SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8CMP4

- SDRF_STAES

UniProt

Q8CMP4 - SDRF_STAES

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Serine-aspartate repeat-containing protein F
Gene
sdrF, SE_2395
Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Binds to type I collagen via alpha-2(I) or alpha-1(I) chains By similarity.

GO - Biological processi

  1. cell adhesion Source: InterPro
  2. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Virulence

Enzyme and pathway databases

BioCyciSEPI176280:GCDG-2468-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine-aspartate repeat-containing protein F
Gene namesi
Name:sdrF
Ordered Locus Names:SE_2395
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001411: Chromosome

Subcellular locationi

Secretedcell wall; Peptidoglycan-anchor Reviewed prediction

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 4545 Reviewed prediction
Add
BLAST
Chaini46 – 15971552Serine-aspartate repeat-containing protein F
PRO_0000304881Add
BLAST
Propeptidei1598 – 163336Removed by sortase Reviewed prediction
PRO_0000304882Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1597 – 15971Pentaglycyl murein peptidoglycan amidated threonine Reviewed prediction

Keywords - PTMi

Peptidoglycan-anchor

Interactioni

Protein-protein interaction databases

STRINGi176280.SE2395.

Structurei

3D structure databases

ProteinModelPortaliQ8CMP4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini679 – 797119CNA-B 1
Add
BLAST
Domaini798 – 907110CNA-B 2
Add
BLAST
Domaini908 – 1018111CNA-B 3
Add
BLAST
Domaini1019 – 1129111CNA-B 4
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni46 – 678633Ligand binding A region
Add
BLAST
Regioni679 – 1129451Type I collagen binding region By similarity
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi1594 – 15985LPXTG sorting signal Reviewed prediction

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1130 – 1587458Asp/Ser-rich
Add
BLAST

Domaini

Each CNA-B domain is able to independently mediate adherence to the substrate By similarity.

Sequence similaritiesi

Contains 4 CNA-B domains.

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG12793.
OMAiVTDITFQ.
OrthoDBiEOG6PKF9Z.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
2.60.40.1280. 1 hit.
InterProiIPR008966. Adhesion_dom.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR011252. Fibrogen-bd_dom1.
IPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR019931. LPXTG_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF05738. Cna_B. 4 hits.
PF00746. Gram_pos_anchor. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SUPFAMiSSF49401. SSF49401. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8CMP4-1 [UniParc]FASTAAdd to Basket

« Hide

MKKRRQGPIN KRVDFLSNKV NKYSIRKFTV GTASILVGAT LMFGAADNEA     50
KAAEDNQLES ASKEEQKGSR DNESSKLNQV DLDNGSHSSE KTTNVNNATE 100
VKKVEAPTTS DVSKPKANEA VVTNESTKPK TTEAPTVNEE SIAETPKTST 150
TQQDSTEKNN PSLKDNLNSS STTSKESKTD EHSTKQAQMS TNKSNLDTND 200
SPTQSEKTSS QANNDSTDNQ SAPSKQLDSK PSEQKVYKTK FNDEPTQDVE 250
HTTTKLKTPS ISTDSSVNDK QDYTRSAVAS LGVDSNETEA ITNAVRDNLD 300
LKAASREQIN EAIIAEALKK DFSNPDYGVD TPLALNTSQS KNSPHKSASP 350
RMNLMSLAAE PNSGKNVNDK VKITNPTLSL NKSNNHANNV IWPTSNEQFN 400
LKANYELDDS IKEGDTFTIK YGQYIRPGGL ELPAIKTQLR SKDGSIVANG 450
VYDKTTNTTT YTFTNYVDQY QNITGSFDLI ATPKRETAIK DNQNYPMEVT 500
IANEVVKKDF IVDYGNKKDN TTTAAVANVD NVNNKHNEVV YLNQNNQNPK 550
YAKYFSTVKN GKFIPGEVKV YEVTDTNAMV DSFNPDLNSS NVKDVTSQFT 600
PKVSADGTRV DINFARSMAN GKKYIVTQAV RPTGTGNVYT EYWLTRDGTT 650
NTNDFYRGTK STTVTYLNGS STAQGDNPTY SLGDYVWLDK NKNGVQDDDE 700
KGLAGVYVTL KDSNNRELQR VTTDQSGHYQ FDNLQNGTYT VEFAIPDNYT 750
PSPANNSTND AIDSDGERDG TRKVVVAKGT INNADNMTVD TGFYLTPKYN 800
VGDYVWEDTN KDGIQDDNEK GISNVKVTLK NKNGDTIGTT TTDSNGKYEF 850
TGLENGDYTI EFETPEGYTP TKQNSGSDEG KDSNGTKTTV TVKDADNKTI 900
DSGFYKPIYN LGDYVWEDTN KDGIQDDSEK GISGVKVTLK DKNGNAIGTT 950
TTDASGHYQF KGLENGSYTV EFETPSGYTP TKANSGQDIT VDSNGITTTG 1000
IINGADNLTI DSGFYKTPKY SVGDYVWEDT NKDGIQDDNE KGISGVKVTL 1050
KDEKGNIIST TTTDENGKYQ FDNLDSGNYI IHFEKPEGMT QTTANSGNDD 1100
EKDADGEDVR VTITDHDDFS IDNGYFDDDS DSDSDADSDS DSDSDSDADS 1150
DSDADSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDADSDS DADSDSDSDS 1200
DSDSDSDSDS DSDSDSDSDS DSDADSDSDA DSDSDADSDS DADSDSDSDS 1250
DSDADSDSDS DSDSDADSDS DSDSDSDADS DSDSDSDSDA DSDSDSDSDS 1300
DADSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDADSDS 1350
DSDSDSDADS DSDADSDSDS DSDSDSDSDS DADSDSDSDS DSDSDSDSDA 1400
DSDSDSDSDS DAESDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDADS 1450
DSDSDSDSDS DSDSDSDSDS DSDSDSDADS DSYSDSDSDS DSDSDSDSDS 1500
DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS 1550
DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDKNA KDKLPDTGAN 1600
EDHDSKGTLL GTLFAGLGAL LLGRRRKKDN KEK 1633
Length:1,633
Mass (Da):174,771
Last modified:March 1, 2003 - v1
Checksum:iDAA8537B8CD288BD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015929 Genomic DNA. Translation: AAO06038.1.
RefSeqiNP_765950.1. NC_004461.1.

Genome annotation databases

EnsemblBacteriaiAAO06038; AAO06038; SE_2395.
GeneIDi1057120.
KEGGisep:SE2395.
PATRICi19610664. VBIStaEpi113981_2335.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015929 Genomic DNA. Translation: AAO06038.1 .
RefSeqi NP_765950.1. NC_004461.1.

3D structure databases

ProteinModelPortali Q8CMP4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 176280.SE2395.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO06038 ; AAO06038 ; SE_2395 .
GeneIDi 1057120.
KEGGi sep:SE2395.
PATRICi 19610664. VBIStaEpi113981_2335.

Phylogenomic databases

eggNOGi NOG12793.
OMAi VTDITFQ.
OrthoDBi EOG6PKF9Z.

Enzyme and pathway databases

BioCyci SEPI176280:GCDG-2468-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 4 hits.
2.60.40.1280. 1 hit.
InterProi IPR008966. Adhesion_dom.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR011252. Fibrogen-bd_dom1.
IPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR019931. LPXTG_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
Pfami PF05738. Cna_B. 4 hits.
PF00746. Gram_pos_anchor. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SUPFAMi SSF49401. SSF49401. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)."
    Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.
    Mol. Microbiol. 49:1577-1593(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12228.

Entry informationi

Entry nameiSDRF_STAES
AccessioniPrimary (citable) accession number: Q8CMP4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi