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Protein

Required for meiotic nuclear division protein 1 homolog

Gene

Rmnd1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Required for meiotic nuclear division protein 1 homolog
Gene namesi
Name:Rmnd1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1913334. Rmnd1.

Subcellular locationi

  • Mitochondrion By similarity

  • Note: May be localized in mitochondrial RNA granules.By similarity

GO - Cellular componenti

  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 55MitochondrionSequence analysis
Chaini6 – 450445Required for meiotic nuclear division protein 1 homologPRO_0000229734Add
BLAST

Proteomic databases

MaxQBiQ8CI78.
PaxDbiQ8CI78.
PeptideAtlasiQ8CI78.
PRIDEiQ8CI78.

PTM databases

PhosphoSiteiQ8CI78.

Expressioni

Gene expression databases

BgeeiENSMUSG00000019763.
ExpressionAtlasiQ8CI78. baseline and differential.
GenevisibleiQ8CI78. MM.

Interactioni

Subunit structurei

Homooligomer.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043355.

Structurei

3D structure databases

ProteinModelPortaliQ8CI78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RMD1/sif2 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG2861. Eukaryota.
COG1723. LUCA.
GeneTreeiENSGT00390000013337.
HOVERGENiHBG093175.
InParanoidiQ8CI78.
OMAiMKHVMKV.
OrthoDBiEOG091G09ZY.
PhylomeDBiQ8CI78.
TreeFamiTF105813.

Family and domain databases

InterProiIPR003734. DUF155.
[Graphical view]
PfamiPF02582. DUF155. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8CI78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSRLLHTLA SLHSISAKAH QCQRLTWLTL RPLRKSESTT CHNGLTIQQH
60 70 80 90 100
LHSFFPSITA DSLNKPEILE MSRITSDTSR LFPLNAVHWL DGKEHWPSMH
110 120 130 140 150
PFGTHRSMTH KPNLLCSKWF IKAVKRHHSS VSNEALVPKQ DLPQIKRPLK
160 170 180 190 200
ASRTRQPSRT NLPDLSVNED LMQCTAFATA DEYHLGSLSQ ELVSCGYVEV
210 220 230 240 250
TSLPRDAANI LVMGVESSAK EGDPGTIFLF REGAAVFWNV KEKTMKHVMQ
260 270 280 290 300
VLERHETQPY EVALVHWENE ELNYIKTEGQ SKLHRGEIKL NSELDLDDAI
310 320 330 340 350
LEKFAFSNAL CLSVKLAIWE ATLDKFIESI QSIPEALKAG KKVKLSHKEV
360 370 380 390 400
MQKMGELFAL RHRINLSSDF LITPDFYWDR ANLEELYDKT CQFLSITRRV
410 420 430 440 450
KVMNEKLQHC MELTDLMRNH LNEKRALRLE WMIVILITIE VMFELGRVFF
Length:450
Mass (Da):51,843
Last modified:March 1, 2003 - v1
Checksum:iE085AE029FFA3822
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti41 – 411C → S in BAC35851 (PubMed:16141072).Curated
Sequence conflicti68 – 681I → R in AAH27299 (PubMed:15489334).Curated
Sequence conflicti74 – 763ITS → VTW in AAH27299 (PubMed:15489334).Curated
Sequence conflicti130 – 1301S → T in AAH27299 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007323 mRNA. Translation: BAB24958.1.
AK009625 mRNA. Translation: BAB26398.1.
AK075603 mRNA. Translation: BAC35851.1.
AK163523 mRNA. Translation: BAE37381.1.
BC019572 mRNA. Translation: AAH19572.1.
BC027299 mRNA. Translation: AAH27299.1.
BC036150 mRNA. Translation: AAH36150.1.
CCDSiCCDS56675.1.
RefSeqiNP_079619.4. NM_025343.5.
XP_006512539.1. XM_006512476.2.
XP_006512540.1. XM_006512477.2.
XP_006512541.1. XM_006512478.2.
XP_011241400.1. XM_011243098.1.
UniGeneiMm.153111.
Mm.313137.

Genome annotation databases

EnsembliENSMUST00000042251; ENSMUSP00000043355; ENSMUSG00000019763.
GeneIDi66084.
KEGGimmu:66084.
UCSCiuc007ehd.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007323 mRNA. Translation: BAB24958.1.
AK009625 mRNA. Translation: BAB26398.1.
AK075603 mRNA. Translation: BAC35851.1.
AK163523 mRNA. Translation: BAE37381.1.
BC019572 mRNA. Translation: AAH19572.1.
BC027299 mRNA. Translation: AAH27299.1.
BC036150 mRNA. Translation: AAH36150.1.
CCDSiCCDS56675.1.
RefSeqiNP_079619.4. NM_025343.5.
XP_006512539.1. XM_006512476.2.
XP_006512540.1. XM_006512477.2.
XP_006512541.1. XM_006512478.2.
XP_011241400.1. XM_011243098.1.
UniGeneiMm.153111.
Mm.313137.

3D structure databases

ProteinModelPortaliQ8CI78.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043355.

PTM databases

PhosphoSiteiQ8CI78.

Proteomic databases

MaxQBiQ8CI78.
PaxDbiQ8CI78.
PeptideAtlasiQ8CI78.
PRIDEiQ8CI78.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042251; ENSMUSP00000043355; ENSMUSG00000019763.
GeneIDi66084.
KEGGimmu:66084.
UCSCiuc007ehd.2. mouse.

Organism-specific databases

CTDi55005.
MGIiMGI:1913334. Rmnd1.

Phylogenomic databases

eggNOGiKOG2861. Eukaryota.
COG1723. LUCA.
GeneTreeiENSGT00390000013337.
HOVERGENiHBG093175.
InParanoidiQ8CI78.
OMAiMKHVMKV.
OrthoDBiEOG091G09ZY.
PhylomeDBiQ8CI78.
TreeFamiTF105813.

Miscellaneous databases

PROiQ8CI78.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000019763.
ExpressionAtlasiQ8CI78. baseline and differential.
GenevisibleiQ8CI78. MM.

Family and domain databases

InterProiIPR003734. DUF155.
[Graphical view]
PfamiPF02582. DUF155. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRMND1_MOUSE
AccessioniPrimary (citable) accession number: Q8CI78
Secondary accession number(s): Q3TQK1
, Q8BW19, Q8R2S0, Q8VCK4, Q9CV49, Q9CVN0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.