Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8CX33

- GLMS_SHEON

UniProt

Q8CX33 - GLMS_SHEON

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
Active sitei604 – 6041For Fru-6P isomerization activityUniRule annotation

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:SO_4741
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedUniRule annotation
Chaini2 – 609608Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135376Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi211586.SO_4741.

Structurei

3D structure databases

ProteinModelPortaliQ8CX33.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 218217Glutamine amidotransferase type-2UniRule annotationAdd
BLAST
Domaini286 – 426141SIS 1UniRule annotationAdd
BLAST
Domaini458 – 599142SIS 2UniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
Contains 2 SIS domains.UniRule annotation

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258898.
KOiK00820.
OMAiFYTHAGP.
OrthoDBiEOG6KT2Q1.
PhylomeDBiQ8CX33.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8CX33-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCGIVGAVAQ RDVAEILVEG LRRLEYRGYD SAGVAVIHNG ELNRTRRVGK
60 70 80 90 100
VQELSAALET DPLAGGTGIA HTRWATHGEP SERNAHPHLS EGDIAVVHNG
110 120 130 140 150
IIENHHKLRE MLKEHGYHFS SDTDTEVICH LVHHQLKTND SLLAAVQATV
160 170 180 190 200
KQLEGAYGTV VIDRRDSERM VVARSGSPLV IGFGLGENFV ASDQLALLPV
210 220 230 240 250
TRSFAFLEEG DVAEVTRRTV SIFDVHGNKV EREVKESEIT HDAGDKGEYR
260 270 280 290 300
HYMLKEIYEQ PLALTRTIEG RIANKQVLDT AFGDNAAEFL KDIKHVQIIA
310 320 330 340 350
CGTSYHAGMA ARYWLEDWAG VSCNVEIASE FRYRKSHLFP NSLLVTISQS
360 370 380 390 400
GETADTLAAM RLAKEMGYKA TLTICNAPGS SLVRESDMAY MMKAGAEIGV
410 420 430 440 450
ASTKAFTVQL AGLLMLTAVI GRHNGMSEQM QAEITQSLQS MPAKVEQALG
460 470 480 490 500
LDDAIAELAE DFADKHHALF LGRGDQYPIA MEGALKLKEI SYIHAEAYAS
510 520 530 540 550
GELKHGPLAL IDADMPVIVV APNNELLEKL KSNVEEVRAR GGLMYVFADV
560 570 580 590 600
DAEFESDDTM KVIPVPHCDI FMAPLIYTIP LQLLSYHVAL IKGTDVDQPR

NLAKSVTVE
Length:609
Mass (Da):66,729
Last modified:January 23, 2007 - v3
Checksum:iB56C0CB7700FE814
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN57700.1.
RefSeqiNP_720257.1. NC_004347.2.
WP_011074325.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN57700; AAN57700; SO_4741.
GeneIDi1172318.
KEGGison:SO_4741.
PATRICi23529151. VBISheOne101494_4598.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN57700.1 .
RefSeqi NP_720257.1. NC_004347.2.
WP_011074325.1. NC_004347.2.

3D structure databases

ProteinModelPortali Q8CX33.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 211586.SO_4741.

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN57700 ; AAN57700 ; SO_4741 .
GeneIDi 1172318.
KEGGi son:SO_4741.
PATRICi 23529151. VBISheOne101494_4598.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258898.
KOi K00820.
OMAi FYTHAGP.
OrthoDBi EOG6KT2Q1.
PhylomeDBi Q8CX33.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1.

Entry informationi

Entry nameiGLMS_SHEON
AccessioniPrimary (citable) accession number: Q8CX33
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 80 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3