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Q8CT80

- G6PI_STAES

UniProt

Q8CT80 - G6PI_STAES

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei285 – 2851Proton donorUniRule annotation
Active sitei306 – 3061UniRule annotation
Active sitei420 – 4201UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSEPI176280:GCDG-661-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:SE_0658
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001411: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 443443Glucose-6-phosphate isomerasePRO_0000180732Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi176280.SE0658.

Structurei

3D structure databases

ProteinModelPortaliQ8CT80.
SMRiQ8CT80. Positions 4-443.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiGVESYKR.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CT80-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTHIQLDYGK TLEFFDKHEL DQQKDIVKTI HQTIHKGTGA GNDFLGWLDL
60 70 80 90 100
PVDYDKEEFS RIVEASKRIK SNSDVLVVIG IGGSYLGARA AIEMLTSSFR
110 120 130 140 150
TNTEYPEIVF VGNHLSSSYT KELLDYLQGK DFSVNVISKS GTTTEPAVAF
160 170 180 190 200
RLFKQLVEEK YGKDEAKKRI FATTDKSKGA LKQLADNEGY ETFVVPDDVG
210 220 230 240 250
GRYSVLTAVG LLPIATAGIN IESIMIGAAK AREELSSDDL DQNIAYQYAT
260 270 280 290 300
IRNILYSKGY TTEMLINYEP SMQYFNEWWK QLYGESEGKD FKGIYPSSAN
310 320 330 340 350
YTTDLHSLGQ YVQEGRRFLF ETVVKVNHPK HDIKIEEDAD DLDGLNYLAG
360 370 380 390 400
KSIDEVNTKA FEGTLLAHTD GGVPNIVVNI PQLDEETFGY VVYFFELACA
410 420 430 440
MSGYQLGVNP FNQPGVEAYK QNMFALLGKP GFEDKKKELE NRL
Length:443
Mass (Da):49,708
Last modified:March 1, 2003 - v1
Checksum:i7FC5A79606E5A5D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA. Translation: AAO04255.1.
RefSeqiNP_764213.1. NC_004461.1.

Genome annotation databases

EnsemblBacteriaiAAO04255; AAO04255; SE_0658.
GeneIDi1055836.
KEGGisep:SE0658.
PATRICi19607109. VBIStaEpi113981_0632.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA. Translation: AAO04255.1 .
RefSeqi NP_764213.1. NC_004461.1.

3D structure databases

ProteinModelPortali Q8CT80.
SMRi Q8CT80. Positions 4-443.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 176280.SE0658.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO04255 ; AAO04255 ; SE_0658 .
GeneIDi 1055836.
KEGGi sep:SE0658.
PATRICi 19607109. VBIStaEpi113981_0632.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi GVESYKR.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci SEPI176280:GCDG-661-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
    Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
    Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12228.

Entry informationi

Entry nameiG6PI_STAES
AccessioniPrimary (citable) accession number: Q8CT80
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3