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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:CE2561
OrganismiCorynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Taxonomic identifieri196164 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000001409 Componenti: Chromosome

Subcellular locationi

Q8CY22:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000633501 – 54760 kDa chaperonin 2Add BLAST547

Proteomic databases

PRIDEiQ8CY22.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi196164.HMPREF0290_0309.

Structurei

3D structure databases

ProteinModelPortaliQ8CY22.
SMRiQ8CY22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CY22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKIIAFDEE ARRGLEKGLN TLADAVKVTL GPKGRNVVLE KAWGAPTITN
60 70 80 90 100
DGVTIAREIE LEDPYEKIGA ELVKEVAKKT DDVAGDGTTT ATVLAQALVK
110 120 130 140 150
EGLRNVAAGS NPMGIKRGIE QAVATVTEKL LESAKEVETE EQIAATAGIS
160 170 180 190 200
AADPAIGAQI AKAMYAVGGG KLNKDSVITV EESNTFGVEL EVTEGMRFDK
210 220 230 240 250
GYISGYFATD MERLEAVLED PYILLVSGKI SNIKDLLPLL EKVMQSGKPL
260 270 280 290 300
LIIAEDVEGE ALSTLVVNKI RGTFKSVAVK APGFGDRRKA QLQDIAILTG
310 320 330 340 350
GQVISEEVGL SLETADLPLL GQARKVVVTK DDTTIVDGAG SEEQIEGRVN
360 370 380 390 400
QIRAEIENSD SDYDREKLNE RLAKLAGGVA VLKVGAATEV ELKERKHRIE
410 420 430 440 450
DAVRNAKAAV EEGIVAGGGV ALIQAAHVLD NDLDLTGDEA TGVRIVRDAL
460 470 480 490 500
TAPLKQIAAN AGLEPGVVAD KVSRLPEGEG LNAATGEYVD LMAAGINDPV
510 520 530 540
KVTRSALQNA ASIAALFLTT EAVVADKPQP AGAAMPGADE MGGMGGF
Length:547
Mass (Da):57,288
Last modified:March 1, 2003 - v1
Checksum:iF508AFA2BC959E65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000035 Genomic DNA. Translation: BAC19371.1.
RefSeqiWP_006769076.1. NZ_GG700685.1.

Genome annotation databases

EnsemblBacteriaiBAC19371; BAC19371; BAC19371.
KEGGicef:CE2561.

Similar proteinsi

Entry informationi

Entry nameiCH602_COREF
AccessioniPrimary (citable) accession number: Q8CY22
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families