Q8CPR5 (Q8CPR5_STAES) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADPH] PIRNR PIRNR000094
Short name=ENR PIRNR PIRNR000094
EC=1.3.1.10 PIRNR PIRNR000094

Gene names

Ordered Locus Names:

SE_0712

Organism

Staphylococcus epidermidis (strain ATCC 12228) [Complete proteome] [HAMAP]

Taxonomic identifier

176280 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADPH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: InterPro enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	157	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	Q8CPR5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: F684FC82A7910B0E	FASTA	256	27,988
	10 20 30 40 50 60 MLNLENKTYV IMGIANKRSI AFGVAKVLDR LGAKLVFTYR KERSRKELEK LLEQLNQSEH 70 80 90 100 110 120 HLYEIDVQND EDIINGFSQI GKDVGQIDGV YHSIAFANME DLRGRFSETS REGFLLAQEI 130 140 150 160 170 180 SSYSLTLVAH EAKKLMPEGG SIVATTYIGG EAAVQNYNVM GVAKASLEAN VKYLALDLGE 190 200 210 220 230 240 DNIRVNAISA GPIRTLSAKG VGGFNTILKE IEARAPLKRN VDQEEVGKTA AYLLSDLSSG 250 VTGENIHVDG GFHAIK

References

[1]

"Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)." Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M. Mol. Microbiol. 49:1577-1593(2003) [PubMed: 12950922] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015929 Genomic DNA. Translation: AAO04309.1.
RefSeq	NP_764267.1. NC_004461.1.
3D structure databases
HSSP	HSSP built from PDB template 1DFI based on UniProtKB P29132.
ProteinModelPortal	Q8CPR5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8CPR5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000040404; EBSTAP00000039037; EBSTAG00000040402.
GeneID	1055765.
GenomeReviews	Gene locus SE_0712 in contig AE015929_GR.
KEGG	sep:SE0712.
PATRIC	19607219. VBIStaEpi113981_0686.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
GeneTree	EBGT00050000023865.
HOGENOM	HBG750976.
OMA	KKWDGLD.
PhylomeDB	Q8CPR5.
ProtClustDB	PRK08594.
Enzyme and pathway databases
BioCyc	SEPI176280:SE_0712-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

Q8CPR5_STAES

Accession

Primary (citable) accession number: Q8CPR5

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)