Reviewed,
UniProtKB/Swiss-Prot Q8CPB5 (TYRA_STAES)
Last modified
June 16, 2009.
Version 39.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Prephenate dehydrogenase Short name=PDH EC=1.3.1.12 | ||||
| Gene names |
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| Organism | Staphylococcus epidermidis (strain ATCC 12228) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 176280 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 362 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Predicted. |
General annotation (Comments)
| Catalytic activity | Prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH. |
| Pathway | Amino-acid biosynthesis; L-tyrosine biosynthesis; L-tyrosine from prephenate: step 1/2. |
| Sequence similarities | Contains 1 ACT domain. Contains 1 prephenate/arogenate dehydrogenase domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis Tyrosine biosynthesis |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tyrosine biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | amino acid binding Inferred from electronic annotation. Source: InterPro prephenate dehydrogenase (NADP+) activityInferred from electronic annotation. Source: InterPro prephenate dehydrogenase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)." Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M. Mol. Microbiol. 49:1577-1593(2003) [PubMed: 12950922] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| AE015929 Genomic DNA. Translation: AAO04644.1. | |
| RefSeq | NP_764602.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1056563. |
| GenomeReviews | Gene locus SE_1047 in contig AE015929_GR. |
| KEGG | sep:SE1047. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8CPB5. |
| OMA | Q8CPB5. QRAIRWG. |
Enzyme and pathway databases | |
| BioCyc | SEPI176280:SE_1047-MON. |
Family and domain databases | |
| InterPro | IPR002912. ACT_bd. IPR003099. Prephen_DH. [Graphical view] |
| PANTHER | PTHR21363. Prephen_DH. 1 hit. |
| Pfam | PF01842. ACT. 1 hit. PF02153. PDH. 1 hit. [Graphical view] |
| PROSITE | PS51176. PDH_ADH. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TYRA_STAES | ||||||||
| Accession | Primary (citable) accession number: Q8CPB5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


