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Q8CPE6

- GLPD_STAES

UniProt

Q8CPE6 - GLPD_STAES

Protein

Aerobic glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

    Cofactori

    FAD.By similarity

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi21 – 4929FADSequence AnalysisAdd
    BLAST

    GO - Molecular functioni

    1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycerol-3-phosphate metabolic process Source: InterPro
    2. glycerol catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycerol metabolism

    Keywords - Ligandi

    FAD, Flavoprotein

    Enzyme and pathway databases

    BioCyciSEPI176280:GCDG-985-MONOMER.
    UniPathwayiUPA00618; UER00674.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aerobic glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
    Gene namesi
    Name:glpD
    Ordered Locus Names:SE_0979
    OrganismiStaphylococcus epidermidis (strain ATCC 12228)
    Taxonomic identifieri176280 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000001411: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. glycerol-3-phosphate dehydrogenase complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 557557Aerobic glycerol-3-phosphate dehydrogenasePRO_0000270066Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi176280.SE0979.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CPE6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0578.
    KOiK00111.
    OMAiYAKVDSF.
    OrthoDBiEOG651SR7.

    Family and domain databases

    InterProiIPR006076. FAD-dep_OxRdtase.
    IPR000447. G3P_DH_FAD-dep.
    [Graphical view]
    PfamiPF01266. DAO. 1 hit.
    [Graphical view]
    PRINTSiPR01001. FADG3PDH.
    PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
    PS00978. FAD_G3PDH_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8CPE6-1 [UniParc]FASTAAdd to Basket

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    MSLSTLKRDH IKKNLRDTEY DVVIVGGGIT GAGIALDASN RGMKVALVEM    50
    QDFAQGTSSR STKLVHGGLR YLKQLQVGVV AETGKERAIV YENGPHVTTP 100
    EWMLLPMHKG GTFGKFSTSI GLAMYDRLAG VKKSERKKML SKQETLNKEP 150
    LVKRDGLKGG GYYVEYRTDD ARLTIEVMKK AAENGAEILN YTKSEHFTYD 200
    SNKKVNGIEV LDMIDGETYA IKAKKVINAS GPWVDEVRSG DYARNNKQLR 250
    LTKGVHVVID QSKFPLGQAV YFDTEKDGRM IFAIPREGKA YVGTTDTFYD 300
    NEKATPLTTQ EDRDYLINAI NYMFPTVNVK DEDIESTWAG IRPLILEKGK 350
    DPSEISRKDE VWEGESGLLT IAGGKLTGYR HMALEIVDLL AKRLKQEYGL 400
    KFESCATKNL KISGGDVGGS KNFEHFVEQK VDAAKGFGID EDVARRLASK 450
    YGSNVDQLFN IAQTAPYHDS KLPLEIYVEL VYSIQQEMVY KPTDFLVRRS 500
    GKLYFNIQDV LDYKNAVIDV MADMLNYSET QKEAYTEEVE VAIDEARTGN 550
    DQPATKA 557
    Length:557
    Mass (Da):62,276
    Last modified:March 1, 2003 - v1
    Checksum:i6F6044C656324F7C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO04576.1.
    RefSeqiNP_764534.1. NC_004461.1.

    Genome annotation databases

    EnsemblBacteriaiAAO04576; AAO04576; SE_0979.
    GeneIDi1057632.
    KEGGisep:SE0979.
    PATRICi19607760. VBIStaEpi113981_0953.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO04576.1 .
    RefSeqi NP_764534.1. NC_004461.1.

    3D structure databases

    ProteinModelPortali Q8CPE6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 176280.SE0979.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO04576 ; AAO04576 ; SE_0979 .
    GeneIDi 1057632.
    KEGGi sep:SE0979.
    PATRICi 19607760. VBIStaEpi113981_0953.

    Phylogenomic databases

    eggNOGi COG0578.
    KOi K00111.
    OMAi YAKVDSF.
    OrthoDBi EOG651SR7.

    Enzyme and pathway databases

    UniPathwayi UPA00618 ; UER00674 .
    BioCyci SEPI176280:GCDG-985-MONOMER.

    Family and domain databases

    InterProi IPR006076. FAD-dep_OxRdtase.
    IPR000447. G3P_DH_FAD-dep.
    [Graphical view ]
    Pfami PF01266. DAO. 1 hit.
    [Graphical view ]
    PRINTSi PR01001. FADG3PDH.
    PROSITEi PS00977. FAD_G3PDH_1. 1 hit.
    PS00978. FAD_G3PDH_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
      Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
      Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 12228.

    Entry informationi

    Entry nameiGLPD_STAES
    AccessioniPrimary (citable) accession number: Q8CPE6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 9, 2007
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3