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Protein

Adhesion G-protein coupled receptor G2

Gene

Adgrg2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within epididymis.1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Protein family/group databases

MEROPSiP02.007.

Names & Taxonomyi

Protein namesi
Recommended name:
Adhesion G-protein coupled receptor G2
Alternative name(s):
G-protein coupled receptor 64
Mouse epididymis-specific protein 6
Short name:
Me6
Gene namesi
Name:Adgrg2Imported
Synonyms:Gpr64, Me6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2446854. Adgrg2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini38 – 619582ExtracellularCuratedAdd
BLAST
Transmembranei620 – 64021Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini641 – 65919CytoplasmicCuratedAdd
BLAST
Transmembranei660 – 68021Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini681 – 6833ExtracellularCurated
Transmembranei684 – 70421Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini705 – 72925CytoplasmicCuratedAdd
BLAST
Transmembranei730 – 75021Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini751 – 78131ExtracellularCuratedAdd
BLAST
Transmembranei782 – 80221Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini803 – 82624CytoplasmicCuratedAdd
BLAST
Transmembranei827 – 84721Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini848 – 8492ExtracellularCurated
Transmembranei850 – 87021Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini871 – 1009139CytoplasmicCuratedAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Mutant male are infertile. Targeted disruption leads to sperm stasis and duct obstruction, resulting from dysregulation of fluid reabsorption.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3737Sequence analysisAdd
BLAST
Chaini38 – 1009972Adhesion G-protein coupled receptor G2PRO_0000012887Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi43 – 431N-linked (GlcNAc...)Sequence analysis
Glycosylationi77 – 771N-linked (GlcNAc...)Sequence analysis
Glycosylationi91 – 911N-linked (GlcNAc...)Sequence analysis
Glycosylationi103 – 1031N-linked (GlcNAc...)Sequence analysis
Glycosylationi109 – 1091N-linked (GlcNAc...)Sequence analysis
Glycosylationi127 – 1271N-linked (GlcNAc...)Sequence analysis
Glycosylationi136 – 1361N-linked (GlcNAc...)Sequence analysis
Glycosylationi154 – 1541N-linked (GlcNAc...)Sequence analysis
Glycosylationi178 – 1781N-linked (GlcNAc...)Sequence analysis
Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence analysis
Glycosylationi362 – 3621N-linked (GlcNAc...)Sequence analysis
Glycosylationi427 – 4271N-linked (GlcNAc...)Sequence analysis
Glycosylationi448 – 4481N-linked (GlcNAc...)Sequence analysis
Glycosylationi453 – 4531N-linked (GlcNAc...)Sequence analysis
Glycosylationi520 – 5201N-linked (GlcNAc...)Sequence analysis
Glycosylationi534 – 5341N-linked (GlcNAc...)Sequence analysis
Glycosylationi539 – 5391N-linked (GlcNAc...)Sequence analysis
Glycosylationi543 – 5431N-linked (GlcNAc...)Sequence analysis
Glycosylationi589 – 5891N-linked (GlcNAc...)Sequence analysis
Glycosylationi849 – 8491N-linked (GlcNAc...)Sequence analysis
Modified residuei1002 – 10021PhosphoserineCombined sources

Post-translational modificationi

Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.Curated
Highly glycosylated.1 Publication

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ8CJ12.
PaxDbiQ8CJ12.
PRIDEiQ8CJ12.

PTM databases

PhosphoSiteiQ8CJ12.

Expressioni

Tissue specificityi

Epididymis-specific expression (at protein level). Associated with apical membranes of efferent ductule and proximal epididymal duct epithelia. Mainly expressed in the nonciliated principal cells of the proximal excurrent ducts.2 Publications

Gene expression databases

BgeeiQ8CJ12.
CleanExiMM_GPR64.
ExpressionAtlasiQ8CJ12. baseline and differential.
GenevisibleiQ8CJ12. MM.

Interactioni

Subunit structurei

Heterodimer of 2 chains generated by proteolytic processing; the large extracellular N-terminal fragment and the membrane-bound C-terminal fragment predominantly remain associated and non-covalently linked.Curated

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108019.

