Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Staphylococcus epidermidis (strain ATCC 12228)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei123FAD; via amide nitrogen and carbonyl oxygenUniRule annotation1
Binding sitei178FADUniRule annotation1
Binding sitei367FADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 16FADUniRule annotation6
Nucleotide bindingi270 – 284NADUniRule annotationAdd BLAST15

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processtRNA processing
LigandFAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciSEPI176280:G1G05-2489-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:SE_2416
OrganismiStaphylococcus epidermidis (strain ATCC 12228)
Taxonomic identifieri176280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000001411 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001171811 – 625tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGAdd BLAST625

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Protein-protein interaction databases

STRINGi176280.SE2416

Structurei

3D structure databases

ProteinModelPortaliQ8CMN6
SMRiQ8CMN6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RE5 Bacteria
COG0445 LUCA
KOiK03495
OMAiFRPGYAI

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00129 MnmG_GidA, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR026904 GidA-assoc_3
IPR004416 MnmG
IPR002218 MnmG-rel
IPR020595 MnmG-rel_CS
PANTHERiPTHR11806 PTHR11806, 1 hit
PTHR11806:SF0 PTHR11806:SF0, 1 hit
PfamiView protein in Pfam
PF01134 GIDA, 1 hit
PF13932 GIDA_assoc, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
TIGRFAMsiTIGR00136 gidA, 1 hit
PROSITEiView protein in PROSITE
PS01280 GIDA_1, 1 hit
PS01281 GIDA_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CMN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQEYDVVVI GAGHAGIEAG LASARRGAKT LMLTINLDNI AFMPCNPSVG
60 70 80 90 100
GPAKGIVVRE IDALGGQMAK TIDKTHIQMR MLNTGKGPAV RALRAQADKV
110 120 130 140 150
LYQQEMKRVL ENEDNLDIMQ GMVDELIIED NEVKGVRTNI GTEYRSKAVI
160 170 180 190 200
ITTGTFLRGE IILGNLKYSS GPNHQLPSVT LADNLRKLGF DIVRFKTGTP
210 220 230 240 250
PRVNARTIDY SKTEIQPGDD IGRAFSFETT EFILDQLPCW LTYTNGDTHQ
260 270 280 290 300
VIDDNLHLSA MYSGMIKGTG PRYCPSIEDK FVRFNDKPRH QLFLEPEGRN
310 320 330 340 350
TNEVYVQGLS TSLPEHVQRQ MLETIPGLEK ADMMRAGYAI EYDAIVPTQL
360 370 380 390 400
WPTLETKAIK NLYTAGQING TSGYEEAAGQ GIMAGINAAG NVLGTGEKIL
410 420 430 440 450
SRSDAYIGVL IDDLVTKGTN EPYRLLTSRA EYRLLLRHDN ADLRLTDMGY
460 470 480 490 500
ELGLISEERY ARFNEKRQQI KDEIQRLTDV RIKPNEHTQA IIEAKGGSRL
510 520 530 540 550
KDGILAIDLL RRPEMNYETI LEILEESHQL PEAVEEQVEI QTKYEGYINK
560 570 580 590 600
SLQQVEKVKR MEAKKIPEDL DYSKVDSLAS EAREKLAEVK PLNIAQASRI
610 620
SGVNPADISI LLVYLEQGKL QRVKQ
Length:625
Mass (Da):69,805
Last modified:March 1, 2003 - v1
Checksum:iBFA2A2B706AA13AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015929 Genomic DNA Translation: AAO06059.1
RefSeqiNP_765971.1, NC_004461.1
WP_001831818.1, NC_004461.1

Genome annotation databases

EnsemblBacteriaiAAO06059; AAO06059; SE_2416
GeneIDi1057212
KEGGisep:SE2416
PATRICifig|176280.10.peg.2355

Similar proteinsi

Entry informationi

Entry nameiMNMG_STAES
AccessioniPrimary (citable) accession number: Q8CMN6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health