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Q8CHS4 (PLCX1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
PI-PLC X domain-containing protein 1
Gene names
Name:Plcxd1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PI-PLC X-box domain.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processlipid metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionphosphoric diester hydrolase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 345345PI-PLC X domain-containing protein 1
PRO_0000304805

Regions

Domain52 – 228177PI-PLC X-box

Experimental info

Sequence conflict3391N → S in BAC30356. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q8CHS4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 7D83AD5926C40A56

FASTA34538,718
        10         20         30         40         50         60 
MQGLEPSRVG RVGEVCRSVH KNVLTVPEHT VGTEAAAPMG DQADWMSQLC PQLWDVPLHH 

        70         80         90        100        110        120 
LSIPGSHDTM TYCLNRKSRI SRASSWLLHL LGRVVPFITG PVVMKWSVTQ TLDVTQQLDA 

       130        140        150        160        170        180 
GVRYLDLRIA HAPEGSTRNL CFVHMMYTKA LVEDTLTEIA EWLQSHPREV VILACRNFEG 

       190        200        210        220        230        240 
MTCELHDYLA GCIVNIFGDM LCPSGEVPTL RQLWAREQQV IVSYEDEATV SRYDQLWPAI 

       250        260        270        280        290        300 
PYWWGNAVKT DVLLRFLETM KGQGRPDGLF VAGINITENL CYILLHPVDS LEEMTRRSLP 

       310        320        330        340 
LMTEWVCAQQ PGQSPQCTNI IAGDFVDADG FVSKVISLNC KLLSP 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Czech II.
Tissue: Mammary tumor.
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 46-345.
Strain: C57BL/6J.
Tissue: Spinal cord.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK039459 mRNA. Translation: BAC30356.1.
BC039627 mRNA. Translation: AAH39627.1.
UniGeneMm.297057.

3D structure databases

ProteinModelPortalQ8CHS4.
SMRQ8CHS4. Positions 45-213.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ8CHS4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc012eax.1. mouse.

Organism-specific databases

MGIMGI:2685422. Plcxd1.

Phylogenomic databases

eggNOGNOG311948.
HOGENOMHOG000007180.
HOVERGENHBG099748.
InParanoidQ8CHS4.
PhylomeDBQ8CHS4.

Gene expression databases

BgeeQ8CHS4.
GenevestigatorQ8CHS4.

Family and domain databases

Gene3D3.20.20.190. 1 hit.
InterProIPR017946. PLC-like_Pdiesterase_TIM-brl.
IPR000909. PLipase_C_PInositol-sp_X_dom.
[Graphical view]
PfamPF00388. PI-PLC-X. 1 hit.
[Graphical view]
SUPFAMSSF51695. SSF51695. 1 hit.
PROSITEPS50007. PIPLC_X_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPLCXD1. mouse.
PROQ8CHS4.
SOURCESearch...

Entry information

Entry namePLCX1_MOUSE
AccessionPrimary (citable) accession number: Q8CHS4
Secondary accession number(s): Q8BYI5
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot