Unreviewed, UniProtKB/TrEMBL Q8CWU3 (Q8CWU3_STRR6)

Names and origin

Protein names

Submitted name:
    Hyaluronate lyase (Hyaluronidase/hyase) EMBL AAK99090.1
    EC=4.2.2.1

Gene names

Name:	hysA EMBL AAK99090.1
Ordered Locus Names:	spr0286

Organism

Streptococcus pneumoniae (strain ATCC BAA-255 / R6) [Complete proteome] [HAMAP]

Taxonomic identifier

171101 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	1078 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

Ontologies

Keywords
Cellular component	Cell wall RuleBase RU000373V1 Secreted
Molecular function	Lyase
PTM	Peptidoglycan-anchor RuleBase RU000373V1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cell surface Inferred from electronic annotation. Source: InterPro extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8CWU3-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: B01A9A5034DD252C	FASTA	1,078	122,177
	10 20 30 40 50 60 MILQYVYWSV YMQTKTKKLI VSLSSLVLSG FLLNHYMTVG AEETTTNTIQ QSQKEVQYQQ 70 80 90 100 110 120 RDTKNLVENG DFGQTEDGSS PWTGSKAQGW SAWVDQKNSS ADASTRVIEA KDGAITISSP 130 140 150 160 170 180 EKLRAAVHRM VPIEAKKKYK LRFKIKTDNK VGIAKVRIIE ESGKDKRLWN SATTSGTKDW 190 200 210 220 230 240 QTIEADYSPT LDVDKIKLEL FYETGTGTVS FKDIELVEVA DQPSEDSQTD KQLEEKIDLP 250 260 270 280 290 300 IGKKHVFSLA DYTYKVENPD VASVKNGILE PLKEGTTNVI VSKDGKEVKK IPLKILASVK 310 320 330 340 350 360 DTYTDRLDDW NGIIAGNQYY DSKNEQMAKL NQELEGKVAD SLSSISSQAD RIYLWEKFSN 370 380 390 400 410 420 YKTSANLTAT YRKLEEMAKQ VTNPSSRYYQ DETVVRTVRD SMEWMHKHVY NSEKSIVGNW 430 440 450 460 470 480 WDYEIGTPRA INNTLSLMKE YFSDEEIKKY TDVIEKFVPD PEHFRKTTDN PFKALGGNLV 490 500 510 520 530 540 DMGRVKVIAG LLRKDDQEIS STIRSIEQVF KLVDQGEGFY QDGSYIDHTN VAYTGAYGNV 550 560 570 580 590 600 LIDGLSQLLP VIQKTKNPID KDKMQTMYHW IDKSFAPLLV NGELMDMSRG RSISRANSEG 610 620 630 640 650 660 HVAAVEVLRG IHRIADMSEG ETKQRLQSLV KTIVQSDSYY DVFKNLKTYK DISLMQSLLS 670 680 690 700 710 720 DAGVASVPRT SYLSAFNKMD KTAMYNAEKG FGFGLSLFSS RTLNYEHMNK ENKRGWYTSD 730 740 750 760 770 780 GMFYLYNGDL SHYSDGYWPT VNPYKMPGTT ETDAKRADSD TGKVLPSAFV GTSKLDDANA 790 800 810 820 830 840 TATMDFTNWN QTLTAHKSWF MLKDKIAFLG SNIQNTSTDT AATTIDQRKL ESSNPYKVYV 850 860 870 880 890 900 NDKEASLTEQ EKDYPETQSV FLESSDSKKN IGYFFFKKSS ISMSKALQKG AWKDINEGQS 910 920 930 940 950 960 DKEVENEFLT ISQAHKQNGD SYGYMLIPNV DRATFNQMIK ELESSLIENN ETLQSVYDAK 970 980 990 1000 1010 1020 QGVWGIVKYD DSVSTISNQF QVLKRGVYTI RKEGDEYKIA YYNPETQESA PDQEVFKKLE 1030 1040 1050 1060 1070 QAAQPQVQNS KEKEKSEEEK NHSDQKNLPQ TGEGQSILAS LGFLLLGAFY LFRRGKNN

References

[1]

"Genome of the bacterium Streptococcus pneumoniae strain R6." Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S., DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C., Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J., Lee L.N. , Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M., McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B., Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y., Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R., Rosteck P.R. Jr., Skatrud P.L., Glass J.I. J. Bacteriol. 183:5709-5717(2001) [PubMed: 11544234] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE007317 Genomic DNA. Translation: AAK99090.1.
PIR	F97907.
RefSeq	NP_357880.1.
3D structure databases
HSSP	HSSP built from PDB template 1OJN based on UniProtKB Q54873.
SMR	Q8CWU3. Positions 300-1018.
ModBase	Search...
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Genome annotation databases
GeneID	934705.
GenomeReviews	Gene locus spr0286 in contig AE007317_GR.
KEGG	spr:spr0286.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8CWU3.
OMA	Q8CWU3. GELMDMS.
Enzyme and pathway databases
BioCyc	SPNE171101:SPR0286-MON.
Family and domain databases
InterPro	IPR003305. CenC_carb_bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR019948. Gram-positive_anchor. IPR019931. LPXTG-motif_cell_wall_anchor. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
Pfam	PF02018. CBM_4_9. 1 hit. PF00746. Gram_pos_anchor. 1 hit. PF02278. Lyase_8. 1 hit. PF02884. Lyase_8_C. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01167. LPXTG_anchor. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8CWU3_STRR6

Accession

Primary (citable) accession number: Q8CWU3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)