Q8CV11 (MQO_OCEIH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	OB0946

Organism

Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) [Complete proteome] [HAMAP]

Taxonomic identifier

221109 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Oceanobacillus

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 502	502	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000128725

Sequences

	Sequence		Length	Mass (Da)
	Q8CV11 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 83625CF42D1515C8	FASTA	502	56,073
	10 20 30 40 50 60 MSNKHTQADV ILIGAGIMSA TLGSLLKELS PNLEIRVFEK LENPGEESSN EWNNAGTGHS 70 80 90 100 110 120 ALCELNYTSE RTDGSIDINK AVKVNEQFQL SRQFWSYLVN RNLIRNPEDF IRALPHISLV 130 140 150 160 170 180 QGEDNVTFLR KRFKALVNHP LFNGMEFSDD NEKLKEWMPL IMDKRDTNEP IAATKIDSGT 190 200 210 220 230 240 DVNFGALTRL LFQEFDHKGI DVNYNHSVED IKRNSEGLWE VKVHDMNDEK IEYHTAKFVF 250 260 270 280 290 300 IGAGGGSLPL LQKTGIKESK HIGGFPVSGL FMVCNNPEVI EQHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRFIDG KKSLLFGPFA GFSPKFLKTG SLFDLMHSVK SDNLFTMLSA GMKELPLTKY 370 380 390 400 410 420 LIQQVVLSNE KRMEELREFI PNAQSKDWDI VIAGQRVQVI KDTEDGGKGT LQFGTEVVCG 430 440 450 460 470 480 EDGTMAALLG ASPGASTAVH VMLEVIQKCF PEHLQEWEPK IKEMIPSYGI ALSENPELYK 490 500 EIEVSIEKAL GLKNEEPMVI PS

References

[1]

"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments." Takami H., Takaki Y., Uchiyama I. Nucleic Acids Res. 30:3927-3935(2002) [PubMed: 12235376] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14371 / JCM 11309 / KCTC 3954 / HTE831.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000028 Genomic DNA. Translation: BAC12902.1.
RefSeq	NP_691867.1. NC_004193.1.
3D structure databases
ProteinModelPortal	Q8CV11.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1016695.
GenomeReviews	Gene locus OB0946 in contig BA000028_GR.
KEGG	oih:OB0946.
NMPDR	fig|221109.1.peg.948.
PATRIC	22792892. VBIOceIhe82024_0964.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	KKWVPLM.
PhylomeDB	Q8CV11.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	OIHE221109:OB0946-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_OCEIH

Accession

Primary (citable) accession number: Q8CV11

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program