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Protein

Adenine deaminase

Gene

ade

Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese

Enzyme and pathway databases

BioCyciOIHE221109:G1G3F-1109-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Synonyms:adeC
Ordered Locus Names:OB1030
OrganismiOceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Taxonomic identifieri221109 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeOceanobacillus
Proteomesi
  • UP000000822 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001424301 – 582Adenine deaminaseAdd BLAST582

Interactioni

Protein-protein interaction databases

STRINGi221109.OB1030

Structurei

3D structure databases

ProteinModelPortaliQ8CUS7
SMRiQ8CUS7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN Bacteria
COG1001 LUCA
HOGENOMiHOG000276949
KOiK01486
OMAiHEIANVM
OrthoDBiPOG091H00I8

Family and domain databases

CDDicd01295 AdeC, 1 hit
Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR01178 ade, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CUS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSTIEQLKH RIAVASKRKP AELVIKNAEV LNVFTGDWKK TDVAIADGYI
60 70 80 90 100
AGLGNYEGLQ TVDATGKKIV PGLINGHIHI ESTMLTPREF SKVMLKHGVT
110 120 130 140 150
TAITDPHEIA NVAGTDGLEY MLNASDALPM NIFVNMPSSV PATQFEHNGA
160 170 180 190 200
QLDAKDISSY FQNPNVLGLA EVMDFPSVAN ADQKMLEKIV STIQHGGIID
210 220 230 240 250
GHAAGLSKED LNIYMAAGIR NDHESVSAQE GKDRLEAGMY LMIREGTVAK
260 270 280 290 300
DLEALLPIIN DKNARRCIFV TDDMLLDDLV ENGDIDHIIR KAIQLGLDPV
310 320 330 340 350
MAYQMATLNT AECFGLRELG AVAPGYIADF LILNDENQVD IHQVYKNGKC
360 370 380 390 400
VVDEGEINQS YFAASLTYDA TTLPKPRIQQ LKASDFSIDL TDDYCNIIEI
410 420 430 440 450
VPNKIITNHV CERVEVKEGK FVPSVDKDQL LIAVVERHKG LGYIGKGIVK
460 470 480 490 500
GFKMKEGAIA TSVAHDSHNF VVVGTSEEEM LSAIKKVEQL DGGLVVTKRK
510 520 530 540 550
QVKAHLALPI GGLMSDKDYL DAYEEVLKLN HVAVENGIPS NFNPFLTLSF
560 570 580
LTLPVIPTLK VTDQGLFDFK TFSHINVEVE EK
Length:582
Mass (Da):63,824
Last modified:March 1, 2003 - v1
Checksum:i1D9A5B9F3445C273
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000028 Genomic DNA Translation: BAC12986.1
RefSeqiWP_011065432.1, NC_004193.1

Genome annotation databases

EnsemblBacteriaiBAC12986; BAC12986; BAC12986
KEGGioih:OB1030

Similar proteinsi

Entry informationi

Entry nameiADEC_OCEIH
AccessioniPrimary (citable) accession number: Q8CUS7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health