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Q8CV87

- GLSA_OCEIH

UniProt

Q8CV87 - GLSA_OCEIH

Protein

Glutaminase

Gene

glsA

Organism
Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei77 – 771SubstrateUniRule annotation
    Binding sitei129 – 1291SubstrateUniRule annotation
    Binding sitei173 – 1731SubstrateUniRule annotation
    Binding sitei180 – 1801SubstrateUniRule annotation
    Binding sitei204 – 2041SubstrateUniRule annotation
    Binding sitei256 – 2561SubstrateUniRule annotation
    Binding sitei274 – 2741Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciOIHE221109:GI2A-933-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:OB0870
    OrganismiOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
    Taxonomic identifieri221109 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
    ProteomesiUP000000822: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 331331GlutaminasePRO_0000110614Add
    BLAST

    Proteomic databases

    PRIDEiQ8CV87.

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi221109.OB0870.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CV87.
    SMRiQ8CV87. Positions 21-331.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiMSIAVWS.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8CV87-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVQGSVNLNT ERGKEWLQDY VDNWVNFYQK QTDEGKVASY IPRLEHADPN    50
    ALGISIIGKN GTVIRSGDTD LEFSIQSISK VLSFIVACME RGLSYVLQRV 100
    DVEPTGESFN SIMHLEINQP KKPFNPLVNS GAITVSSLLN GRTSDQKLEP 150
    LYQLLEKILG HRPEIDVEVY VSERDTSMRN RAIGYYLLEE GYLESDLSIT 200
    LETYFKHCSL NVTVDDLAMI GLVLSNDGVH PNTDEPLIPK QIARVAKSLM 250
    LTCGMYDASG KFASYVGIPA KSGVSGGILA VVPPRVRDQN LPFLEGCGIG 300
    VFGPALDKQG NSIAGIKLLR HIANQWDLSL F 331
    Length:331
    Mass (Da):36,507
    Last modified:March 1, 2003 - v1
    Checksum:iBE3AF061D2DC229F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000028 Genomic DNA. Translation: BAC12826.1.
    RefSeqiNP_691791.1. NC_004193.1.
    WP_011065276.1. NC_004193.1.

    Genome annotation databases

    EnsemblBacteriaiBAC12826; BAC12826; BAC12826.
    GeneIDi1016494.
    KEGGioih:OB0870.
    PATRICi22792704. VBIOceIhe82024_0887.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000028 Genomic DNA. Translation: BAC12826.1 .
    RefSeqi NP_691791.1. NC_004193.1.
    WP_011065276.1. NC_004193.1.

    3D structure databases

    ProteinModelPortali Q8CV87.
    SMRi Q8CV87. Positions 21-331.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 221109.OB0870.

    Proteomic databases

    PRIDEi Q8CV87.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC12826 ; BAC12826 ; BAC12826 .
    GeneIDi 1016494.
    KEGGi oih:OB0870.
    PATRICi 22792704. VBIOceIhe82024_0887.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi MSIAVWS.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci OIHE221109:GI2A-933-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
      Takami H., Takaki Y., Uchiyama I.
      Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

    Entry informationi

    Entry nameiGLSA_OCEIH
    AccessioniPrimary (citable) accession number: Q8CV87
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 24, 2004
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3