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Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciSMUT210007:GC7Z-1441-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:SMU_1536
OrganismiStreptococcus mutans serotype c (strain ATCC 700610 / UA159)
Taxonomic identifieri210007 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002512 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_0000188648Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi210007.SMU.1536.

Structurei

3D structure databases

ProteinModelPortaliQ8CWX0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.
PhylomeDBiQ8CWX0.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CWX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILFVAAEG APFAKTGGLG DVIGALPKSL VKNNNEVSVI LPYYDVVDAK
60 70 80 90 100
FGDQIEDLFY FFTNVGWRRE YVGIKHIFRD GVDFYFIDNK HYFYRGQIYG
110 120 130 140 150
EFDDGERFAY FQLAALEAME KIQFIPDILH VHDYHTAMIP YLLKEKYHWI
160 170 180 190 200
NAYHGIKTVF TIHNIEFQGQ FNPSMLGELF GVGDERYRDG TLRWNDCLNW
210 220 230 240 250
MKAAVLYADR VTTVSPSYAK EIMTPEFGKG LDQIMRMESG KLSGVVNGID
260 270 280 290 300
TDLFDPETDP HLAVHFSKDD LSGKAKNKAA LQERVGLPVR EDVPLVGIVS
310 320 330 340 350
RLTDQKGFQL VVDQLNTMMQ LDLQIVLLGT GYADFENAFA WFGHAYPDKM
360 370 380 390 400
SANITFDLEL AQQIYAASDI FLMPSAFEPC GLSQMMAMRY GTLPLVHEVG
410 420 430 440 450
GLRDTVIPYN EFEKTGTGFG FQDFSGYWLT KTLEAALDVY YNRKEDWKIL
460 470
QKNAMTTDFS WDTASQSYEH LYKELA
Length:476
Mass (Da):54,312
Last modified:March 1, 2003 - v1
Checksum:iA2C0C078C3E3F3B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014133 Genomic DNA. Translation: AAN59186.1.
RefSeqiNP_721880.1. NC_004350.2.
WP_002262948.1. NC_004350.2.

Genome annotation databases

EnsemblBacteriaiAAN59186; AAN59186; SMU_1536.
GeneIDi1028778.
KEGGismu:SMU_1536.
PATRICi19665079. VBIStrMut61772_1368.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014133 Genomic DNA. Translation: AAN59186.1.
RefSeqiNP_721880.1. NC_004350.2.
WP_002262948.1. NC_004350.2.

3D structure databases

ProteinModelPortaliQ8CWX0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi210007.SMU.1536.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN59186; AAN59186; SMU_1536.
GeneIDi1028778.
KEGGismu:SMU_1536.
PATRICi19665079. VBIStrMut61772_1368.

Phylogenomic databases

eggNOGiCOG0297.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.
PhylomeDBiQ8CWX0.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciSMUT210007:GC7Z-1441-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700610 / UA159.

Entry informationi

Entry nameiGLGA_STRMU
AccessioniPrimary (citable) accession number: Q8CWX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: March 1, 2003
Last modified: May 27, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.