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Protein

PI-PLC X domain-containing protein 1

Gene

Plcxd1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
PI-PLC X domain-containing protein 1
Gene namesi
Name:Plcxd1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:2685422. Plcxd1.

Subcellular locationi

  • Cytoplasm By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003048051 – 345PI-PLC X domain-containing protein 1Add BLAST345

Proteomic databases

PaxDbiQ8CHS4.
PRIDEiQ8CHS4.

PTM databases

PhosphoSitePlusiQ8CHS4.

Expressioni

Tissue specificityi

Expressed at highest levels in brain and kidney. Also detected in stomach, thymus and skeletal muscle.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000083892.

Structurei

3D structure databases

ProteinModelPortaliQ8CHS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 228PI-PLC X-boxPROSITE-ProRule annotationAdd BLAST177

Phylogenomic databases

eggNOGiKOG4306. Eukaryota.
ENOG410Z30Q. LUCA.
HOGENOMiHOG000007180.
HOVERGENiHBG099748.
InParanoidiQ8CHS4.
PhylomeDBiQ8CHS4.

Family and domain databases

Gene3Di3.20.20.190. 1 hit.
InterProiView protein in InterPro
IPR017946. PLC-like_Pdiesterase_TIM-brl.
IPR000909. PLipase_C_PInositol-sp_X_dom.
PfamiView protein in Pfam
PF00388. PI-PLC-X. 1 hit.
SMARTiView protein in SMART
SM00148. PLCXc. 1 hit.
SUPFAMiSSF51695. SSF51695. 1 hit.
PROSITEiView protein in PROSITE
PS50007. PIPLC_X_DOMAIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8CHS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQGLEPSRVG RVGEVCRSVH KNVLTVPEHT VGTEAAAPMG DQADWMSQLC
60 70 80 90 100
PQLWDVPLHH LSIPGSHDTM TYCLNRKSRI SRASSWLLHL LGRVVPFITG
110 120 130 140 150
PVVMKWSVTQ TLDVTQQLDA GVRYLDLRIA HAPEGSTRNL CFVHMMYTKA
160 170 180 190 200
LVEDTLTEIA EWLQSHPREV VILACRNFEG MTCELHDYLA GCIVNIFGDM
210 220 230 240 250
LCPSGEVPTL RQLWAREQQV IVSYEDEATV SRYDQLWPAI PYWWGNAVKT
260 270 280 290 300
DVLLRFLETM KGQGRPDGLF VAGINITENL CYILLHPVDS LEEMTRRSLP
310 320 330 340
LMTEWVCAQQ PGQSPQCTNI IAGDFVDADG FVSKVISLNC KLLSP
Length:345
Mass (Da):38,718
Last modified:March 1, 2003 - v1
Checksum:i7D83AD5926C40A56
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti339N → S in BAC30356 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK039459 mRNA. Translation: BAC30356.1.
BC039627 mRNA. Translation: AAH39627.1.
UniGeneiMm.297057.

Genome annotation databases

UCSCiuc012eax.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiPLCX1_MOUSE
AccessioniPrimary (citable) accession number: Q8CHS4
Secondary accession number(s): Q8BYI5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2003
Last modified: August 30, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot