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Q8CHS4

- PLCX1_MOUSE

UniProt

Q8CHS4 - PLCX1_MOUSE

Protein

PI-PLC X domain-containing protein 1

Gene

Plcxd1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. phosphoric diester hydrolase activity Source: InterPro

    GO - Biological processi

    1. lipid metabolic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    PI-PLC X domain-containing protein 1
    Gene namesi
    Name:Plcxd1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Unplaced

    Organism-specific databases

    MGIiMGI:2685422. Plcxd1.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 345345PI-PLC X domain-containing protein 1PRO_0000304805Add
    BLAST

    PTM databases

    PhosphoSiteiQ8CHS4.

    Expressioni

    Gene expression databases

    BgeeiQ8CHS4.
    GenevestigatoriQ8CHS4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CHS4.
    SMRiQ8CHS4. Positions 45-213.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini52 – 228177PI-PLC X-boxPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 PI-PLC X-box domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG311948.
    HOGENOMiHOG000007180.
    HOVERGENiHBG099748.
    InParanoidiQ8CHS4.
    PhylomeDBiQ8CHS4.

    Family and domain databases

    Gene3Di3.20.20.190. 1 hit.
    InterProiIPR017946. PLC-like_Pdiesterase_TIM-brl.
    IPR000909. PLipase_C_PInositol-sp_X_dom.
    [Graphical view]
    PfamiPF00388. PI-PLC-X. 1 hit.
    [Graphical view]
    SUPFAMiSSF51695. SSF51695. 1 hit.
    PROSITEiPS50007. PIPLC_X_DOMAIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8CHS4-1 [UniParc]FASTAAdd to Basket

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    MQGLEPSRVG RVGEVCRSVH KNVLTVPEHT VGTEAAAPMG DQADWMSQLC    50
    PQLWDVPLHH LSIPGSHDTM TYCLNRKSRI SRASSWLLHL LGRVVPFITG 100
    PVVMKWSVTQ TLDVTQQLDA GVRYLDLRIA HAPEGSTRNL CFVHMMYTKA 150
    LVEDTLTEIA EWLQSHPREV VILACRNFEG MTCELHDYLA GCIVNIFGDM 200
    LCPSGEVPTL RQLWAREQQV IVSYEDEATV SRYDQLWPAI PYWWGNAVKT 250
    DVLLRFLETM KGQGRPDGLF VAGINITENL CYILLHPVDS LEEMTRRSLP 300
    LMTEWVCAQQ PGQSPQCTNI IAGDFVDADG FVSKVISLNC KLLSP 345
    Length:345
    Mass (Da):38,718
    Last modified:March 1, 2003 - v1
    Checksum:i7D83AD5926C40A56
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti339 – 3391N → S in BAC30356. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK039459 mRNA. Translation: BAC30356.1.
    BC039627 mRNA. Translation: AAH39627.1.
    UniGeneiMm.297057.

    Genome annotation databases

    UCSCiuc012eax.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK039459 mRNA. Translation: BAC30356.1 .
    BC039627 mRNA. Translation: AAH39627.1 .
    UniGenei Mm.297057.

    3D structure databases

    ProteinModelPortali Q8CHS4.
    SMRi Q8CHS4. Positions 45-213.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q8CHS4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc012eax.1. mouse.

    Organism-specific databases

    MGIi MGI:2685422. Plcxd1.

    Phylogenomic databases

    eggNOGi NOG311948.
    HOGENOMi HOG000007180.
    HOVERGENi HBG099748.
    InParanoidi Q8CHS4.
    PhylomeDBi Q8CHS4.

    Miscellaneous databases

    ChiTaRSi PLCXD1. mouse.
    PROi Q8CHS4.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8CHS4.
    Genevestigatori Q8CHS4.

    Family and domain databases

    Gene3Di 3.20.20.190. 1 hit.
    InterProi IPR017946. PLC-like_Pdiesterase_TIM-brl.
    IPR000909. PLipase_C_PInositol-sp_X_dom.
    [Graphical view ]
    Pfami PF00388. PI-PLC-X. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51695. SSF51695. 1 hit.
    PROSITEi PS50007. PIPLC_X_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Czech II.
      Tissue: Mammary tumor.
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 46-345.
      Strain: C57BL/6J.
      Tissue: Spinal cord.

    Entry informationi

    Entry nameiPLCX1_MOUSE
    AccessioniPrimary (citable) accession number: Q8CHS4
    Secondary accession number(s): Q8BYI5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3