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Q8CIE0

- SPA11_MOUSE

UniProt

Q8CIE0 - SPA11_MOUSE

Protein

Serpin A11

Gene

Serpina11

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. serine-type endopeptidase inhibitor activity Source: RefGenome

    GO - Biological processi

    1. negative regulation of endopeptidase activity Source: RefGenome
    2. regulation of proteolysis Source: RefGenome

    Keywords - Molecular functioni

    Protease inhibitor, Serine protease inhibitor

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serpin A11
    Gene namesi
    Name:Serpina11
    Synonyms:Gm895
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    Organism-specific databases

    MGIiMGI:2685741. Serpina11.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular space Source: InterPro

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2121Sequence AnalysisAdd
    BLAST
    Chaini22 – 424403Serpin A11PRO_0000041974Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi108 – 1081N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi171 – 1711N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi352 – 3521N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi387 – 3871N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ8CIE0.
    PRIDEiQ8CIE0.

    PTM databases

    PhosphoSiteiQ8CIE0.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8CIE0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CIE0.
    SMRiQ8CIE0. Positions 57-421.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the serpin family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG4826.
    HOGENOMiHOG000238521.
    HOVERGENiHBG005957.
    InParanoidiQ8CIE0.
    PhylomeDBiQ8CIE0.

    Family and domain databases

    InterProiIPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view]
    PANTHERiPTHR11461. PTHR11461. 1 hit.
    PfamiPF00079. Serpin. 1 hit.
    [Graphical view]
    SMARTiSM00093. SERPIN. 1 hit.
    [Graphical view]
    SUPFAMiSSF56574. SSF56574. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8CIE0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGPVWLWLWL LVAEVLLPVH CQPFSAHGDK SLGASQPASH QSLEPAPAYH    50
    KVTPTITNFA LRLYKQLAEE VAGNILFSPV SLSSSLALLS LGAHADTQTQ 100
    ILESLGFNLT ETPAADVHRG FQSLLHTLDL PSPKLELKLG HSLFLDRQLK 150
    PQQRFLDSAK ELYGALAFSA NFTEAAATGQ QINDLVRKQT YGQVVGCLPE 200
    FSHDTLMVLL NYIFFKAKWK HPFDRYQTRK QESFSLDQRT PLRIPMMRQK 250
    EMHRFLYDQE ASCTVLQIEY SGTALLLLVL PDPGKMQQVE AALQPETLRR 300
    WGQRFLPSLL DLHLPRFSIS ATYNLEEILP LIGLGNLFDM EADLSGIMGQ 350
    LNKTVSRVSH KAIVDMNEKG TEAAAASGLL SQPPALNMTS APQAHYNRPF 400
    LLLLWEVTTQ SLLFLGKVVN PAAG 424
    Length:424
    Mass (Da):47,188
    Last modified:March 1, 2003 - v1
    Checksum:iD176AAF8D5A06D34
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC024087 mRNA. Translation: AAH24087.1.
    BC096585 mRNA. Translation: AAH96585.1.
    RefSeqiNP_955018.2. NM_199314.2.
    UniGeneiMm.201338.

    Genome annotation databases

    GeneIDi380780.
    KEGGimmu:380780.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC024087 mRNA. Translation: AAH24087.1 .
    BC096585 mRNA. Translation: AAH96585.1 .
    RefSeqi NP_955018.2. NM_199314.2.
    UniGenei Mm.201338.

    3D structure databases

    ProteinModelPortali Q8CIE0.
    SMRi Q8CIE0. Positions 57-421.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q8CIE0.

    Proteomic databases

    PaxDbi Q8CIE0.
    PRIDEi Q8CIE0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 380780.
    KEGGi mmu:380780.

    Organism-specific databases

    CTDi 256394.
    MGIi MGI:2685741. Serpina11.

    Phylogenomic databases

    eggNOGi COG4826.
    HOGENOMi HOG000238521.
    HOVERGENi HBG005957.
    InParanoidi Q8CIE0.
    PhylomeDBi Q8CIE0.

    Miscellaneous databases

    NextBioi 401226.
    PROi Q8CIE0.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8CIE0.

    Family and domain databases

    InterProi IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view ]
    PANTHERi PTHR11461. PTHR11461. 1 hit.
    Pfami PF00079. Serpin. 1 hit.
    [Graphical view ]
    SMARTi SM00093. SERPIN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56574. SSF56574. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Liver.

    Entry informationi

    Entry nameiSPA11_MOUSE
    AccessioniPrimary (citable) accession number: Q8CIE0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 27, 2005
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3