Q8CMR6 (Q8CMR6_STAES) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cystathionine gamma-synthase EMBL AAO05965.1

Gene names

Ordered Locus Names:

SE_2323

Organism

Staphylococcus epidermidis (strain ATCC 12228) [Complete proteome] [HAMAP]

Taxonomic identifier

176280 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU004507
Sequence similarities	Belongs to the trans-sulfuration enzymes family. RuleBase RU004079

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU004507
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8CMR6 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 69322ACC3004BC1A	FASTA	381	41,862
	10 20 30 40 50 60 MNKKTQMIHG GHTTDNYTGA VTTPIYQTST YLQDDIGDLR QGYEYSRTAN PTRASLESVI 70 80 90 100 110 120 ANLEHGKHGF AFGSGMAAIS AVIMLLDKGD HLVLNSDVYG GTYRALTKVF TRFGIDVDFV 130 140 150 160 170 180 DTTKIENIEQ YIKPETKMLY VETPSNPLLR VTDIKASAKI AKKYDLISVV DNTFMTPYYQ 190 200 210 220 230 240 NPLDFGIDIV LHSATKYIGG HSDVVAGLVA TADDDLAERL GFISNSTGGV LGPQDSYLLI 250 260 270 280 290 300 RGIKTLGLRM EQINRNVEGI VQMLQKHPKV QQVFHPSIKE HMNYTIHQNQ ATGHTGVVSF 310 320 330 340 350 360 EVKDTEAAKQ VIHATNYFTL AESLGAVESL ISVPALMTHA SIPSDVRAKE GITDGLIRLS 370 380 IGIEDTEDLV NDLEQALNTL R

References

[1]

"Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)." Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M. Mol. Microbiol. 49:1577-1593(2003) [PubMed: 12950922] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015929 Genomic DNA. Translation: AAO05965.1.
RefSeq	NP_765878.1. NC_004461.1.
3D structure databases
HSSP	HSSP built from PDB template 1N8P based on UniProtKB P31373.
ProteinModelPortal	Q8CMR6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8CMR6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000039382; EBSTAP00000038015; EBSTAG00000039380.
GeneID	1057139.
GenomeReviews	Gene locus SE_2323 in contig AE015929_GR.
KEGG	sep:SE2323.
PATRIC	19610526. VBIStaEpi113981_2266.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0626.
GeneTree	EBGT00050000024435.
HOGENOM	HBG754729.
OMA	HEHYALA.
PhylomeDB	Q8CMR6.
ProtClustDB	CLSK886174.
Enzyme and pathway databases
BioCyc	SEPI176280:SE_2323-MONOMER.
Family and domain databases
InterPro	IPR000277. Cys/Met-Metab_PyrdxlP-dep_enz. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K01739.
PANTHER	PTHR11808. Cys_Met_Meta_PP. 1 hit.
Pfam	PF01053. Cys_Met_Meta_PP. 1 hit. [Graphical view]
PIRSF	PIRSF001434. CGS. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00868. CYS_MET_METAB_PP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8CMR6_STAES

Accession

Primary (citable) accession number: Q8CMR6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)