Q8CJR1 (Q8CJR1_STRCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Delta-1-pyrroline-5-carboxylate dehydrogenase EMBL CAD55356.1

Gene names

Ordered Locus Names:

SCO5520

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	546 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8CJR1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: C77FF21A82C58A1F	FASTA	546	59,363
	10 20 30 40 50 60 MDAVTQVPTP VNEPVHGYAP GSPERARLEA KLKELADNPI DLPCTIGGEK RMGGGERFDV 70 80 90 100 110 120 VQPHNHKSRL GTYANATQAD AQDAIDAALA AAPAWRAMSF DDRAAIILRA AELLSGPWRE 130 140 150 160 170 180 TIAASTMLGQ SKTAQQAEID SPCELIDFWR FNVHYARNIL AEQPPANSQG VWNRMDHRPL 190 200 210 220 230 240 EGFVYAITPF NFSAIAANLP TAPALMGNVV VWKPSPTQTH AAVLLMQLLE EAGLPKGVIN 250 260 270 280 290 300 LVTGDGIAVS EVALEHRDLA GIHFTGSTKT FQHLWKTVGN NIEKYRTYPR LVGETGGKDF 310 320 330 340 350 360 LVAHPSADRA VLKTALTRGA FEYQGQKCSA TSRAYIPASI WNDGFKEEFA AEVDYLTMGD 370 380 390 400 410 420 VTDLSNFIGA VIDERSFAKN KAAIDRAKED ETCTIVAGGS YDDSVGYFVR PTVVECTDPE 430 440 450 460 470 480 NEVFRTEYFG PFLAVHVYDD SADDAYDAML TQMESVSDYA LTGSVISNDR AAAAYTMEKL 490 500 510 520 530 540 RYAAGNFYIN DKSTGAVVGQ QPFGGGRASG TNDKAGAPQN LMRWTLTRAI KETLVAPTDY TYPHMG

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939124 Genomic DNA. Translation: CAD55356.1.
PIR	T29050. T35836.
RefSeq	NP_733667.1. NC_003888.3.
3D structure databases
ProteinModelPortal	Q8CJR1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1100960.
GenomeReviews	Gene locus SCO5520 in contig AL645882_GR.
KEGG	sco:SCO5520.
NMPDR	fig|100226.1.peg.5472.
PATRIC	23740902. VBIStrCoe124346_5607.
Phylogenomic databases
HOGENOM	HBG752218.
OMA	CELVDFW.
PhylomeDB	Q8CJR1.
ProtClustDB	CLSK871904.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8CJR1_STRCO

Accession

Primary (citable) accession number: Q8CJR1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)