Sialidase B (Neuraminidase B) - Streptococcus pneumoniae (strain ATCC BAA-255 / R6)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Sialidase B (Neuraminidase B) EMBL AAL00335.1
EC=3.2.1.18 EMBL AAL00335.1

Gene names

Name:	nanB EMBL AAL00335.1
Ordered Locus Names:	spr1531

Organism

Streptococcus pneumoniae (strain ATCC BAA-255 / R6)

Taxonomic identifier

171101 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	697 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Glycosidase EMBL AAL00335.1 Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	exo-alpha-(2->3)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->6)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->8)-sialidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q8CWP8 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 38766D2F6747AE53
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FASTA

697

77,664

        10         20         30         40         50         60 
MNKRGLYSKL GISVVGISLL MGVPALIHAN ELNYGQLSIS PIFQGGSYQL NNKSIDISPL 

        70         80         90        100        110        120 
LLDKLSGDSQ TVVMKFKADK PNSLQALFGL SNSKAGFKNN YFSIFMRDSG EIGVEIRDAQ 

       130        140        150        160        170        180 
KGINYLFSRP ASLWGKHKGQ AVENTLVFVS DSKDKTYTMY VNGIEVFSET VDTFLPISNI 

       190        200        210        220        230        240 
NGIDKATLGA VNREGKEHYL AKGSIDEISL FNKAISDQEV STIPLSNPFQ LIFQSGDSTQ 

       250        260        270        280        290        300 
ANYFRIPTLY TLSSGRVLSS IDARYGGTHD SKSKINIATS YSDDNGKTWS EPIFAMKFND 

       310        320        330        340        350        360 
YEEQLVYWPR DNKLKNSQIS GSASFIDSSI VEDKKSGKTI LLADVMPAGI GNNNANKADS 

       370        380        390        400        410        420 
GFKEINGHYY LKLKKNGDND FRYTVRENGV VYDETTNKPT NYTINDKYEV LEGGKSLTVE 

       430        440        450        460        470        480 
QYSVDFDSGS LRERHNGKQV PMNVFYKDSL FKVTPTNYIA MTTSQNRGES WEQFKLLPPF 

       490        500        510        520        530        540 
LGEKHNGTYL CPGQGLALKS SNRLIFATYT SGELTYLISD DSGQTWKKSS ASIPFENATA 

       550        560        570        580        590        600 
EAQMVELRDG VIRTFFRTTT GKIAYMTSRD SGETWSEVSY IDGIQQTSYG TQVSAIKYSQ 

       610        620        630        640        650        660 
LIDGKEAVIL STPNSRSGRK GGQLVVGLVN KEDDSIDWKY HYDIDLPSYG YAYSAITELP 

       670        680        690 
NHHIGVLFEK YDSWSRNELH LSNVVQYIDL EINDLTK

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References

[1]

"Genome of the bacterium Streptococcus pneumoniae strain R6."
Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S., DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C., Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J., Lee L.N.

Glass J.I.
J. Bacteriol. 183:5709-5717(2001) [PubMed: 11544234] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-255 / R6.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE007317 Genomic DNA. Translation: AAL00335.1.
PIR	B98063.
RefSeq	NP_359124.1. NC_003098.1.
3D structure databases
HSSP	HSSP built from PDB template 2SLI based on UniProtKB Q27701.
ProteinModelPortal	Q8CWP8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8CWP8.
Protein family/group databases
CAZy	CBM40. Carbohydrate-Binding Module Family 40. GH33. Glycoside Hydrolase Family 33.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000014806; EBSTRP00000014202; EBSTRG00000014806.
GeneID	933504.
GenomeReviews	Gene locus spr1531 in contig AE007317_GR.
KEGG	spr:spr1531.
PATRIC	19703075. VBIStrPne107296_1651.
Phylogenomic databases
eggNOG	COG4409.
GeneTree	EBGT00050000026665.
HOGENOM	HBG702051.
OMA	QEVSNIP.
ProtClustDB	CLSK560057.
Enzyme and pathway databases
BioCyc	SPNE171101:SPR1531-MONOMER.
Family and domain databases
InterPro	IPR002860. BNR_rpt. IPR008985. ConA-like_lec_gl. IPR013320. ConA-like_subgrp. IPR004124. Glyco_hydro_33_N. IPR011040. Neuraminidase. IPR023364. Trans_sialidase_dom3. [Graphical view]
Gene3D	G3DSA:2.60.120.200. ConA_like_subgrp. 1 hit. G3DSA:2.40.220.10. G3DSA:2.40.220.10. 1 hit. G3DSA:2.120.10.10. Neuraminidase. 2 hits.
KO	K01186.
Pfam	PF02012. BNR. 4 hits. PF02973. Sialidase. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit. SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8CWP8_STRR6

Accession

Primary (citable) accession number: Q8CWP8

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Preferred order of sections

Names and origin

Protein attributes

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information