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Q8CHM5

- Q8CHM5_MOUSE

UniProt

Q8CHM5 - Q8CHM5_MOUSE

Protein
Submitted name:

Ribosomal protein S6 kinase

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.SAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. magnesium ion binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro

    Keywords - Molecular functioni

    Kinase, Ribonucleoprotein, Ribosomal proteinImported, Serine/threonine-protein kinaseSAAS annotation, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ribosomal protein S6 kinaseImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    Expressioni

    Gene expression databases

    GenevestigatoriQ8CHM5.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000024619.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8CHM5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains AGC-kinase C-terminal domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000233033.
    HOVERGENiHBG108317.
    InParanoidiQ8CHM5.

    Family and domain databases

    InterProiIPR000961. AGC-kinase_C.
    IPR011009. Kinase-like_dom.
    IPR017892. Pkinase_C.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR016239. Ribosomal_S6_kinase_II.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 2 hits.
    PF00433. Pkinase_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000606. Ribsml_S6_kin_2. 1 hit.
    SMARTiSM00133. S_TK_X. 1 hit.
    SM00220. S_TKc. 2 hits.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 2 hits.
    PROSITEiPS51285. AGC_KINASE_CTER. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 2 hits.
    PS50011. PROTEIN_KINASE_DOM. 2 hits.
    PS00108. PROTEIN_KINASE_ST. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8CHM5-1 [UniParc]FASTAAdd to Basket

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    EEGIVKEIDI SNHVKEGFEK ADPSQFELLK VLGQGSYGKV FLVRKVTGSD    50
    AGQLYAMKVL KKATLKVRDR VRSKMERDIL AEVNHPFIVK LHYAFQTEGK 100
    LYLILDFLRG GDLFTRLSKE VMFTEEDVKF YLAELALALD HLHGLGIIYR 150
    DLKPENILLD EEGHIKITDF GLSKEATDHD KRAYSFCGTI EYMAPEVVNR 200
    RGHTQSADWW SFGVLMFEML TGSLPFQGKD RKETMALILK AKLGMPQFLS 250
    AEAQSLLRAL FKRNPCNRLG AGVDGVEEIK RHPFFVTIDW NKLYRKEIKP 300
    PFKPAVGRPE DTFHFDPEFT ARTPTDSPGV PPSANAHHLF RGFSFVASSL 350
    VQEPSQQDVP KAPIHPIVQQ LHGNNIHFTD GYEIKEDIGV GSYSVCKRCV 400
    HKATDAEYAV KIIDKSKRDP SEEIEILLRY GQHPNIITLK DVYDDGKYVY 450
    LVMELMRGGE LLDRILRQRC FSEREASDVL YTIARTMDYL HSQGVGLPAL 500
    PVVVHRDLKP SNILYMDESG NPESIRICDF GFAKQLRAEN GLLMTPCYTA 550
    NFVAPEVLKR QGYDAACDVW SLGILLYTML AGFTPFANGP DDTPEEILAR 600
    IGSGKYALSG GNWDSISDAA KDVVSKMLHV DPQQRLTAVQ VLKHPWIVNR 650
    EYLSQNQLSR QDVHLVKGAM AATYFALNRT PQAPRLEPVL SSSLAQRRGM 700
    KRLTSTRL 708
    Length:708
    Mass (Da):79,908
    Last modified:March 1, 2003 - v1
    Checksum:i156CDD42B331307E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF551762 Genomic DNA. Translation: AAN71007.1.
    UniGeneiMm.268383.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF551762 Genomic DNA. Translation: AAN71007.1 .
    UniGenei Mm.268383.

    3D structure databases

    ProteinModelPortali Q8CHM5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000024619.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000233033.
    HOVERGENi HBG108317.
    InParanoidi Q8CHM5.

    Gene expression databases

    Genevestigatori Q8CHM5.

    Family and domain databases

    InterProi IPR000961. AGC-kinase_C.
    IPR011009. Kinase-like_dom.
    IPR017892. Pkinase_C.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR016239. Ribosomal_S6_kinase_II.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 2 hits.
    PF00433. Pkinase_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000606. Ribsml_S6_kin_2. 1 hit.
    SMARTi SM00133. S_TK_X. 1 hit.
    SM00220. S_TKc. 2 hits.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 2 hits.
    PROSITEi PS51285. AGC_KINASE_CTER. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 2 hits.
    PS50011. PROTEIN_KINASE_DOM. 2 hits.
    PS00108. PROTEIN_KINASE_ST. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genomic Sequence Analysis in the Mouse T-complex Region."
      Brathwaite M., Waeltz P., Dudekula D., Qian Y., Schlessinger D., Nagaraja R.
      Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 129/SvJImported.

    Entry informationi

    Entry nameiQ8CHM5_MOUSE
    AccessioniPrimary (citable) accession number: Q8CHM5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)