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Protein

Catalase

Gene

katA

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.By similarity

Catalytic activityi

2 H2O2 = O2 + 2 H2O.PROSITE-ProRule annotation

Cofactori

hemeBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei56PROSITE-ProRule annotation1
Active sitei129PROSITE-ProRule annotation1
Metal bindingi339Iron (heme axial ligand)By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciSEPI176280:G1G05-1022-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase (EC:1.11.1.6)
Gene namesi
Name:katA
Ordered Locus Names:SE_1016
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000001411 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000850051 – 504CatalaseAdd BLAST504

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi176280.SE1016

Structurei

3D structure databases

ProteinModelPortaliQ8CPD0
SMRiQ8CPD0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.Curated

Phylogenomic databases

eggNOGiENOG4105CH6 Bacteria
COG0753 LUCA
KOiK03781
OMAiHADFGRM

Family and domain databases

Gene3Di2.40.180.10, 1 hit
InterProiView protein in InterPro
IPR018028 Catalase
IPR024708 Catalase_AS
IPR024711 Catalase_clade1/3
IPR011614 Catalase_core
IPR037060 Catalase_core_sf
IPR002226 Catalase_haem_BS
IPR010582 Catalase_immune_responsive
IPR020835 Catalase_sf
PANTHERiPTHR11465 PTHR11465, 1 hit
PfamiView protein in Pfam
PF00199 Catalase, 1 hit
PF06628 Catalase-rel, 1 hit
PIRSFiPIRSF038928 Catalase_clade1-3, 1 hit
PRINTSiPR00067 CATALASE
SMARTiView protein in SMART
SM01060 Catalase, 1 hit
SUPFAMiSSF56634 SSF56634, 1 hit
PROSITEiView protein in PROSITE
PS00437 CATALASE_1, 1 hit
PS00438 CATALASE_2, 1 hit
PS51402 CATALASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CPD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKQDGKLTG LFGAPVSDRE NSMTAGQRGP LLMQDVYYLE QISHFDREVI
60 70 80 90 100
PERRMHAKGS GAFGTFTVTN DITQYTNAKI FSEVGKQTEM FARFSTVSGE
110 120 130 140 150
RGAADLERDI RGFALKFYTE DGNWDLVGNN TPVFFFRDPK LFISLNRAVK
160 170 180 190 200
RDPRTNMRSA QNNWDFWTGL PEALHQVTIL MSDRGMPKGF RNMHGFGSHT
210 220 230 240 250
YSMYNDKGER VWVKYHFRTQ QGIENYTDEE AAKIVGMDRD SSQRDLYNAI
260 270 280 290 300
ENGDYPKWKM YIQVMTEEQA KNHPDNPFDL TKVWYKKDYP LIEVGEFELN
310 320 330 340 350
RNPENYFLDV EQAAFTPTNI VPGLDYSPDK MLQGRLFSYG DAQRYRLGVN
360 370 380 390 400
HWQIPVNQPK GVGVENLCPF SRDGQMRFLD NNQGGGPHYY PNNQGIYESQ
410 420 430 440 450
PEHKKPPFPT DGDGYEYNYR QDDDNYFEQP GKLFRLQSED AKERIFTNTA
460 470 480 490 500
NAMDGVSKDV KVRHIRHCYK ADPEYGKGVA KALGIDINQI DLETNQDETY

ENFK
Length:504
Mass (Da):58,213
Last modified:March 1, 2003 - v1
Checksum:i10A1D718AF5A6DBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA Translation: AAO04613.1
RefSeqiNP_764571.1, NC_004461.1
WP_001831169.1, NC_004461.1

Genome annotation databases

EnsemblBacteriaiAAO04613; AAO04613; SE_1016
GeneIDi1056574
KEGGisep:SE1016
PATRICifig|176280.10.peg.991

Similar proteinsi

Entry informationi

Entry nameiCATA_STAES
AccessioniPrimary (citable) accession number: Q8CPD0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health