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Q8CSN5

- TRPF_STAES

UniProt

Q8CSN5 - TRPF_STAES

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSEPI176280:GCDG-1058-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
    Short name:
    PRAIUniRule annotation
    Gene namesi
    Name:trpFUniRule annotation
    Ordered Locus Names:SE_1052
    OrganismiStaphylococcus epidermidis (strain ATCC 12228)
    Taxonomic identifieri176280 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000001411: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 207207N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154382Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi176280.SE1052.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CSN5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0135.
    KOiK01817.
    OMAiLAVIQCH.
    OrthoDBiEOG6N94DF.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8CSN5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIVKFCGFKT ESDIKKIKKL EVDAVGFIHY PDSKRHVSLK QLKYLAKIVP    50
    DHIEKVVVVV NPQMSTIKRI INQTDINTIQ LHGNESIQLI RNIKKLNSKI 100
    RIIKAIPATR NLNNNIQKYK DEIDMFIIDT PSITYGGTGQ SFDWKLLKKI 150
    KGVDFLIAGG LDFEKIKRLE IYSFGQCGYD ISTGIESHNE KDFNKMTRIL 200
    KFLKGDE 207
    Length:207
    Mass (Da):23,785
    Last modified:March 1, 2003 - v1
    Checksum:i7337A1DF18A49B82
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO04649.1.
    RefSeqiNP_764607.1. NC_004461.1.

    Genome annotation databases

    EnsemblBacteriaiAAO04649; AAO04649; SE_1052.
    GeneIDi1056552.
    KEGGisep:SE1052.
    PATRICi19607910. VBIStaEpi113981_1028.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO04649.1 .
    RefSeqi NP_764607.1. NC_004461.1.

    3D structure databases

    ProteinModelPortali Q8CSN5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 176280.SE1052.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO04649 ; AAO04649 ; SE_1052 .
    GeneIDi 1056552.
    KEGGi sep:SE1052.
    PATRICi 19607910. VBIStaEpi113981_1028.

    Phylogenomic databases

    eggNOGi COG0135.
    KOi K01817.
    OMAi LAVIQCH.
    OrthoDBi EOG6N94DF.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci SEPI176280:GCDG-1058-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
      Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
      Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 12228.

    Entry informationi

    Entry nameiTRPF_STAES
    AccessioniPrimary (citable) accession number: Q8CSN5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 25, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3