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Q8CJ82 (Q8CJ82_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length168 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus By similarity SAAS SAAS008967.

Sequence similarities

Contains T-box DNA-binding domain. SAAS SAAS008967

Ontologies

Keywords
   Biological processTranscription
Transcription regulation SAAS SAAS018186
   Cellular componentNucleus SAAS SAAS008967
   LigandDNA-binding SAAS SAAS018186
Gene Ontology (GO)
   Biological_processatrioventricular bundle cell differentiation

Inferred from mutant phenotype PubMed 18467625. Source: MGI

blood vessel development

Inferred from mutant phenotype PubMed 12668638. Source: MGI

branching involved in mammary gland duct morphogenesis

Inferred from mutant phenotype PubMed 16222716. Source: MGI

cardiac muscle cell differentiation

Inferred from mutant phenotype PubMed 17234970. Source: MGI

cardiac muscle cell fate commitment

Inferred from mutant phenotype PubMed 18467625. Source: MGI

cell aging

Inferred from direct assay PubMed 11748239. Source: MGI

forelimb morphogenesis

Inferred from sequence orthology PubMed 9207801. Source: MGI

heart looping

Inferred from mutant phenotype PubMed 17460765PubMed 18723448. Source: MGI

heart morphogenesis

Inferred from mutant phenotype PubMed 17473172. Source: MGI

in utero embryonic development

Inferred from mutant phenotype PubMed 17473172. Source: MGI

limb morphogenesis

Inferred from mutant phenotype PubMed 12668638. Source: MGI

limbic system development

Inferred from mutant phenotype PubMed 17473172. Source: MGI

mammary gland development

Inferred from mutant phenotype PubMed 12668638PubMed 16222716PubMed 17473172. Source: MGI

mammary placode formation

Inferred from direct assay PubMed 17071745. Source: MGI

negative regulation of epithelial cell differentiation

Inferred from mutant phenotype PubMed 18356246. Source: MGI

negative regulation of transcription, DNA-templated

Inferred from direct assay PubMed 11748239. Source: MGI

organ morphogenesis

Inferred from sequence orthology PubMed 9207801. Source: MGI

outflow tract morphogenesis

Inferred from mutant phenotype PubMed 18723448. Source: MGI

palate development

Inferred from genetic interaction PubMed 19769959. Source: MGI

positive regulation of stem cell proliferation

Inferred from mutant phenotype PubMed 18356246. Source: MGI

positive regulation of transcription, DNA-templated

Inferred from mutant phenotype PubMed 17473172. Source: MGI

regulation of cell proliferation

Inferred from mutant phenotype PubMed 17460765. Source: MGI

sinoatrial node cell development

Inferred from mutant phenotype PubMed 19096026. Source: MGI

specification of organ position

Inferred from direct assay PubMed 17071745. Source: MGI

stem cell maintenance

Inferred from mutant phenotype PubMed 18356246. Source: MGI

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

ventricular septum morphogenesis

Inferred from mutant phenotype PubMed 18467625. Source: MGI

   Cellular_componentnucleus

Inferred from direct assay PubMed 18534921PubMed 18723448PubMed 19765559. Source: MGI

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

sequence-specific DNA binding transcription factor activity

Inferred from direct assay PubMed 17473172. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAN37692.1
Non-terminal residue1681 EMBL AAN37692.1

Sequences

Sequence LengthMass (Da)Tools
Q8CJ82 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 914EA2F26358E5BC

FASTA16819,634
        10         20         30         40         50         60 
EMVITKSGRR MFPPFKVRCS GLDKKAKYIL LMDIIAADDC RYKFHNSRWM VAGKADPEMP 

        70         80         90        100        110        120 
KRMYIHPDSP ATGEQWMSKV VTFHKLKLTN NISDKHGFTI LNSMHKYQPR FHIVRANDIL 

       130        140        150        160 
KLPYSTFRTY LFPETEFIAV TAYQNDKITQ LKIDNNPFAK GFRDIGHC 

« Hide

References

[1]"Regulation of Tbx3 expression by anteroposterior signalling in vertebrate limb development."
Tumpel S., Sanz-Ezquerro J.J., Isaac A., Eblaghie M.C., Dobson J., Tickle C.
Dev. Biol. 250:251-262(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CD-1 EMBL AAN37692.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF429310 mRNA. Translation: AAN37692.1.
UniGeneMm.219139.

3D structure databases

ProteinModelPortalQ8CJ82.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000018748.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:98495. Tbx3.

Phylogenomic databases

HOVERGENHBG004599.

Gene expression databases

GenevestigatorQ8CJ82.

Family and domain databases

Gene3D2.60.40.820. 1 hit.
InterProIPR008967. p53-like_TF_DNA-bd.
IPR002070. TF_Brachyury.
IPR001699. TF_T-box.
IPR018186. TF_T-box_CS.
[Graphical view]
PANTHERPTHR11267. PTHR11267. 1 hit.
PfamPF00907. T-box. 1 hit.
[Graphical view]
PRINTSPR00938. BRACHYURY.
PR00937. TBOX.
SMARTSM00425. TBOX. 1 hit.
[Graphical view]
SUPFAMSSF49417. SSF49417. 1 hit.
PROSITEPS01264. TBOX_2. 1 hit.
PS50252. TBOX_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ8CJ82_MOUSE
AccessionPrimary (citable) accession number: Q8CJ82
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)