Structurei

3D structure databases

ProteinModelPortaliQ8CJ12.
SMRiQ8CJ12. Positions 623-872.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini559 – 61052GPSPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi248 – 2514Poly-Ser
Compositional biasi664 – 6696Poly-Leu
Compositional biasi808 – 8114Poly-Lys
Compositional biasi917 – 9226Poly-Ser

Sequence similaritiesi

Contains 1 GPS domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4193. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00830000128227.
HOVERGENiHBG051817.
InParanoidiQ8CJ12.
KOiK08451.
OMAiFIFYCVA.
OrthoDBiEOG7ZGX28.
PhylomeDBiQ8CJ12.
TreeFamiTF321769.

Family and domain databases

InterProiIPR017981. GPCR_2-like.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]

Sequences (5)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 5 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8CJ12-1) [UniParc]FASTAAdd to basket

Also known as: Long

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLFSGGQYSP VGRPEEVLLI YKIFLVIICF HVILVTSLKE NGNSSLLSPS
60 70 80 90 100
AESSLVSLIP YSNGTPDAAS EVLSTLNKTE KSKITIVKTF NASGVKSQRN
110 120 130 140 150
ICNLSSLCND SVFFRGEIVF QHDEDHNVTQ NQDTANGTFA GVLSLSELKR
160 170 180 190 200
SELNKTLQTL SETYFIVCAT AEAQSTVNCT FTVKLNETMN VCAMMVTFQT
210 220 230 240 250
VQIRPMEQCC CSPRTPCPSS PEELEKLQCE LQDPIVCLAD QPHGPPLSSS
260 270 280 290 300
SKPVVPQATI ISHVASDFSL AEPLDHALMT PSTPSLTQES NLPSPQPTIP
310 320 330 340 350
LASSPATDLP VQSVVVSSLP QTDLSHTLSP VQSSIPSPTT PAPSVPTELV
360 370 380 390 400
TISTPPGETV VNTSTVSDLE AQVSQMEKAL SLGSLEPNLA GEMVNRVSKL
410 420 430 440 450
LHSPPALLAP LAQRLLKVVD AIGLQLNFSS TTISLTSPSL ALAVIRVNAS
460 470 480 490 500
NFNTTTFAAQ DPTNLQVSLE TPPPENSIGA ITLPSSLMNN LPANDVELAS
510 520 530 540 550
RIQFNFFETP ALFQDPSLEN LTLISYVISS SVTNMTIKNL TRNVTVALKH
560 570 580 590 600
INPSPDDLTV KCVFWDLGRN GGKGGWSSDG CSVKDKRMNE TICTCSHLTS
610 620 630 640 650
FGILLDLSRT SLPPSQMMAL TFITYIGCGL SSIFLSVTLV TYIAFEKIRR
660 670 680 690 700
DYPSKILIQL CAALLLLNLI FLLDSWIALY NTRGFCIAVA VFLHYFLLVS
710 720 730 740 750
FTWMGLEAFH MYLALVKVFN TYIRKYILKF CIVGWGIPAV VVSIVLTISP
760 770 780 790 800
DNYGIGSYGK FPNGTPDDFC WINSNVVFYI TVVGYFCVIF LLNVSMFIVV
810 820 830 840 850
LVQLCRIKKK KQLGAQRKTS IQDLRSIAGL TFLLGITWGF AFFAWGPVNV
860 870 880 890 900
TFMYLFAIFN TLQGFFIFIF YCAAKENVRK QWRRYLCCGK LRLAENSDWS
910 920 930 940 950
KTATNGLKKQ TVNQGVSSSS NSLQSSCNST NSTTLLVNSD CSVHASGNGN
960 970 980 990 1000
ASTERNGVSF SVQNGDVCLH DLTGKQHMFS DKEDSCNGKS RIALRRTSKR

GSLHFIEQM
Length:1,009
Mass (Da):110,200
Last modified:March 1, 2003 - v1
Checksum:iA53C67C5527A5B6C
GO
Isoform 2 (identifier: Q8CJ12-2) [UniParc]FASTAAdd to basket

Also known as: d2

The sequence of this isoform differs from the canonical sequence as follows:
     64-66: Missing.

Show »
Length:1,006
Mass (Da):109,945
Checksum:i84EB92A305DAAF64
GO
Isoform 3 (identifier: Q8CJ12-3) [UniParc]FASTAAdd to basket

Also known as: d1

The sequence of this isoform differs from the canonical sequence as follows:
     80-93: Missing.

Show »
Length:995
Mass (Da):108,652
Checksum:i0B11972D6B6DD226
GO
Isoform 4 (identifier: Q8CJ12-4) [UniParc]FASTAAdd to basket

Also known as: d3

The sequence of this isoform differs from the canonical sequence as follows:
     51-66: Missing.

Show »
Length:993
Mass (Da):108,583
Checksum:i4E63FEF1D355E6EF
GO
Isoform 5 (identifier: Q8CJ12-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     40-66: Missing.

Show »
Length:982
Mass (Da):107,497
Checksum:iA73D80E41A0E08B3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti781 – 7811T → K in BAC32902 (PubMed:16141072).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei40 – 6627Missing in isoform 5. 1 PublicationVSP_009806Add
BLAST
Alternative sequencei51 – 6616Missing in isoform 4. 1 PublicationVSP_009807Add
BLAST
Alternative sequencei64 – 663Missing in isoform 2. 1 PublicationVSP_009808
Alternative sequencei80 – 9314Missing in isoform 3. 1 PublicationVSP_009809Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF538952 mRNA. Translation: AAN33054.1.
AF538955 mRNA. Translation: AAN33057.1.
AF538956 mRNA. Translation: AAN33058.1.
AF538957 mRNA. Translation: AAN33059.1.
AK046871 mRNA. Translation: BAC32902.1.
AL731801 Genomic DNA. Translation: CAM16675.1.
AL731801 Genomic DNA. Translation: CAM16676.1.
AL731801 Genomic DNA. Translation: CAM16677.1.
AL731801 Genomic DNA. Translation: CAM16680.1.
CCDSiCCDS41196.1. [Q8CJ12-1]
CCDS41197.1. [Q8CJ12-3]
CCDS41199.1. [Q8CJ12-5]
CCDS72459.1. [Q8CJ12-2]
CCDS81192.1. [Q8CJ12-4]
RefSeqiNP_001073317.1. NM_001079848.2. [Q8CJ12-5]
NP_001073326.1. NM_001079857.2. [Q8CJ12-3]
NP_001277374.1. NM_001290445.1. [Q8CJ12-4]
NP_001277375.1. NM_001290446.1. [Q8CJ12-2]
NP_848827.1. NM_178712.4. [Q8CJ12-1]
UniGeneiMm.213016.

Genome annotation databases

EnsembliENSMUST00000112400; ENSMUSP00000108019; ENSMUSG00000031298. [Q8CJ12-1]
ENSMUST00000112402; ENSMUSP00000108021; ENSMUSG00000031298. [Q8CJ12-3]
ENSMUST00000112404; ENSMUSP00000108023; ENSMUSG00000031298. [Q8CJ12-5]
ENSMUST00000112405; ENSMUSP00000108024; ENSMUSG00000031298. [Q8CJ12-4]
ENSMUST00000112408; ENSMUSP00000108027; ENSMUSG00000031298. [Q8CJ12-2]
GeneIDi237175.
KEGGimmu:237175.
UCSCiuc009utd.2. mouse. [Q8CJ12-1]
uc009ute.2. mouse. [Q8CJ12-3]
uc009utg.2. mouse. [Q8CJ12-5]
uc009uth.2. mouse. [Q8CJ12-2]
uc009uti.2. mouse. [Q8CJ12-4]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF538952 mRNA. Translation: AAN33054.1.
AF538955 mRNA. Translation: AAN33057.1.
AF538956 mRNA. Translation: AAN33058.1.
AF538957 mRNA. Translation: AAN33059.1.
AK046871 mRNA. Translation: BAC32902.1.
AL731801 Genomic DNA. Translation: CAM16675.1.
AL731801 Genomic DNA. Translation: CAM16676.1.
AL731801 Genomic DNA. Translation: CAM16677.1.
AL731801 Genomic DNA. Translation: CAM16680.1.
CCDSiCCDS41196.1. [Q8CJ12-1]
CCDS41197.1. [Q8CJ12-3]
CCDS41199.1. [Q8CJ12-5]
CCDS72459.1. [Q8CJ12-2]
CCDS81192.1. [Q8CJ12-4]
RefSeqiNP_001073317.1. NM_001079848.2. [Q8CJ12-5]
NP_001073326.1. NM_001079857.2. [Q8CJ12-3]
NP_001277374.1. NM_001290445.1. [Q8CJ12-4]
NP_001277375.1. NM_001290446.1. [Q8CJ12-2]
NP_848827.1. NM_178712.4. [Q8CJ12-1]
UniGeneiMm.213016.

3D structure databases

ProteinModelPortaliQ8CJ12.
SMRiQ8CJ12. Positions 623-872.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108019.

Protein family/group databases

MEROPSiP02.007.
GPCRDBiSearch...

PTM databases

PhosphoSiteiQ8CJ12.

Proteomic databases

MaxQBiQ8CJ12.
PaxDbiQ8CJ12.
PRIDEiQ8CJ12.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000112400; ENSMUSP00000108019; ENSMUSG00000031298. [Q8CJ12-1]
ENSMUST00000112402; ENSMUSP00000108021; ENSMUSG00000031298. [Q8CJ12-3]
ENSMUST00000112404; ENSMUSP00000108023; ENSMUSG00000031298. [Q8CJ12-5]
ENSMUST00000112405; ENSMUSP00000108024; ENSMUSG00000031298. [Q8CJ12-4]
ENSMUST00000112408; ENSMUSP00000108027; ENSMUSG00000031298. [Q8CJ12-2]
GeneIDi237175.
KEGGimmu:237175.
UCSCiuc009utd.2. mouse. [Q8CJ12-1]
uc009ute.2. mouse. [Q8CJ12-3]
uc009utg.2. mouse. [Q8CJ12-5]
uc009uth.2. mouse. [Q8CJ12-2]
uc009uti.2. mouse. [Q8CJ12-4]

Organism-specific databases

CTDi10149.
MGIiMGI:2446854. Adgrg2.

Phylogenomic databases

eggNOGiKOG4193. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00830000128227.
HOVERGENiHBG051817.
InParanoidiQ8CJ12.
KOiK08451.
OMAiFIFYCVA.
OrthoDBiEOG7ZGX28.
PhylomeDBiQ8CJ12.
TreeFamiTF321769.

Miscellaneous databases

NextBioi383232.
PROiQ8CJ12.
SOURCEiSearch...

Gene expression databases

BgeeiQ8CJ12.
CleanExiMM_GPR64.
ExpressionAtlasiQ8CJ12. baseline and differential.
GenevisibleiQ8CJ12. MM.

Family and domain databases

InterProiIPR017981. GPCR_2-like.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia."
    Obermann H., Samalecos A., Osterhoff C., Schroeder B., Heller R., Kirchhoff C.
    Mol. Reprod. Dev. 64:13-26(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 4 AND 5), TISSUE SPECIFICITY, SUBUNIT, GLYCOSYLATION, SUBCELLULAR LOCATION.
    Strain: NMRI.
    Tissue: Epididymis.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Strain: C57BL/6J.
    Tissue: Medulla oblongata.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "Targeted deletion of the epididymal receptor HE6 results in fluid dysregulation and male infertility."
    Davies B., Baumann C., Kirchhoff C., Ivell R., Nubbemeyer R., Habenicht U.F., Theuring F., Gottwald U.
    Mol. Cell. Biol. 24:8642-8648(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE, FUNCTION.
  5. "HE6/GPR64 adhesion receptor co-localizes with apical and subapical F-actin scaffold in male excurrent duct epithelia."
    Kirchhoff C., Osterhoff C., Samalecos A.
    Reproduction 136:235-245(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1002, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Lung.

Entry informationi

Entry nameiAGRG2_MOUSE
AccessioniPrimary (citable) accession number: Q8CJ12
Secondary accession number(s): A2AHP8
, A2AHP9, A2AHQ0, A2AHQ3, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 1, 2003
Last modified: May 11, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.