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Q8CJR5

- PTA_STRCO

UniProt

Q8CJR5 - PTA_STRCO

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Protein

Phosphate acetyltransferase

Gene

pta

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in acetate metabolism.By similarity

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphate acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00340; UER00459.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:SCO5425
ORF Names:SC6A11.01c, SC8F4.29c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 697697Phosphate acetyltransferasePRO_0000405553Add
BLAST

Proteomic databases

PRIDEiQ8CJR5.

Interactioni

Subunit structurei

Homohexamer.By similarity

Protein-protein interaction databases

STRINGi100226.SCO5425.

Structurei

3D structure databases

ProteinModelPortaliQ8CJR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni366 – 697332Phosphate acetyltransferaseAdd
BLAST

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).By similarity

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.Curated
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

Phylogenomic databases

eggNOGiCOG0280.
HOGENOMiHOG000053797.
InParanoidiQ8CJR5.
KOiK13788.
OMAiATIRPAF.
OrthoDBiEOG6BKJ5W.
PhylomeDBiQ8CJR5.

Family and domain databases

Gene3Di3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamiPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsiTIGR00651. pta. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CJR5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRSVYVTGI DRGDGRQVVE LGVMELLTRQ VDRVGVFRPL VHDGPDRLFE
60 70 80 90 100
LLRARYRLSQ DPATVYGMDY QEASLLQAEQ GVDELVSALV DRFHLVARDY
110 120 130 140 150
DVVLVLGTDY ADTQFPDELS LNARLANEFG ASVLPVVGGR KQTADSVLAE
160 170 180 190 200
THNAFRAYDG LGCDVLAMVT NRVAREDRDE IAERLAHRLP VPCWVVPDEP
210 220 230 240 250
ALSAPTVSQI AHALGAEIVL GDDSGLARDA LDFVFGGAML PNLLAALTPG
260 270 280 290 300
CLVITPGDRA DLVIGTLAAH SAGTPPIAGV LLTLNEVPGE GILTLAARLA
310 320 330 340 350
PGTPVLSVTG TSFPTAERLF SLEGKLGAAT PRKAETALGL FERYVDTAEL
360 370 380 390 400
NKRVSAPSSD RVTPMMFEHK LLEQARSDLR RVVLPEGTEE RVLHAAEVLL
410 420 430 440 450
RRGVCELTLL GPVEQIRKKA ADLGIDLGGA ELIDPAASEL RDSFAEKYAA
460 470 480 490 500
LRAHKGVTVE LAYDVVSDVN YFGTLMVQEG FADGMVSGSV HSTAATIRPA
510 520 530 540 550
FEIIKTKPDA AIVSSVFFMC LADKVLVYGD CAVNPDPDAE QLADIATQSA
560 570 580 590 600
STAAQFGVEP RIAMLSYSTG TSGSGADVDK VREATELVRS RRPDLSVEGP
610 620 630 640 650
IQYDAAVEPS VAATKLPGSA VAGQASVLIF PDLNTGNNTY KAVQRSAGAI
660 670 680 690
AVGPVLQGLR KPVNDLSRGA LVQDIVNTVA ITAIQAQQSP TEKASAQ
Length:697
Mass (Da):74,047
Last modified:March 1, 2003 - v1
Checksum:iD52002198968B71E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939123 Genomic DNA. Translation: CAD55352.1.
RefSeqiNP_733663.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAD55352; CAD55352; CAD55352.
GeneIDi1100865.
KEGGisco:SCO5425.
PATRICi23740700. VBIStrCoe124346_5506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939123 Genomic DNA. Translation: CAD55352.1 .
RefSeqi NP_733663.1. NC_003888.3.

3D structure databases

ProteinModelPortali Q8CJR5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 100226.SCO5425.

Proteomic databases

PRIDEi Q8CJR5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD55352 ; CAD55352 ; CAD55352 .
GeneIDi 1100865.
KEGGi sco:SCO5425.
PATRICi 23740700. VBIStrCoe124346_5506.

Phylogenomic databases

eggNOGi COG0280.
HOGENOMi HOG000053797.
InParanoidi Q8CJR5.
KOi K13788.
OMAi ATIRPAF.
OrthoDBi EOG6BKJ5W.
PhylomeDBi Q8CJR5.

Enzyme and pathway databases

UniPathwayi UPA00340 ; UER00459 .

Family and domain databases

Gene3Di 3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view ]
Pfami PF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view ]
PIRSFi PIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsi TIGR00651. pta. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiPTA_STRCO
AccessioniPrimary (citable) accession number: Q8CJR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3