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Protein

Putative D-threonate 4-phosphate dehydrogenase

Gene

OB1013

Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).By similarity

Catalytic activityi

4-phospho-D-threonate + NAD+ = glycerone phosphate + CO2 + NADH.By similarity

Cofactori

a divalent metal cationBy similarityNote: Binds 1 divalent metal cation per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140SubstrateBy similarity1
Binding sitei141SubstrateBy similarity1
Metal bindingi170Divalent metal cation; shared with dimeric partnerBy similarity1
Metal bindingi214Divalent metal cation; shared with dimeric partnerBy similarity1
Metal bindingi270Divalent metal cation; shared with dimeric partnerBy similarity1
Binding sitei278SubstrateBy similarity1
Binding sitei287SubstrateBy similarity1
Binding sitei296SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processCarbohydrate metabolism
LigandMetal-binding, NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Putative D-threonate 4-phosphate dehydrogenaseBy similarity (EC:1.1.1.408By similarity)
Gene namesi
Ordered Locus Names:OB1013
OrganismiOceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Taxonomic identifieri221109 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
Proteomesi
  • UP000000822 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001888131 – 332Putative D-threonate 4-phosphate dehydrogenaseAdd BLAST332

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi221109.OB1013.

Structurei

3D structure databases

ProteinModelPortaliQ8CUU4.
SMRiQ8CUU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PdxA family. PdxA2 subfamily.Curated

Phylogenomic databases

eggNOGiENOG4105CEZ. Bacteria.
COG1995. LUCA.
HOGENOMiHOG000221591.
KOiK22024.
OMAiGHLYPGH.
OrthoDBiPOG091H03XD.

Family and domain databases

InterProiView protein in InterPro
IPR005255. PdxA.
PANTHERiPTHR30004. PTHR30004. 1 hit.
PfamiView protein in Pfam
PF04166. PdxA. 1 hit.
TIGRFAMsiTIGR00557. pdxA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CUU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKPIIGIT MGDAAGVGPE IIIKSLRNRE LYEQAHPIVI GDTKMLERAA
60 70 80 90 100
KILDVDVSFD KKTKDEELMD TEFGKITCID LDILPEDLAY GEVSPVSGNA
110 120 130 140 150
AFEYLRMAIE LANEGKIQAI CTAPLNKEAL QKGGHMYPGH TEILAELTNT
160 170 180 190 200
EEFSMMLSSP KLKVIHVTTH VGLIQAIQMI KPERVHKVIQ LAHETLSNSG
210 220 230 240 250
IKNPKIGVCG INPHAGENGL FGNGEEEEKI IPAIQQAVKE GINVEGPLPA
260 270 280 290 300
DTLFFRAQRG DFDIVVAMYH DQGHGPIKVL GLEAGVNITV GLPIIRTSVD
310 320 330
HGTAFDIAGK GIVDERSMLE ALHQAIELAP TK
Length:332
Mass (Da):36,017
Last modified:March 1, 2003 - v1
Checksum:iED62C9CA66FCB51A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000028 Genomic DNA. Translation: BAC12969.1.
RefSeqiWP_011065416.1. NC_004193.1.

Genome annotation databases

EnsemblBacteriaiBAC12969; BAC12969; BAC12969.
KEGGioih:OB1013.

Similar proteinsi

Entry informationi

Entry nameiPDXA2_OCEIH
AccessioniPrimary (citable) accession number: Q8CUU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families