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Q8CTA4 (CSD_STAES) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable cysteine desulfurase
EC=2.8.1.7
Gene names
Name:csd
Ordered Locus Names:SE_0608
OrganismStaphylococcus epidermidis (strain ATCC 12228) [Complete proteome] [HAMAP]
Taxonomic identifier176280 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length413 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine By similarity.

Catalytic activity

L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

Cofactor

Pyridoxal phosphate By similarity.

Sequence similarities

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcysteine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functioncysteine desulfurase activity

Inferred from electronic annotation. Source: EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 413413Probable cysteine desulfurase
PRO_0000150315

Sites

Active site3681Cysteine persulfide intermediate By similarity

Amino acid modifications

Modified residue2291N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8CTA4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 0F29E092C37F272E

FASTA41346,021
        10         20         30         40         50         60 
MAEHSFDVKA VIKDFPILEQ KVNNKRLAYL DSTATSQTPV QVLNVLDDYY KRYNSNVHRG 

        70         80         90        100        110        120 
VHTLGSLATD GYENARETVR RFINAKYFEE IIFTRGTTAS INIVAHSYGD ANISEGDEIV 

       130        140        150        160        170        180 
VTEMEHHANI VPWQQLAKRK NATLKFIPMT KDGELQLDDI KATINDKTKI VAIAHVSNVL 

       190        200        210        220        230        240 
GTINDVKTIA KIAHEHGAVI SVDGAQSAPH MALDMQDIDA DFYSFSGHKM LGPTGIGVLY 

       250        260        270        280        290        300 
GKRELLQNME PVEFGGDMID FVSKYDSTWA DLPTKFEAGT PLIAQAIGLA EAIHYIENLG 

       310        320        330        340        350        360 
FNAIHQHEKE LTEYAYEQML TIDGLEIYGP PKDRRAGVIT FNLADIHPHD VATAVDTEGV 

       370        380        390        400        410 
AVRAGHHCAQ PLMKWLGVSS TARASFYVYN TKEDVDQLVQ ALKQTKEFFS YEF

« Hide

References

[1]"Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 12228.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE015929 Genomic DNA. Translation: AAO04205.1.
RefSeqNP_764163.1. NC_004461.1.

3D structure databases

ProteinModelPortalQ8CTA4.
ModBaseSearch...

Protein-protein interaction databases

STRING176280.SE0608.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO04205; AAO04205; SE_0608.
GeneID1057832.
KEGGsep:SE0608.
PATRIC19607003. VBIStaEpi113981_0579.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0520.
KOK11717.
OMAHEVEELG.
ProtClustDBCLSK884944.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR010970. Cys_dSase_SufS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01979. sufS. 1 hit.
PROSITEPS00595. AA_TRANSFER_CLASS_5. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCSD_STAES
AccessionPrimary (citable) accession number: Q8CTA4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: March 1, 2003
Last modified: May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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