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Q8CJR5

- PTA_STRCO

UniProt

Q8CJR5 - PTA_STRCO

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Protein
Phosphate acetyltransferase
Gene
pta, SCO5425, SC6A11.01c, SC8F4.29c
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in acetate metabolism By similarity.

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphate acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00340; UER00459.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:SCO5425
ORF Names:SC6A11.01c, SC8F4.29c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 697697Phosphate acetyltransferase
PRO_0000405553Add
BLAST

Proteomic databases

PRIDEiQ8CJR5.

Interactioni

Subunit structurei

Homohexamer By similarity.

Protein-protein interaction databases

STRINGi100226.SCO5425.

Structurei

3D structure databases

ProteinModelPortaliQ8CJR5.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni366 – 697332Phosphate acetyltransferase
Add
BLAST

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Phylogenomic databases

eggNOGiCOG0280.
HOGENOMiHOG000053797.
KOiK13788.
OMAiATIRPAF.
OrthoDBiEOG6BKJ5W.
PhylomeDBiQ8CJR5.

Family and domain databases

Gene3Di3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamiPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsiTIGR00651. pta. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CJR5-1 [UniParc]FASTAAdd to Basket

« Hide

MTRSVYVTGI DRGDGRQVVE LGVMELLTRQ VDRVGVFRPL VHDGPDRLFE    50
LLRARYRLSQ DPATVYGMDY QEASLLQAEQ GVDELVSALV DRFHLVARDY 100
DVVLVLGTDY ADTQFPDELS LNARLANEFG ASVLPVVGGR KQTADSVLAE 150
THNAFRAYDG LGCDVLAMVT NRVAREDRDE IAERLAHRLP VPCWVVPDEP 200
ALSAPTVSQI AHALGAEIVL GDDSGLARDA LDFVFGGAML PNLLAALTPG 250
CLVITPGDRA DLVIGTLAAH SAGTPPIAGV LLTLNEVPGE GILTLAARLA 300
PGTPVLSVTG TSFPTAERLF SLEGKLGAAT PRKAETALGL FERYVDTAEL 350
NKRVSAPSSD RVTPMMFEHK LLEQARSDLR RVVLPEGTEE RVLHAAEVLL 400
RRGVCELTLL GPVEQIRKKA ADLGIDLGGA ELIDPAASEL RDSFAEKYAA 450
LRAHKGVTVE LAYDVVSDVN YFGTLMVQEG FADGMVSGSV HSTAATIRPA 500
FEIIKTKPDA AIVSSVFFMC LADKVLVYGD CAVNPDPDAE QLADIATQSA 550
STAAQFGVEP RIAMLSYSTG TSGSGADVDK VREATELVRS RRPDLSVEGP 600
IQYDAAVEPS VAATKLPGSA VAGQASVLIF PDLNTGNNTY KAVQRSAGAI 650
AVGPVLQGLR KPVNDLSRGA LVQDIVNTVA ITAIQAQQSP TEKASAQ 697
Length:697
Mass (Da):74,047
Last modified:March 1, 2003 - v1
Checksum:iD52002198968B71E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939123 Genomic DNA. Translation: CAD55352.1.
RefSeqiNP_733663.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAD55352; CAD55352; CAD55352.
GeneIDi1100865.
KEGGisco:SCO5425.
PATRICi23740700. VBIStrCoe124346_5506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939123 Genomic DNA. Translation: CAD55352.1 .
RefSeqi NP_733663.1. NC_003888.3.

3D structure databases

ProteinModelPortali Q8CJR5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 100226.SCO5425.

Proteomic databases

PRIDEi Q8CJR5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD55352 ; CAD55352 ; CAD55352 .
GeneIDi 1100865.
KEGGi sco:SCO5425.
PATRICi 23740700. VBIStrCoe124346_5506.

Phylogenomic databases

eggNOGi COG0280.
HOGENOMi HOG000053797.
KOi K13788.
OMAi ATIRPAF.
OrthoDBi EOG6BKJ5W.
PhylomeDBi Q8CJR5.

Enzyme and pathway databases

UniPathwayi UPA00340 ; UER00459 .

Family and domain databases

Gene3Di 3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view ]
Pfami PF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view ]
PIRSFi PIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsi TIGR00651. pta. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiPTA_STRCO
AccessioniPrimary (citable) accession number: Q8CJR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi