Q8CJR4 (Q8CJR4_STRCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphorylase RuleBase RU000587
EC=2.4.1.1 RuleBase RU000587

Gene names

Ordered Locus Names:

SCO5444

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	874 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587
Molecular function	Glycosyltransferase RuleBase RU000587 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8CJR4 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: A902B0BCD614CEDB	FASTA	874	96,330
	10 20 30 40 50 60 MRVKAIRRLT VRPVLPDPLR PLSDLARNLR WSWHPETRDL FHSVDPECWT ASGGDPVRLL 70 80 90 100 110 120 GTVRPARLAE LAEDRRFLRR LTAVAYDLDH YMTGDRWYQA QSGRLPAAVA YFSPEFGITA 130 140 150 160 170 180 ALPQYSGGLG ILAGDHLKAA SDLGVPLVGV GLLYRHGYFR QSLSRDGWQQ EHYPVLDPHE 190 200 210 220 230 240 LPLAPLKERD GTPAHVALAL PGGRELRARV WLAQVGRVPL LLLDSDVEEN DPGERGVTDR 250 260 270 280 290 300 LYGGGSEHRL LQEMLLGIGG VRAVRTYCRI TGHPAPEVFH TNEGHAGFLG LERIAELCDA 310 320 330 340 350 360 GSDFGSALEA VRAGTVFTTH TPVPAGIDRF DRELVARHFG PDAELPRIEV ERVLRLGMET 370 380 390 400 410 420 YPGGEPNLFN MAVMGLRLAQ RANGVSVLHG GVSRGMFAGL WPGFDADEVP ITSVTNGVHA 430 440 450 460 470 480 PTWVAPEVFR LGARQIGVQR AEDALAVGGS DRWDSVADIP DRDIWELRRT LRAQLVEEVR 490 500 510 520 530 540 ERLRASWRQR GAGTAELGWI DDALDPDVLT IGFARRVPSY KRLTLMLRDR ERLTELLLHP 550 560 570 580 590 600 ERPIQIVVAG KAHPADDGGK RLVQELVRFA DDARVRHRIV FLPDYGMAMA QKLYPGCDIW 610 620 630 640 650 660 LNNPLRPLEA CGTSGMKAAL NGCLNLSVLD GWWDEWYQPD FGWAIPTADG AGTDPDRRDA 670 680 690 700 710 720 IEADALYDLL EQRITPRFYE RGASGLPDRW LEMVRRTLSL LGPKVLAGRM VREYVERLYT 730 740 750 760 770 780 PAAEAHRAMD PDSARGLAEW KARVRAAWPG VSVDHVETSA ATASAELGTT LALRVRVKLG 790 800 810 820 830 840 DLAPEDVEVQ AVSGRVDSED RITDAARTSL KPVGGPDLEG RWAYEGPLAL DRTGPFGYTV 850 860 870 RVLPAHRLLA SGVETGLVAV PSGDLVEAAG LLMR

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939123 Genomic DNA. Translation: CAD55353.1.
RefSeq	NP_733664.1. NC_003888.3.
3D structure databases
ProteinModelPortal	Q8CJR4.
ModBase	Search...
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1100884.
GenomeReviews	Gene locus SCO5444 in contig AL645882_GR.
KEGG	sco:SCO5444.
NMPDR	fig|100226.1.peg.5396.
PATRIC	23740740. VBIStrCoe124346_5526.
Phylogenomic databases
HOGENOM	HBG302557.
OMA	LRWSWHP.
PhylomeDB	Q8CJR4.
ProtClustDB	CLSK915474.
Family and domain databases
InterPro	IPR011834. Agluc_phsphrylas. IPR000811. Glyco_trans_35. IPR024517. Glycogen_phosphorylase_DUF3417. [Graphical view]
KO	K00688.
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF11897. DUF3417. 1 hit. PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02094. More_P_ylases. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8CJR4_STRCO

Accession

Primary (citable) accession number: Q8CJR4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)