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Q8CIE0 (SPA11_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serpin A11
Gene names
Name:Serpina11
Synonyms:Gm895
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length424 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the serpin family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionProtease inhibitor
Serine protease inhibitor
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processregulation of proteolysis

Inferred from Biological aspect of Ancestor. Source: RefGenome

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionserine-type endopeptidase inhibitor activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 424403Serpin A11
PRO_0000041974

Amino acid modifications

Glycosylation1081N-linked (GlcNAc...) Potential
Glycosylation1711N-linked (GlcNAc...) Potential
Glycosylation3521N-linked (GlcNAc...) Potential
Glycosylation3871N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q8CIE0 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: D176AAF8D5A06D34

FASTA42447,188
        10         20         30         40         50         60 
MGPVWLWLWL LVAEVLLPVH CQPFSAHGDK SLGASQPASH QSLEPAPAYH KVTPTITNFA 

        70         80         90        100        110        120 
LRLYKQLAEE VAGNILFSPV SLSSSLALLS LGAHADTQTQ ILESLGFNLT ETPAADVHRG 

       130        140        150        160        170        180 
FQSLLHTLDL PSPKLELKLG HSLFLDRQLK PQQRFLDSAK ELYGALAFSA NFTEAAATGQ 

       190        200        210        220        230        240 
QINDLVRKQT YGQVVGCLPE FSHDTLMVLL NYIFFKAKWK HPFDRYQTRK QESFSLDQRT 

       250        260        270        280        290        300 
PLRIPMMRQK EMHRFLYDQE ASCTVLQIEY SGTALLLLVL PDPGKMQQVE AALQPETLRR 

       310        320        330        340        350        360 
WGQRFLPSLL DLHLPRFSIS ATYNLEEILP LIGLGNLFDM EADLSGIMGQ LNKTVSRVSH 

       370        380        390        400        410        420 
KAIVDMNEKG TEAAAASGLL SQPPALNMTS APQAHYNRPF LLLLWEVTTQ SLLFLGKVVN 


PAAG

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Liver.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC024087 mRNA. Translation: AAH24087.1.
BC096585 mRNA. Translation: AAH96585.1.
IPIIPI00229829.
RefSeqNP_955018.2. NM_199314.2.
UniGeneMm.201338.

3D structure databases

ProteinModelPortalQ8CIE0.
SMRQ8CIE0. Positions 57-421.
ModBaseSearch...

Protein family/group databases

MEROPSI04.955.

PTM databases

PhosphoSiteQ8CIE0.

Proteomic databases

PaxDbQ8CIE0.
PRIDEQ8CIE0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID380780.
KEGGmmu:380780.

Organism-specific databases

CTD256394.
MGIMGI:2685741. Serpina11.

Phylogenomic databases

eggNOGCOG4826.
HOGENOMHOG000238521.
HOVERGENHBG005957.
InParanoidQ8CIE0.
OrthoDBEOG4FFD1T.

Gene expression databases

GenevestigatorQ8CIE0.
GermOnlineENSMUSG00000063232. Mus musculus.

Family and domain databases

InterProIPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERPTHR11461. PTHR11461. 1 hit.
PfamPF00079. Serpin. 1 hit.
[Graphical view]
SMARTSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMSSF56574. Prot_inh_serpin. 1 hit.
PROSITEPS00284. SERPIN. False negative.
[Graphical view]
ProtoNetSearch...

Other

NextBio401226.
SOURCESearch...

Entry information

Entry nameSPA11_MOUSE
AccessionPrimary (citable) accession number: Q8CIE0
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: March 1, 2003
Last modified: May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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