Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8CNI5

- ALD1_STAES

UniProt

Q8CNI5 - ALD1_STAES

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative aldehyde dehydrogenase SE_1720

Gene

SE_1720

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei245 – 2451By similarity
Active sitei279 – 2791By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi201 – 2077NADBy similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSEPI176280:GCDG-1770-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase SE_1720 (EC:1.2.1.3)
Gene namesi
Ordered Locus Names:SE_1720
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001411: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Putative aldehyde dehydrogenase SE_1720PRO_0000293561Add
BLAST

Proteomic databases

PRIDEiQ8CNI5.

Interactioni

Protein-protein interaction databases

STRINGi176280.SE1720.

Structurei

3D structure databases

ProteinModelPortaliQ8CNI5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
KOiK00128.
OMAiIRENNNE.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CNI5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRNFTKQYIN GEWVDSASGE TIDVINPATE EVMGKIAKGN EEDVNKAVDA
60 70 80 90 100
ADKVYLEFRH SSVEERRELL DKIVKEYQNR KNDLIEAITD ELGAPLSVSE
110 120 130 140 150
NVHYQMGLNH FTAARDALDS FQFEEQRGDD LVVKEAIGVA GLVTPWNFPT
160 170 180 190 200
NQTSLKLAAA FAAGSPVVLK PSEETPFAAI ILAEIFDKVG VPKGVFNLVN
210 220 230 240 250
GDGSGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK KVSLELGGKS
260 270 280 290 300
PYIVLDDVDV EEAANATTKK VVNNTGQVCT AGTRVLIPES IKEDYLTAVK
310 320 330 340 350
EAFSKVKVGQ PREEGTQVGP IISKKQFDQV QDYIDKGINE GAELFYGGPG
360 370 380 390 400
KPEGLDKGYF ARPTIFINVD NHMTIAQEEI FGPVMSVITY NNLDEAIEIA
410 420 430 440 450
NDTKYGLAGY VIGKDKDTLR HVARSIEAGT IEINEAGRKP DLPFGGYKES
460 470
GLGREWGDYG IEEFLEVKSI AGYFK
Length:475
Mass (Da):51,890
Last modified:March 1, 2003 - v1
Checksum:i905E024191EE75D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA. Translation: AAO05319.1.
RefSeqiNP_765275.1. NC_004461.1.

Genome annotation databases

EnsemblBacteriaiAAO05319; AAO05319; SE_1720.
GeneIDi1057384.
KEGGisep:SE1720.
PATRICi19609302. VBIStaEpi113981_1680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA. Translation: AAO05319.1 .
RefSeqi NP_765275.1. NC_004461.1.

3D structure databases

ProteinModelPortali Q8CNI5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 176280.SE1720.

Proteomic databases

PRIDEi Q8CNI5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO05319 ; AAO05319 ; SE_1720 .
GeneIDi 1057384.
KEGGi sep:SE1720.
PATRICi 19609302. VBIStaEpi113981_1680.

Phylogenomic databases

eggNOGi COG1012.
KOi K00128.
OMAi IRENNNE.
OrthoDBi EOG6BS8QW.

Enzyme and pathway databases

BioCyci SEPI176280:GCDG-1770-MONOMER.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
    Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
    Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12228.

Entry informationi

Entry nameiALD1_STAES
AccessioniPrimary (citable) accession number: Q8CNI5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3