Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8CMY5

- ALF1_STAES

UniProt

Q8CMY5 - ALF1_STAES

Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei175 – 1751Proton acceptorBy similarity
    Active sitei212 – 2121Schiff-base intermediate with dihydroxyacetone-PBy similarity

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    BioCyciSEPI176280:GCDG-2215-MONOMER.
    UniPathwayiUPA00109; UER00183.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
    Alternative name(s):
    Fructose-bisphosphate aldolase class I
    Short name:
    FBP aldolase
    Gene namesi
    Name:fda
    Ordered Locus Names:SE_2156
    OrganismiStaphylococcus epidermidis (strain ATCC 12228)
    Taxonomic identifieri176280 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000001411: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 296295Fructose-bisphosphate aldolase class 1PRO_0000216910Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi176280.SE2156.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CMY5.
    SMRiQ8CMY5. Positions 1-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG3588.
    KOiK01623.
    OMAiYTGDYLA.
    OrthoDBiEOG6M6JJT.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00729. FBP_aldolase_1.
    InterProiIPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view]
    PfamiPF00274. Glycolytic. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8CMY5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKEQLEKMT HGKGFIAALD QSGGSTPKAL KEYGVNEDQY SNEDEMFQLV    50
    HDMRTRVVTS PSFSPDKILG AILFEQTMDR EVEGKYTGDY LADKGVVPFL 100
    KVDKGLAEEK NGVQLMKPID DLDETLDRAN ERHIFGTKMR SNILELNEQG 150
    IKDVVEQQFE FAKKIIAKGL VPIIEPEVNI NAKDKSEIEK VLKAEIKKGL 200
    DSLNDDQLVM LKLTIPTEAN LYKDLADHPN VVRVVVLSGG YSRDEANKLL 250
    KDNDELIASF SRALASDLRA SQSQEEFDKA LGDAVDSIYD ASVNKN 296
    Length:296
    Mass (Da):33,052
    Last modified:January 23, 2007 - v3
    Checksum:i13258473A6438CE9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO05798.1.
    RefSeqiNP_765711.1. NC_004461.1.

    Genome annotation databases

    EnsemblBacteriaiAAO05798; AAO05798; SE_2156.
    GeneIDi1056263.
    KEGGisep:SE2156.
    PATRICi19610172. VBIStaEpi113981_2106.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015929 Genomic DNA. Translation: AAO05798.1 .
    RefSeqi NP_765711.1. NC_004461.1.

    3D structure databases

    ProteinModelPortali Q8CMY5.
    SMRi Q8CMY5. Positions 1-294.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 176280.SE2156.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO05798 ; AAO05798 ; SE_2156 .
    GeneIDi 1056263.
    KEGGi sep:SE2156.
    PATRICi 19610172. VBIStaEpi113981_2106.

    Phylogenomic databases

    eggNOGi COG3588.
    KOi K01623.
    OMAi YTGDYLA.
    OrthoDBi EOG6M6JJT.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00183 .
    BioCyci SEPI176280:GCDG-2215-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00729. FBP_aldolase_1.
    InterProi IPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view ]
    Pfami PF00274. Glycolytic. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
      Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
      Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 12228.

    Entry informationi

    Entry nameiALF1_STAES
    AccessioniPrimary (citable) accession number: Q8CMY5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 21, 2003
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 76 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3