Q8CHM5 (Q8CHM5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ribosomal protein S6 kinase EMBL AAN71007.1

Gene names

Name:

Rps6ka2 MGI 1342290

Organism

Mus musculus (Mouse) EMBL AAN71007.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	708 AA.
Sequence status	Fragment.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS017892
Sequence similarities	Contains 1 AGC-kinase C-terminal domain. SAAS SAAS017892

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS017892 RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase Ribonucleoprotein Ribosomal protein EMBL AAN71007.1 Serine/threonine-protein kinase SAAS SAAS017892 Transferase
Gene Ontology (GO)
Biological_process	intracellular protein kinase cascade Inferred from electronic annotation. Source: InterPro
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW magnesium ion binding Inferred from electronic annotation. Source: InterPro protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAN71007.1

Sequences

	Sequence		Length	Mass (Da)
	Q8CHM5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 156CDD42B331307E	FASTA	708	79,908
	10 20 30 40 50 60 EEGIVKEIDI SNHVKEGFEK ADPSQFELLK VLGQGSYGKV FLVRKVTGSD AGQLYAMKVL 70 80 90 100 110 120 KKATLKVRDR VRSKMERDIL AEVNHPFIVK LHYAFQTEGK LYLILDFLRG GDLFTRLSKE 130 140 150 160 170 180 VMFTEEDVKF YLAELALALD HLHGLGIIYR DLKPENILLD EEGHIKITDF GLSKEATDHD 190 200 210 220 230 240 KRAYSFCGTI EYMAPEVVNR RGHTQSADWW SFGVLMFEML TGSLPFQGKD RKETMALILK 250 260 270 280 290 300 AKLGMPQFLS AEAQSLLRAL FKRNPCNRLG AGVDGVEEIK RHPFFVTIDW NKLYRKEIKP 310 320 330 340 350 360 PFKPAVGRPE DTFHFDPEFT ARTPTDSPGV PPSANAHHLF RGFSFVASSL VQEPSQQDVP 370 380 390 400 410 420 KAPIHPIVQQ LHGNNIHFTD GYEIKEDIGV GSYSVCKRCV HKATDAEYAV KIIDKSKRDP 430 440 450 460 470 480 SEEIEILLRY GQHPNIITLK DVYDDGKYVY LVMELMRGGE LLDRILRQRC FSEREASDVL 490 500 510 520 530 540 YTIARTMDYL HSQGVGLPAL PVVVHRDLKP SNILYMDESG NPESIRICDF GFAKQLRAEN 550 560 570 580 590 600 GLLMTPCYTA NFVAPEVLKR QGYDAACDVW SLGILLYTML AGFTPFANGP DDTPEEILAR 610 620 630 640 650 660 IGSGKYALSG GNWDSISDAA KDVVSKMLHV DPQQRLTAVQ VLKHPWIVNR EYLSQNQLSR 670 680 690 700 QDVHLVKGAM AATYFALNRT PQAPRLEPVL SSSLAQRRGM KRLTSTRL

References

[1]	"Genomic Sequence Analysis in the Mouse T-complex Region." Brathwaite M., Waeltz P., Dudekula D., Qian Y., Schlessinger D., Nagaraja R. Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 129/SvJ EMBL AAN71007.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF551762 Genomic DNA. Translation: AAN71007.1.
IPI	IPI00758052.
UniGene	Mm.268383.
3D structure databases
HSSP	HSSP built from PDB template 1GZK based on UniProtKB P31751.
ProteinModelPortal	Q8CHM5.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000024619.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000233033.
HOVERGEN	HBG108317.
InParanoid	Q8CHM5.
Gene expression databases
Genevestigator	Q8CHM5.
Family and domain databases
InterPro	IPR000961. AGC-kinase_C. IPR011009. Kinase-like_dom. IPR017892. Pkinase_C. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR016239. Ribosomal_S6_kinase_II. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 2 hits. PF00433. Pkinase_C. 1 hit. [Graphical view]
PIRSF	PIRSF000606. Ribsml_S6_kin_2. 1 hit.
SMART	SM00133. S_TK_X. 1 hit. SM00220. S_TKc. 2 hits. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 2 hits.
PROSITE	PS51285. AGC_KINASE_CTER. 1 hit. PS00107. PROTEIN_KINASE_ATP. 2 hits. PS50011. PROTEIN_KINASE_DOM. 2 hits. PS00108. PROTEIN_KINASE_ST. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8CHM5_MOUSE

Accession

Primary (citable) accession number: Q8CHM5

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	April 3, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)