Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8CV87 (GLSA_OCEIH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:OB0870
OrganismOceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]
Taxonomic identifier221109 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 331331Glutaminase HAMAP-Rule MF_00313
PRO_0000110614

Sites

Binding site771Substrate By similarity
Binding site1291Substrate By similarity
Binding site1731Substrate By similarity
Binding site1801Substrate By similarity
Binding site2041Substrate By similarity
Binding site2561Substrate By similarity
Binding site2741Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8CV87 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: BE3AF061D2DC229F

FASTA33136,507
        10         20         30         40         50         60 
MVQGSVNLNT ERGKEWLQDY VDNWVNFYQK QTDEGKVASY IPRLEHADPN ALGISIIGKN 

        70         80         90        100        110        120 
GTVIRSGDTD LEFSIQSISK VLSFIVACME RGLSYVLQRV DVEPTGESFN SIMHLEINQP 

       130        140        150        160        170        180 
KKPFNPLVNS GAITVSSLLN GRTSDQKLEP LYQLLEKILG HRPEIDVEVY VSERDTSMRN 

       190        200        210        220        230        240 
RAIGYYLLEE GYLESDLSIT LETYFKHCSL NVTVDDLAMI GLVLSNDGVH PNTDEPLIPK 

       250        260        270        280        290        300 
QIARVAKSLM LTCGMYDASG KFASYVGIPA KSGVSGGILA VVPPRVRDQN LPFLEGCGIG 

       310        320        330 
VFGPALDKQG NSIAGIKLLR HIANQWDLSL F 

« Hide

References

[1]"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments."
Takami H., Takaki Y., Uchiyama I.
Nucleic Acids Res. 30:3927-3935(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000028 Genomic DNA. Translation: BAC12826.1.
RefSeqNP_691791.1. NC_004193.1.

3D structure databases

ProteinModelPortalQ8CV87.
SMRQ8CV87. Positions 21-331.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING221109.OB0870.

Proteomic databases

PRIDEQ8CV87.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC12826; BAC12826; BAC12826.
GeneID1016494.
KEGGoih:OB0870.
PATRIC22792704. VBIOceIhe82024_0887.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAVNSIMAT.
OrthoDBEOG6N94BK.
ProtClustDBPRK12357.

Enzyme and pathway databases

BioCycOIHE221109:GI2A-933-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_OCEIH
AccessionPrimary (citable) accession number: Q8CV87
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families