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Protein

CKLF-like MARVEL transmembrane domain-containing protein 4

Gene

Cmtm4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Cytokine

Keywords - Biological processi

Chemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
CKLF-like MARVEL transmembrane domain-containing protein 4
Alternative name(s):
Chemokine-like factor superfamily member 4
Gene namesi
Name:Cmtm4
Synonyms:Cklfsf4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2142888. Cmtm4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei59 – 7921HelicalSequence analysisAdd
BLAST
Transmembranei85 – 10521HelicalSequence analysisAdd
BLAST
Transmembranei123 – 14321HelicalSequence analysisAdd
BLAST
Transmembranei151 – 17121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208CKLF-like MARVEL transmembrane domain-containing protein 4PRO_0000186104Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei194 – 1941PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8CJ61.
PaxDbiQ8CJ61.
PeptideAtlasiQ8CJ61.
PRIDEiQ8CJ61.

PTM databases

iPTMnetiQ8CJ61.
PhosphoSiteiQ8CJ61.

Expressioni

Gene expression databases

BgeeiENSMUSG00000096188.
GenevisibleiQ8CJ61. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137332.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 176128MARVELPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the chemokine-like factor family.Curated
Contains 1 MARVEL domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4788. Eukaryota.
ENOG4111IAF. LUCA.
GeneTreeiENSGT00530000063578.
HOGENOMiHOG000261609.
HOVERGENiHBG050980.
InParanoidiQ8CJ61.
OMAiAVQKWRV.
OrthoDBiEOG091G0KPO.
PhylomeDBiQ8CJ61.
TreeFamiTF317387.

Family and domain databases

InterProiIPR008253. Marvel.
[Graphical view]
PfamiPF01284. MARVEL. 1 hit.
[Graphical view]
PROSITEiPS51225. MARVEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CJ61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGGEELDGF EGEASSTSMI SGASSPYQPT TEPVSQRRGL AGLRCDPDYL
60 70 80 90 100
RGALGRLKVA QVILALIAFI CIETIMECSP CEGLYFFEFV SCSAFVVTGV
110 120 130 140 150
LLILFSLNLH MRIPQINWNL TDLVNTGLST FFFFIASIVL AALNHKTGAE
160 170 180 190 200
IAAVIFGFLA TAAYAVSTFL AMQKWRVSVR QQSTNDYIRA RTESRDVDSR

PEIQRLDT
Length:208
Mass (Da):22,921
Last modified:March 1, 2003 - v1
Checksum:iCDC27CDE02EDA06E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF479815 mRNA. Translation: AAN73437.1.
BC028852 mRNA. Translation: AAH28852.2.
CCDSiCCDS22578.1.
RefSeqiNP_705810.2. NM_153582.5.
UniGeneiMm.29658.

Genome annotation databases

EnsembliENSMUST00000179802; ENSMUSP00000137332; ENSMUSG00000096188.
GeneIDi97487.
KEGGimmu:97487.
UCSCiuc009nan.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF479815 mRNA. Translation: AAN73437.1.
BC028852 mRNA. Translation: AAH28852.2.
CCDSiCCDS22578.1.
RefSeqiNP_705810.2. NM_153582.5.
UniGeneiMm.29658.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137332.

PTM databases

iPTMnetiQ8CJ61.
PhosphoSiteiQ8CJ61.

Proteomic databases

MaxQBiQ8CJ61.
PaxDbiQ8CJ61.
PeptideAtlasiQ8CJ61.
PRIDEiQ8CJ61.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000179802; ENSMUSP00000137332; ENSMUSG00000096188.
GeneIDi97487.
KEGGimmu:97487.
UCSCiuc009nan.2. mouse.

Organism-specific databases

CTDi146223.
MGIiMGI:2142888. Cmtm4.

Phylogenomic databases

eggNOGiKOG4788. Eukaryota.
ENOG4111IAF. LUCA.
GeneTreeiENSGT00530000063578.
HOGENOMiHOG000261609.
HOVERGENiHBG050980.
InParanoidiQ8CJ61.
OMAiAVQKWRV.
OrthoDBiEOG091G0KPO.
PhylomeDBiQ8CJ61.
TreeFamiTF317387.

Miscellaneous databases

PROiQ8CJ61.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000096188.
GenevisibleiQ8CJ61. MM.

Family and domain databases

InterProiIPR008253. Marvel.
[Graphical view]
PfamiPF01284. MARVEL. 1 hit.
[Graphical view]
PROSITEiPS51225. MARVEL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCKLF4_MOUSE
AccessioniPrimary (citable) accession number: Q8CJ61
Secondary accession number(s): Q8K143
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.