGGVAVIRVG AATETEVNER KLRVEDAINA
410 420 430 440 450
ARAAAQEGII AGGGSALVQI AETLKAYAEE FEGDQKVGIR ALAAALSKPA
460 470 480 490 500
YWIAANAGLD GAVIVARIAD LPNNEGFNAA TLEYGNLVDQ GVIDPVKVTH
510 520 530
SAVVNASSVA RMVLTTEASI VDKPAEETAD HGHGHHH
Length:537
Mass (Da):56,803
Last modified:March 1, 2003 - v1
Checksum:iA1DB1DC927A15909
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC17412.1.
RefSeqiWP_006769721.1. NZ_GG700687.1.

Genome annotation databases

EnsemblBacteriaiBAC17412; BAC17412; BAC17412.
KEGGicef:CE0602.

Similar proteinsi

Entry informationi

Entry nameiCH601_COREF
AccessioniPrimary (citable) accession number: Q8CY27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2003
Last modified: November 22, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families