Q8CQ62 (PTAS_STAES) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	SE_0359

Organism

Staphylococcus epidermidis (strain ATCC 12228) [Complete proteome] [HAMAP]

Taxonomic identifier

176280 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 329	329	Phosphate acetyltransferase		PRO_0000179146

Sequences

	Sequence		Length	Mass (Da)
	Q8CQ62 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 2B49E15055B99C0A	FASTA	329	35,088
	10 20 30 40 50 60 MADLLSVLQD KLSGKNVKIV LPEGEDERVL IAATQLQKTD YVSPIVLGNE DNIKSLASKH 70 80 90 100 110 120 ALDLTQIEII DPATSELKDE LVDAFVERRK GKATKEQAVE LLDNVNYFGT MLVYTGKAEG 130 140 150 160 170 180 LVSGAAHSTG DTVRPALQII KTKPGVSRTS GIFFMIKGDE QYIFGDCAIN PELDAQGLAE 190 200 210 220 230 240 IAVESAKSAQ SFGMDPKVAM LSFSTKGSAK SDDVTKVQEA LKLAQEKAEA DQLDHVVIDG 250 260 270 280 290 300 EFQFDAAIVP SVAEKKAPGA KIQGDANVFV FPSLEAGNIG YKIAQRLGGY DAVGPVLQGL 310 320 NSPVNDLSRG CSTEDVYNLS IITAAQALQ

References

[1]

"Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)." Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M. Mol. Microbiol. 49:1577-1593(2003) [PubMed: 12950922] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 12228.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015929 Genomic DNA. Translation: AAO03956.1.
RefSeq	NP_763914.1. NC_004461.1.
3D structure databases
ProteinModelPortal	Q8CQ62.
SMR	Q8CQ62. Positions 1-328.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8CQ62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000040029; EBSTAP00000038662; EBSTAG00000040027.
GeneID	1056781.
GenomeReviews	Gene locus SE_0359 in contig AE015929_GR.
KEGG	sep:SE0359.
PATRIC	19606511. VBIStaEpi113981_0334.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0280.
GeneTree	EBGT00050000025364.
HOGENOM	HBG576804.
OMA	GCSTEDV.
PhylomeDB	Q8CQ62.
ProtClustDB	PRK09653.
Enzyme and pathway databases
BioCyc	SEPI176280:SE_0359-MONOMER.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K00625.
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTAS_STAES

Accession

Primary (citable) accession number: Q8CQ62

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program