Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8CWX0 (GLGA_STRMU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:SMU_1536
OrganismStreptococcus mutans serotype c (strain ATCC 700610 / UA159) [Complete proteome] [HAMAP]
Taxonomic identifier210007 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476Glycogen synthase HAMAP-Rule MF_00484
PRO_0000188648

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8CWX0 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: A2C0C078C3E3F3B4

FASTA47654,312
        10         20         30         40         50         60 
MKILFVAAEG APFAKTGGLG DVIGALPKSL VKNNNEVSVI LPYYDVVDAK FGDQIEDLFY 

        70         80         90        100        110        120 
FFTNVGWRRE YVGIKHIFRD GVDFYFIDNK HYFYRGQIYG EFDDGERFAY FQLAALEAME 

       130        140        150        160        170        180 
KIQFIPDILH VHDYHTAMIP YLLKEKYHWI NAYHGIKTVF TIHNIEFQGQ FNPSMLGELF 

       190        200        210        220        230        240 
GVGDERYRDG TLRWNDCLNW MKAAVLYADR VTTVSPSYAK EIMTPEFGKG LDQIMRMESG 

       250        260        270        280        290        300 
KLSGVVNGID TDLFDPETDP HLAVHFSKDD LSGKAKNKAA LQERVGLPVR EDVPLVGIVS 

       310        320        330        340        350        360 
RLTDQKGFQL VVDQLNTMMQ LDLQIVLLGT GYADFENAFA WFGHAYPDKM SANITFDLEL 

       370        380        390        400        410        420 
AQQIYAASDI FLMPSAFEPC GLSQMMAMRY GTLPLVHEVG GLRDTVIPYN EFEKTGTGFG 

       430        440        450        460        470 
FQDFSGYWLT KTLEAALDVY YNRKEDWKIL QKNAMTTDFS WDTASQSYEH LYKELA 

« Hide

References

[1]"Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen."
Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B., Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S., Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J.
Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700610 / UA159.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014133 Genomic DNA. Translation: AAN59186.1.
RefSeqNP_721880.1. NC_004350.2.

3D structure databases

ProteinModelPortalQ8CWX0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING210007.SMU.1536.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN59186; AAN59186; SMU_1536.
GeneID1028778.
KEGGsmu:SMU_1536.
PATRIC19665079. VBIStrMut61772_1368.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
KOK00703.
OMAVHCNDWQ.
OrthoDBEOG6JTC6Z.
ProtClustDBPRK00654.

Enzyme and pathway databases

BioCycSMUT210007:GC7Z-1441-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_STRMU
AccessionPrimary (citable) accession number: Q8CWX0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways