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Q8CPE6

- GLPD_STAES

UniProt

Q8CPE6 - GLPD_STAES

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Protein

Aerobic glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

FAD.By similarity

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 4929FADSequence AnalysisAdd
BLAST

GO - Molecular functioni

  1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
  2. glycerol catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycerol metabolism

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciSEPI176280:GCDG-985-MONOMER.
UniPathwayiUPA00618; UER00674.

Names & Taxonomyi

Protein namesi
Recommended name:
Aerobic glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:SE_0979
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001411: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 557557Aerobic glycerol-3-phosphate dehydrogenasePRO_0000270066Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi176280.SE0979.

Structurei

3D structure databases

ProteinModelPortaliQ8CPE6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0578.
KOiK00111.
OMAiYAKVDSF.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CPE6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLSTLKRDH IKKNLRDTEY DVVIVGGGIT GAGIALDASN RGMKVALVEM
60 70 80 90 100
QDFAQGTSSR STKLVHGGLR YLKQLQVGVV AETGKERAIV YENGPHVTTP
110 120 130 140 150
EWMLLPMHKG GTFGKFSTSI GLAMYDRLAG VKKSERKKML SKQETLNKEP
160 170 180 190 200
LVKRDGLKGG GYYVEYRTDD ARLTIEVMKK AAENGAEILN YTKSEHFTYD
210 220 230 240 250
SNKKVNGIEV LDMIDGETYA IKAKKVINAS GPWVDEVRSG DYARNNKQLR
260 270 280 290 300
LTKGVHVVID QSKFPLGQAV YFDTEKDGRM IFAIPREGKA YVGTTDTFYD
310 320 330 340 350
NEKATPLTTQ EDRDYLINAI NYMFPTVNVK DEDIESTWAG IRPLILEKGK
360 370 380 390 400
DPSEISRKDE VWEGESGLLT IAGGKLTGYR HMALEIVDLL AKRLKQEYGL
410 420 430 440 450
KFESCATKNL KISGGDVGGS KNFEHFVEQK VDAAKGFGID EDVARRLASK
460 470 480 490 500
YGSNVDQLFN IAQTAPYHDS KLPLEIYVEL VYSIQQEMVY KPTDFLVRRS
510 520 530 540 550
GKLYFNIQDV LDYKNAVIDV MADMLNYSET QKEAYTEEVE VAIDEARTGN

DQPATKA
Length:557
Mass (Da):62,276
Last modified:March 1, 2003 - v1
Checksum:i6F6044C656324F7C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015929 Genomic DNA. Translation: AAO04576.1.
RefSeqiNP_764534.1. NC_004461.1.

Genome annotation databases

EnsemblBacteriaiAAO04576; AAO04576; SE_0979.
GeneIDi1057632.
KEGGisep:SE0979.
PATRICi19607760. VBIStaEpi113981_0953.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015929 Genomic DNA. Translation: AAO04576.1 .
RefSeqi NP_764534.1. NC_004461.1.

3D structure databases

ProteinModelPortali Q8CPE6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 176280.SE0979.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO04576 ; AAO04576 ; SE_0979 .
GeneIDi 1057632.
KEGGi sep:SE0979.
PATRICi 19607760. VBIStaEpi113981_0953.

Phylogenomic databases

eggNOGi COG0578.
KOi K00111.
OMAi YAKVDSF.
OrthoDBi EOG651SR7.

Enzyme and pathway databases

UniPathwayi UPA00618 ; UER00674 .
BioCyci SEPI176280:GCDG-985-MONOMER.

Family and domain databases

InterProi IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view ]
Pfami PF01266. DAO. 1 hit.
[Graphical view ]
PRINTSi PR01001. FADG3PDH.
PROSITEi PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
    Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
    Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12228.

Entry informationi

Entry nameiGLPD_STAES
AccessioniPrimary (citable) accession number: Q8CPE6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3