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Q8CNI5

- ALD1_STAES

UniProt

Q8CNI5 - ALD1_STAES

Protein

Putative aldehyde dehydrogenase SE_1720

Gene

SE_1720

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei245 – 2451By similarity
    Active sitei279 – 2791By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi201 – 2077NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciSEPI176280:GCDG-1770-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative aldehyde dehydrogenase SE_1720 (EC:1.2.1.3)
    Gene namesi
    Ordered Locus Names:SE_1720
    OrganismiStaphylococcus epidermidis (strain ATCC 12228)
    Taxonomic identifieri176280 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000001411: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475Putative aldehyde dehydrogenase SE_1720PRO_0000293561Add
    BLAST

    Proteomic databases

    PRIDEiQ8CNI5.

    Interactioni

    Protein-protein interaction databases

    STRINGi176280.SE1720.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CNI5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Phylogenomic databases

    eggNOGiCOG1012.
    KOiK00128.
    OMAiIRENNNE.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8CNI5-1 [UniParc]FASTAAdd to Basket

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    MRNFTKQYIN GEWVDSASGE TIDVINPATE EVMGKIAKGN EEDVNKAVDA    50
    ADKVYLEFRH SSVEERRELL DKIVKEYQNR KNDLIEAITD ELGAPLSVSE 100
    NVHYQMGLNH FTAARDALDS FQFEEQRGDD LVVKEAIGVA GLVTPWNFPT 150
    NQTSLKLAAA FAAGSPVVLK PSEETPFAAI ILAEIFDKVG VPKGVFNLVN 200
    GDGSGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK KVSLELGGKS 250
    PYIVLDDVDV EEAANATTKK VVNNTGQVCT AGTRVLIPES IKEDYLTAVK 300
    EAFSKVKVGQ PREEGTQVGP IISKKQFDQV QDYIDKGINE GAELFYGGPG 350
    KPEGLDKGYF ARPTIFINVD NHMTIAQEEI FGPVMSVITY NNLDEAIEIA 400
    NDTKYGLAGY VIGKDKDTLR HVARSIEAGT IEINEAGRKP DLPFGGYKES 450
    GLGREWGDYG IEEFLEVKSI AGYFK 475
    Length:475
    Mass (Da):51,890
    Last modified:March 1, 2003 - v1
    Checksum:i905E024191EE75D1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO05319.1.
    RefSeqiNP_765275.1. NC_004461.1.

    Genome annotation databases

    EnsemblBacteriaiAAO05319; AAO05319; SE_1720.
    GeneIDi1057384.
    KEGGisep:SE1720.
    PATRICi19609302. VBIStaEpi113981_1680.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO05319.1 .
    RefSeqi NP_765275.1. NC_004461.1.

    3D structure databases

    ProteinModelPortali Q8CNI5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 176280.SE1720.

    Proteomic databases

    PRIDEi Q8CNI5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO05319 ; AAO05319 ; SE_1720 .
    GeneIDi 1057384.
    KEGGi sep:SE1720.
    PATRICi 19609302. VBIStaEpi113981_1680.

    Phylogenomic databases

    eggNOGi COG1012.
    KOi K00128.
    OMAi IRENNNE.
    OrthoDBi EOG6BS8QW.

    Enzyme and pathway databases

    BioCyci SEPI176280:GCDG-1770-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
      Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
      Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 12228.

    Entry informationi

    Entry nameiALD1_STAES
    AccessioniPrimary (citable) accession number: Q8CNI5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3