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Q8CWX0

- GLGA_STRMU

UniProt

Q8CWX0 - GLGA_STRMU

Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

    Catalytic activityi

    ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ADP-glucoseUniRule annotation

    GO - Molecular functioni

    1. starch synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    BioCyciSMUT210007:GC7Z-1441-MONOMER.
    UniPathwayiUPA00164.

    Protein family/group databases

    CAZyiGT5. Glycosyltransferase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
    Alternative name(s):
    Starch [bacterial glycogen] synthaseUniRule annotation
    Gene namesi
    Name:glgAUniRule annotation
    Ordered Locus Names:SMU_1536
    OrganismiStreptococcus mutans serotype c (strain ATCC 700610 / UA159)
    Taxonomic identifieri210007 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002512: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 476476Glycogen synthasePRO_0000188648Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi210007.SMU.1536.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CWX0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0297.
    KOiK00703.
    OMAiICVISRI.
    OrthoDBiEOG6JTC6Z.
    PhylomeDBiQ8CWX0.

    Family and domain databases

    HAMAPiMF_00484. Glycogen_synth.
    InterProiIPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view]
    PfamiPF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02095. glgA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8CWX0-1 [UniParc]FASTAAdd to Basket

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    MKILFVAAEG APFAKTGGLG DVIGALPKSL VKNNNEVSVI LPYYDVVDAK    50
    FGDQIEDLFY FFTNVGWRRE YVGIKHIFRD GVDFYFIDNK HYFYRGQIYG 100
    EFDDGERFAY FQLAALEAME KIQFIPDILH VHDYHTAMIP YLLKEKYHWI 150
    NAYHGIKTVF TIHNIEFQGQ FNPSMLGELF GVGDERYRDG TLRWNDCLNW 200
    MKAAVLYADR VTTVSPSYAK EIMTPEFGKG LDQIMRMESG KLSGVVNGID 250
    TDLFDPETDP HLAVHFSKDD LSGKAKNKAA LQERVGLPVR EDVPLVGIVS 300
    RLTDQKGFQL VVDQLNTMMQ LDLQIVLLGT GYADFENAFA WFGHAYPDKM 350
    SANITFDLEL AQQIYAASDI FLMPSAFEPC GLSQMMAMRY GTLPLVHEVG 400
    GLRDTVIPYN EFEKTGTGFG FQDFSGYWLT KTLEAALDVY YNRKEDWKIL 450
    QKNAMTTDFS WDTASQSYEH LYKELA 476
    Length:476
    Mass (Da):54,312
    Last modified:March 1, 2003 - v1
    Checksum:iA2C0C078C3E3F3B4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014133 Genomic DNA. Translation: AAN59186.1.
    RefSeqiNP_721880.1. NC_004350.2.

    Genome annotation databases

    EnsemblBacteriaiAAN59186; AAN59186; SMU_1536.
    GeneIDi1028778.
    KEGGismu:SMU_1536.
    PATRICi19665079. VBIStrMut61772_1368.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014133 Genomic DNA. Translation: AAN59186.1 .
    RefSeqi NP_721880.1. NC_004350.2.

    3D structure databases

    ProteinModelPortali Q8CWX0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 210007.SMU.1536.

    Protein family/group databases

    CAZyi GT5. Glycosyltransferase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN59186 ; AAN59186 ; SMU_1536 .
    GeneIDi 1028778.
    KEGGi smu:SMU_1536.
    PATRICi 19665079. VBIStrMut61772_1368.

    Phylogenomic databases

    eggNOGi COG0297.
    KOi K00703.
    OMAi ICVISRI.
    OrthoDBi EOG6JTC6Z.
    PhylomeDBi Q8CWX0.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci SMUT210007:GC7Z-1441-MONOMER.

    Family and domain databases

    HAMAPi MF_00484. Glycogen_synth.
    InterProi IPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view ]
    Pfami PF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02095. glgA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700610 / UA159.

    Entry informationi

    Entry nameiGLGA_STRMU
    AccessioniPrimary (citable) accession number: Q8CWX0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 16, 2004
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3