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Protein
Submitted name:

P2X purinoceptor 7

Gene

P2rx7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
P2X purinoceptor 7Imported
Gene namesi
Name:P2rx7Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1339957. P2rx7.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8CHP4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000029468.
GenevisibleiQ8CHP4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000098303.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IK4U. Eukaryota.
ENOG4110DDY. LUCA.
HOVERGENiHBG053086.
KOiK05220.
OMAiLCPEYPT.
OrthoDBiEOG091G0A2U.

Family and domain databases

Gene3Di2.60.490.10. 1 hit.
InterProiIPR003050. P2X7_purnocptor.
IPR027309. P2X_extracellular_dom.
IPR001429. P2X_purnocptor.
[Graphical view]
PANTHERiPTHR10125. PTHR10125. 3 hits.
PTHR10125:SF13. PTHR10125:SF13. 3 hits.
PfamiPF00864. P2X_receptor. 1 hit.
[Graphical view]
PRINTSiPR01314. P2X7RECEPTOR.
PR01307. P2XRECEPTOR.
TIGRFAMsiTIGR00863. P2X. 1 hit.
PROSITEiPS01212. P2X_RECEPTOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8CHP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPACCSWNDV LQYETNKVTR IQSTNYGTVK WVLHMIVFSY ISFALVSDKL
60 70 80 90 100
YQRKEPVISS VHTKVKGIAE VTENVTEGGV TKLGHSIFDT ADYTFPLQGN
110 120 130 140 150
SFFVMTNYVK SEGQVQTLCP EYPRRGAQCS SDRRCKKGWM DPQSKGIQTG
160 170 180 190 200
RCVPYDKTRK TCEVSAWCPT EEEKEAPRPA LLRSAENFTV LIKNNIHFPG
210 220 230 240 250
HNYTTRNILP TMNGSCTFHK TWDPQCSIFR LGDIFQEAGE NFTEVAVQGG
260 270 280 290 300
IMGIEIYWDC NLDSWSHHCR PRYSFRRLDD KNTDESFVPG YNFRYAKYYK
310 320 330 340 350
ENNVEKRTLI KAFGIRFDIL VFGTGGKFDI IQLVVYIGST LSYFGLATVC
360 370 380 390 400
IDLLINTYSS AFCRSGVYPY CKCCEPCTVN EYYYRKKCES IMEPKPTLKY
410 420 430 440 450
VSFVDEPHIR MVDQQLLGKS LQVVKGQEVP RPQMDFSDLS RLSLSLHDSP
460 470 480 490 500
LTPGQSEEIQ LLHEEVAPKS GDSPSWCQCG NCLPSRLPEQ RRALEELCCR
510 520 530 540 550
RKPGRCITTS KLFHKLVLSR DTLQLLLLYQ DPLLVLGEEA TNSRLRHRAY
560 570 580 590
RCYATWRFGS QDMADFAILP SCCRWRIRKE FPKTEGQYSG FKYPY
Length:595
Mass (Da):68,388
Last modified:March 1, 2003 - v1
Checksum:iBE007FE195AF50A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ489296 mRNA. Translation: CAD33538.1.
RefSeqiNP_001033928.1. NM_001038839.2.
NP_035157.2. NM_011027.3.
UniGeneiMm.42026.

Genome annotation databases

GeneIDi18439.
KEGGimmu:18439.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ489296 mRNA. Translation: CAD33538.1.
RefSeqiNP_001033928.1. NM_001038839.2.
NP_035157.2. NM_011027.3.
UniGeneiMm.42026.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000098303.

Proteomic databases

PRIDEiQ8CHP4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi18439.
KEGGimmu:18439.

Organism-specific databases

CTDi5027.
MGIiMGI:1339957. P2rx7.

Phylogenomic databases

eggNOGiENOG410IK4U. Eukaryota.
ENOG4110DDY. LUCA.
HOVERGENiHBG053086.
KOiK05220.
OMAiLCPEYPT.
OrthoDBiEOG091G0A2U.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029468.
GenevisibleiQ8CHP4. MM.

Family and domain databases

Gene3Di2.60.490.10. 1 hit.
InterProiIPR003050. P2X7_purnocptor.
IPR027309. P2X_extracellular_dom.
IPR001429. P2X_purnocptor.
[Graphical view]
PANTHERiPTHR10125. PTHR10125. 3 hits.
PTHR10125:SF13. PTHR10125:SF13. 3 hits.
PfamiPF00864. P2X_receptor. 1 hit.
[Graphical view]
PRINTSiPR01314. P2X7RECEPTOR.
PR01307. P2XRECEPTOR.
TIGRFAMsiTIGR00863. P2X. 1 hit.
PROSITEiPS01212. P2X_RECEPTOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8CHP4_MOUSE
AccessioniPrimary (citable) accession number: Q8CHP4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.