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Q8CV87

- GLSA_OCEIH

UniProt

Q8CV87 - GLSA_OCEIH

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Protein

Glutaminase

Gene
glsA, OB0870
Organism
Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei77 – 771Substrate By similarity
Binding sitei129 – 1291Substrate By similarity
Binding sitei173 – 1731Substrate By similarity
Binding sitei180 – 1801Substrate By similarity
Binding sitei204 – 2041Substrate By similarity
Binding sitei256 – 2561Substrate By similarity
Binding sitei274 – 2741Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciOIHE221109:GI2A-933-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:OB0870
OrganismiOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
Taxonomic identifieri221109 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
ProteomesiUP000000822: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 331331GlutaminaseUniRule annotationPRO_0000110614Add
BLAST

Proteomic databases

PRIDEiQ8CV87.

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi221109.OB0870.

Structurei

3D structure databases

ProteinModelPortaliQ8CV87.
SMRiQ8CV87. Positions 21-331.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CV87-1 [UniParc]FASTAAdd to Basket

« Hide

MVQGSVNLNT ERGKEWLQDY VDNWVNFYQK QTDEGKVASY IPRLEHADPN    50
ALGISIIGKN GTVIRSGDTD LEFSIQSISK VLSFIVACME RGLSYVLQRV 100
DVEPTGESFN SIMHLEINQP KKPFNPLVNS GAITVSSLLN GRTSDQKLEP 150
LYQLLEKILG HRPEIDVEVY VSERDTSMRN RAIGYYLLEE GYLESDLSIT 200
LETYFKHCSL NVTVDDLAMI GLVLSNDGVH PNTDEPLIPK QIARVAKSLM 250
LTCGMYDASG KFASYVGIPA KSGVSGGILA VVPPRVRDQN LPFLEGCGIG 300
VFGPALDKQG NSIAGIKLLR HIANQWDLSL F 331
Length:331
Mass (Da):36,507
Last modified:March 1, 2003 - v1
Checksum:iBE3AF061D2DC229F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000028 Genomic DNA. Translation: BAC12826.1.
RefSeqiNP_691791.1. NC_004193.1.
WP_011065276.1. NC_004193.1.

Genome annotation databases

EnsemblBacteriaiBAC12826; BAC12826; BAC12826.
GeneIDi1016494.
KEGGioih:OB0870.
PATRICi22792704. VBIOceIhe82024_0887.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000028 Genomic DNA. Translation: BAC12826.1 .
RefSeqi NP_691791.1. NC_004193.1.
WP_011065276.1. NC_004193.1.

3D structure databases

ProteinModelPortali Q8CV87.
SMRi Q8CV87. Positions 21-331.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 221109.OB0870.

Proteomic databases

PRIDEi Q8CV87.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC12826 ; BAC12826 ; BAC12826 .
GeneIDi 1016494.
KEGGi oih:OB0870.
PATRICi 22792704. VBIOceIhe82024_0887.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci OIHE221109:GI2A-933-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
    Takami H., Takaki Y., Uchiyama I.
    Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Entry informationi

Entry nameiGLSA_OCEIH
AccessioniPrimary (citable) accession number: Q8CV87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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