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Q8CNI5

- ALD1_STAES

UniProt

Q8CNI5 - ALD1_STAES

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Protein
Putative aldehyde dehydrogenase SE_1720
Gene
SE_1720
Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei245 – 2451 By similarity
Active sitei279 – 2791 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi201 – 2077NAD By similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSEPI176280:GCDG-1770-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase SE_1720 (EC:1.2.1.3)
Gene namesi
Ordered Locus Names:SE_1720
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001411: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Putative aldehyde dehydrogenase SE_1720
PRO_0000293561Add
BLAST

Proteomic databases

PRIDEiQ8CNI5.

Interactioni

Protein-protein interaction databases

STRINGi176280.SE1720.

Structurei

3D structure databases

ProteinModelPortaliQ8CNI5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1012.
KOiK00128.
OMAiIRENNNE.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CNI5-1 [UniParc]FASTAAdd to Basket

« Hide

MRNFTKQYIN GEWVDSASGE TIDVINPATE EVMGKIAKGN EEDVNKAVDA    50
ADKVYLEFRH SSVEERRELL DKIVKEYQNR KNDLIEAITD ELGAPLSVSE 100
NVHYQMGLNH FTAARDALDS FQFEEQRGDD LVVKEAIGVA GLVTPWNFPT 150
NQTSLKLAAA FAAGSPVVLK PSEETPFAAI ILAEIFDKVG VPKGVFNLVN 200
GDGSGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK KVSLELGGKS 250
PYIVLDDVDV EEAANATTKK VVNNTGQVCT AGTRVLIPES IKEDYLTAVK 300
EAFSKVKVGQ PREEGTQVGP IISKKQFDQV QDYIDKGINE GAELFYGGPG 350
KPEGLDKGYF ARPTIFINVD NHMTIAQEEI FGPVMSVITY NNLDEAIEIA 400
NDTKYGLAGY VIGKDKDTLR HVARSIEAGT IEINEAGRKP DLPFGGYKES 450
GLGREWGDYG IEEFLEVKSI AGYFK 475
Length:475
Mass (Da):51,890
Last modified:March 1, 2003 - v1
Checksum:i905E024191EE75D1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015929 Genomic DNA. Translation: AAO05319.1.
RefSeqiNP_765275.1. NC_004461.1.

Genome annotation databases

EnsemblBacteriaiAAO05319; AAO05319; SE_1720.
GeneIDi1057384.
KEGGisep:SE1720.
PATRICi19609302. VBIStaEpi113981_1680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015929 Genomic DNA. Translation: AAO05319.1 .
RefSeqi NP_765275.1. NC_004461.1.

3D structure databases

ProteinModelPortali Q8CNI5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 176280.SE1720.

Proteomic databases

PRIDEi Q8CNI5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO05319 ; AAO05319 ; SE_1720 .
GeneIDi 1057384.
KEGGi sep:SE1720.
PATRICi 19609302. VBIStaEpi113981_1680.

Phylogenomic databases

eggNOGi COG1012.
KOi K00128.
OMAi IRENNNE.
OrthoDBi EOG6BS8QW.

Enzyme and pathway databases

BioCyci SEPI176280:GCDG-1770-MONOMER.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
    Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
    Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12228.

Entry informationi

Entry nameiALD1_STAES
AccessioniPrimary (citable) accession number: Q8CNI5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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